Zobrazeno 1 - 10
of 95
pro vyhledávání: '"B. Desfosses"'
Autor:
Philippe Valadon, B. Desfosses, Daniel Mansuy, Catherine Pons, Eric Bonierbale, Patrick M. Dansette
Publikováno v:
Chemical research in toxicology. 12(3)
Tienilic acid (TA) is responsible for an immune-mediated drug-induced hepatitis in humans, while its isomer (TAI) triggers a direct hepatitis in rats. In this study, we describe an immunological approach developed for studying the specificity of the
Publikováno v:
FEBS letters. 443(2)
The temperature and pH dependence as well as the selectivity of the peroxidase activity of a complex associating a monoclonal antibody 13G10 with its iron(III)-alpha,alpha,alpha,beta-mesotetrakis(ortho-carboxyphenyl) porphyrin (Fe(ToCPP)) hapten have
Publikováno v:
Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie. 317(5)
Antibodies were raised against 3-fluoro-4-aza-estradiol-17-hemisuccinate to elicit abzymes capable of isomerizing delta 5-3-ketosteroids. The hapten was designed to present a planar A ring showing some analogy with the intermediate dienol and a polar
Publikováno v:
Analytical Biochemistry. 159:179-186
A series of fluorescent disulfononaphthalimide (lucifer yellow) derivatives of testosterone and estriol have been synthesized: testosterone-3- and estriol-6-ureidooxime-lucifer yellow, testosterone-3-and estriol-6-(amidoureido)methoxyoxime lucifer ye
Autor:
R. Condom, B. Desfosses
Publikováno v:
Journal of Steroid Biochemistry. 8:1165-1169
The 15α-carboxymethyl derivative of testosterone has been prepared from 15α-carboxymethyl-DHA, the latter has been described previously [1]. The sequence involved formation of the tetrahydropyranoxy derivative at C-3, reduction of carbonyl at C-17
Publikováno v:
Steroids. 22:747-761
The study of several antiestriol antisera in the presence of a series of analogues of estriol has led to a critical discussion of the classical cross-reaction test. A more accurate test (CR 1 ng) which permits a more precise determination of specific
Publikováno v:
The Journal of Immunology. 143:4078-4083
Immunization with a murine anti-aldosterone mAb (AAC) resulted in the isolation of a syngeneic monoclonal anti-idiotypic antibody, LH9G4. LH9G4 bound to Fab fragments of AAC and was affinity-purified on an AAC column. LH9G4 inhibited the binding of a
Publikováno v:
Journal of Steroid Biochemistry. 8:1263-1268
Antisera against androsterone and 5α-androstane-3,17β-diol were raised in rabbits with conjugates obtained by coupling 15α-carboxymethylandrosterone, 1α-carboxymethyl-5α-androstane-3α,17β-diol, 15α-carboxymethyl-5α-androstane-3α,17β-diol,
Publikováno v:
Steroids. 29:701-713
The formation of a horseradish peroxidase-testosterone conjugate for the enzyme-linked immunoassay of testosterone was investigated, using tritiated testosterone to follow the reaction. The formation of testosterone-3-(carboxymethyl) oxime-peroxidase
Publikováno v:
Clinica Chimica Acta. 72:275-284
This paper describes a study of the physico-chemical and radioimmunological properties of three antialdosterone antisera which permitted practical conclusions to be drawn. By its high degree of specificity, anti-aldo-3-oxime-BSA constitutes the most