Zobrazeno 1 - 10
of 20
pro vyhledávání: '"B. D. Morrison"'
Publikováno v:
Geoscientific Model Development, Vol 15, Pp 3233-3252 (2022)
The ability to monitor, understand, and predict the dynamics of the terrestrial carbon cycle requires the capacity to robustly and coherently synthesize multiple streams of information that each provide partial information about different pools and f
Externí odkaz:
https://doaj.org/article/f3d2bfffd6c2479187002f5b624f4717
Autor:
Maria A. Soos, Judith L. Treadway, Kenneth Siddle, Donald A. McClain, B D Morrison, Axel Ullrich, Jerrold M. Olefsky, Jeffrey E. Pessin
Publikováno v:
Scopus-Elsevier
Classical insulin and insulin-like growth factor I (IGF-I) receptors exist as well defined alpha 2 beta 2 heterotetrameric complexes that are assembled from two identical alpha beta heterodimeric half-receptor precursors. Recent evidence suggests tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddda9ca86e45b55326a2e349249f806a
https://doi.org/10.1073/pnas.88.1.214
https://doi.org/10.1073/pnas.88.1.214
Autor:
Jeffrey E. Pessin, B D Morrison, T O'Hare, Paul F. Pilch, John A. Wemmie, Judith L. Treadway, I Frias
Publikováno v:
Biochemical Journal. 271:99-105
Previous studies have indicated that turkey erythrocyte and rat liver membranes contain endogenous alpha beta heterodimeric insulin receptors in addition to the disulphide-linked alpha 2 beta 2 heterotetrameric complexes characteristic of most cell t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89d5b7a5e6cfb58e164841214e1791f7
https://doi.org/10.1042/bj2710099
https://doi.org/10.1042/bj2710099
Publikováno v:
Journal of Biological Chemistry. 262:6939-6942
To investigate the role of subunit communication in the insulin binding and tyrosine-specific protein kinase activities of the purified human placental insulin receptor, we have developed the methodology to isolate a functional alpha beta heterodimer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7c7808b333d03f8d3571b8cedaac71c
https://doi.org/10.1016/s0021-9258(18)48180-x
https://doi.org/10.1016/s0021-9258(18)48180-x
Publikováno v:
Journal of Biological Chemistry. 262:16730-16738
The dissociation of the purified human placental alpha 2 beta 2 heterotetrameric insulin receptor complex into an alpha beta heterodimeric state was found to occur in a pH- and dithiothreitol (DTT)-dependent manner. Formation of the alpha beta hetero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cac7636f3259e588be435565db048efd
https://doi.org/10.1016/s0021-9258(18)49316-7
https://doi.org/10.1016/s0021-9258(18)49316-7
Publikováno v:
Journal of Biological Chemistry. 264:21450-21453
Insulin and Mn/MgATP treatment of immunoaffinity-purified alpha beta heterodimeric insulin receptors induced the formation of an alpha 2 beta 2 heterotetrameric insulin receptor complex. In contrast, insulin-like growth factor-1 (IGF-1) treatment was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b31d0e6a8039d7cd673e7217d689cea
https://doi.org/10.1016/s0021-9258(20)88201-5
https://doi.org/10.1016/s0021-9258(20)88201-5
Publikováno v:
Biochemistry. 28:9734-9740
Examination of 125I-IGF-1 affinity cross-linking and beta-subunit autophosphorylation has indicated that IGF-1 induces a covalent association of isolated alpha beta heterodimeric IGF-1 receptors into an alpha 2 beta 2 heterotetrameric state, in a sim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce8bc78f82d9fcf2a7be60c887d8617b
https://doi.org/10.1021/bi00451a029
https://doi.org/10.1021/bi00451a029
Publikováno v:
Journal of Biological Chemistry. 263:7806-7813
The purified human placental alpha 2 beta 2 heterotetrameric insulin receptor complex was reduced and dissociated into functional alpha beta heterodimers by a combination of alkaline pH and dithiothreitol treatment. Insulin treatment of the isolated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::914bf446287214b3f989d59c0f5a929d
https://doi.org/10.1016/s0021-9258(18)68570-9
https://doi.org/10.1016/s0021-9258(18)68570-9
Publikováno v:
Endocrinology. 124:971-979
The purified human placental alpha 2 beta 2 heterotetrameric insulin-receptor complex was reduced and dissociated into functional alpha beta heterodimers by a combination of alkaline pH and dithiothreitol treatment. Wheat germ agglutinin (WGA) was ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd14b332fa0af28c18247345a7189062
https://doi.org/10.1210/endo-124-2-971
https://doi.org/10.1210/endo-124-2-971
Publikováno v:
Journal of Biological Chemistry. 264:9994-10001
We have extended these observations to examine the role of polylysine on the divalent metal ion requirement for ligand-stimulated protein kinase activity and the transmembrane signaling mechanism of both the human placenta insulin and insulin-like gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa60619b36d569f8fb36c3c1aed22bf5
https://doi.org/10.1016/s0021-9258(18)81758-6
https://doi.org/10.1016/s0021-9258(18)81758-6