Zobrazeno 1 - 10
of 28
pro vyhledávání: '"B. E. Dunning"'
Publikováno v:
Diabetes, Obesity and Metabolism. 13:775-783
Inhibition of dipeptidyl peptidase-4 (DPP-4) by vildagliptin prevents degradation of glucagon-like peptide-1 (GLP-1) and reduces glycaemia in patients with type 2 diabetes mellitus, with low risk for hypoglycaemia and no weight gain. Vildagliptin bin
Autor:
L S, Phillips, B E, Dunning
Publikováno v:
International Journal of Clinical Practice. 57:535-541
Nateglinide is a new oral antidiabetic agent that stimulates insulin release promptly after its pre-meal administration in a strongly glucose-dependent fashion. Because its insulinotropic effects are short in duration, nateglinide specifically target
Autor:
B. Balkan, B. E. Dunning
Publikováno v:
Diabetes. 43:1173-1179
Autor:
B. E. Dunning, Bo Ahrén
Publikováno v:
Acta Physiologica Scandinavica. 149:215-219
Galanin inhibits insulin secretion and has been proposed to function as a sympathetic neurotransmitter in the endocrine pancreas in some species, for example in the dog. In this study, pancreatic and adrenal gland galanin content were measured follow
Publikováno v:
Acta Physiologica Scandinavica. 143:145-152
This study examines the potential role of the neuropeptide, galanin, in stress-induced inhibition of insulin secretion in swimming mice. Firstly, the pancreatic and adrenal content of galanin-like immunoreactivity was determined in mice after swimmin
Publikováno v:
Cell and Tissue Research. 264:263-267
In several animal species, galanin occurs in pancreatic nerves and inhibits insulin secretion. However, the presence and action of galanin in the human pancreas have not been established. Therefore, we examined the presence and nature of human pancre
Publikováno v:
Acta Physiologica Scandinavica. 139:591-596
It is known that pig galanin inhibits insulin secretion in dogs, rats and mice. The present study examined whether species-specific, homologous, galanin inhibits insulin secretion. Thus, the effects of rat galanin were examined in the rat, and the ef
Publikováno v:
Cell and Tissue Research. 261:49-58
To visualize the localization and potential co-localization of noradrenaline and the putative pancreatic sympathetic neurotransmitters, galanin and neuropeptide Y (NPY), immunofluorescent staining for galanin, NPY and tyrosine hydroxylase (TH) was pe
Publikováno v:
Diabetes care. 24(6)
This study compared the effects of nateglinide, glyburide, and placebo on postmeal glucose excursions and insulin secretion in previously diet-treated patients with type 2 diabetes.This randomized, double-blind, placebo-controlled multicenter study w
Publikováno v:
Diabetes, obesitymetabolism. 3(2)
Abnormal beta-cell function, characterized as the inability of the beta-cell to mount a rapid secretory response to glucose, is a well-established pathology of type 2 diabetes mellitus. These studies were designed to demonstrate the importance of ear