Zobrazeno 1 - 10
of 16
pro vyhledávání: '"B. D. Astill"'
Autor:
J. Hellwig, W. Mellert, K. Kuettler, B. D. Astill, D. Guest, R. L. Sielken, S. R. Murphy, T. R. Tyler, J. R. Hodgson, R. Gingell
Publikováno v:
Fundamental and Applied Toxicology. 31:29-41
2-Ethylhexanol (2EH) is a weak nongenotoxic hepatic peroxisome proliferator in the rat. It is a high-volume chemical intermediate in the preparation of the plasticizers bis-(2-ethylhexyl) adipate (DEHA), bis-(2-ethylhexyl) phthalate (DEHP), and tris-
Autor:
J. R. Hodgson, R. Gingell, Chr. Gembardt, W. Mellert, K. Deckardt, S. R. Murphy, B. D. Astill, T. R. Tyler, D. Guest
Publikováno v:
Toxicological Sciences. 29:31-39
Data on the subchronic toxicity of 2-ethylhexanol (2EH) were required to establish the dose vehicle and dose levels for oncogenicity studies. In preliminary studies 2EH was given subacutely (11 days) to male and female Fischer 344 rats and B6C3F1 mic
Autor:
J. R. Hodgson, D. Guest, B. D. Astill, R. W. Tyl, T. R. Tyler, R. Gingell, M. F. Kubena, S. R. Murphy, M. A. Vrbanic, L. C. Fisher
Publikováno v:
Fundamental and Applied Toxicology. 19:176-185
Undiluted 2-ethylhexanol (2-EH) was administered by occluded dermal application for 6 hr per day on Gestation Days 6 through 15 to pregnant Fischer 344 rats, in range-finding (R) and main (M) studies. The dermal route is considered to be the most rel
Autor:
R. W. TYL, L. C. FISHER, M. F. KUBENA, M. A. VRBANIC, R. GINGELL, D. GUEST, J. R. HODGSON, S. R. MURPHY, T. R. TYLER, B. D. ASTILL
Publikováno v:
Toxicological Sciences. 19:176-185
Autor:
E D, Barber, M, Cifone, J, Rundell, R, Przygoda, B D, Astill, E, Moran, A, Mulholland, E, Robinson, B, Schneider
Publikováno v:
Journal of applied toxicology : JAT. 20(1)
Eight phthalate esters, with alcohol chain lengths of 1-11 carbon atoms and with various degrees of branching, were tested in vitro in the L5178Y mouse lymphoma mammalian cell mutation assay and in the Balb/3T3 cell transformation assay. The tests we
Autor:
R W, Tyl, L C, Fisher, M F, Kubena, M A, Vrbanic, R, Gingell, D, Guest, J R, Hodgson, S R, Murphy, T R, Tyler, B D, Astill
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 19(2)
Undiluted 2-ethylhexanol (2-EH) was administered by occluded dermal application for 6 hr per day on Gestation Days 6 through 15 to pregnant Fischer 344 rats, in range-finding (R) and main (M) studies. The dermal route is considered to be the most rel
Autor:
D. W. Fassett, B. D. Astill, R. L. Roudabush, C. J. Terhaar, G. L. Wolf, K. Morgareidge, Walter J. Krasavage
Publikováno v:
Journal of the American Oil Chemists' Society. 52:53-58
The safety of monotertiarybutylhydroquinone as an oil-soluble food grade antioxidant was evaluated in acute studies with rats and dogs, in subacute feedings in rats, in rat reproductive efficiency and placental transfer studies, and in subacute feedi
Autor:
V. Boekelheide, B. D. Astill
Publikováno v:
Journal of the American Chemical Society. 77:4079-4084
Publikováno v:
Biochemical Journal. 90:194-201
Publikováno v:
Biochemical Journal. 75:543-551