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Simultaneous coupling of alpha 2-adrenergic receptors to two G-proteins with opposing effects. Subtype-selective coupling of alpha 2C10, alpha 2C4, and alpha 2C2 adrenergic receptors to Gi and Gs

Autor: Stephen B. Liggett, Hitoshi Kurose, M G Eason, B D Holt, John R. Raymond

Publikováno v: Journal of Biological Chemistry. 267:15795-15801

Coupling of the three alpha 2-adrenergic receptor (alpha 2AR) subtypes to Gi and Gs was studied in membranes from transfected CHO cells. We observed that in the presence of low concentrations of the alpha 2AR agonist UK-14304, alpha 2C10 mediated inh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::36e899b56b6204c7a5e238d80260db40
https://doi.org/10.1016/s0021-9258(19)49605-1

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Simultaneous coupling of alpha 2-adrenergic receptors to two G-proteins with opposing effects. Subtype-selective coupling of alpha 2C10, alpha 2C4, and alpha 2C2 adrenergic receptors to Gi and Gs

Autor: M G, Eason, H, Kurose, B D, Holt, J R, Raymond, S B, Liggett

Publikováno v: The Journal of biological chemistry. 267(22)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7ddc98c186d97e8108861609f28f8cee
https://pubmed.ncbi.nlm.nih.gov/1322406

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Beta 1- and beta 2-adrenergic receptors display subtype-selective coupling to Gs

Autor: S A, Green, B D, Holt, S B, Liggett

Publikováno v: Molecular pharmacology. 41(5)

beta-Adrenergic receptor (beta AR) subtypes differ in their affinities for some agonists and antagonists and thus may potentially impart different cellular effects based on this ligand-binding specificity. However, the possibility that there may be s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::12a88af09617e48e0f7168918ea66de5
https://pubmed.ncbi.nlm.nih.gov/1350321

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Determination of Hydrogen in Alkali Metals by Isotope Dilution Method

Autor: B. D. Holt

Publikováno v: Analytical Chemistry. 31:51-54

The rapid exchange of hydrogen and deuterium in sodium or NaK affords a convenient method for hydrogen determination in these metals. Spikes equivalent to 5 to 250 ppm of hydrogen were recovered on 2-gram samples with a standard deviation, from the q

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::43776f000327c766ceef30434c805e2e
https://doi.org/10.1021/ac60145a011

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Determination of Silicon by Distillation-Colorimetric Method

Autor: B. D. Holt

Publikováno v: Analytical Chemistry. 32:124-128

A method is described for the separation of microgram quantities of silicon from plutonium and other metals for colorimetric determination. The silicon is volatilized as the tetrafluoride from a perchloric acid solution in an allplutonium, uniformly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::146d05fc1c94e2189bc241cf4f472706
https://doi.org/10.1021/ac60157a037

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Chemical Engineering Division environmental chemistry annual report, July 1974--June 1975. [Chemistry of airborne particulates; /sup 18/O analysis of atmospheric sulfate aerosols; S emission control chemistry]

Autor: W. I. Wilson, Stanley Siegel, S. A. Johnson, F. A. Cafasso, B. D. Holt, L. Burris, P. T. Cunningham, B. R. Hubble

Analysis of ambient urban aerosols using infrared spectroscopic techniques has revealed the presence of acidic sulfate species. Field sampling has also revealed that the chemistry of submicrometer-sized particulates in different geographic regions is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cac004558186dabd3ebb7a0d19df484a
https://doi.org/10.2172/7176015

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