Zobrazeno 1 - 10
of 62
pro vyhledávání: '"B. C. Tennant"'
Publikováno v:
Reproduction. 114:299-305
Testosterone and LH concentrations were determined in serum samples obtained before and 15 min after injections of GnRH (1 microgram kg-1) administered at 4-7 week intervals over 20 months to groups of male woodchucks (n = 6-7) born and maintained in
Autor:
R. F. Schinazi, B. H. Baldwin, Chung K. Chu, B. C. Tennant, Prabhu Rajagopalan, F. D. Boudinot
Publikováno v:
Antimicrobial Agents and Chemotherapy. 40:642-645
The woodchuck (Marmota monax) has proven to be a suitable animal model for studying hepatitis B virus (HBV) infection owing to similarities in the course of infection between woodchuck hepatitis virus (WHV) in woodchucks and HBV in humans. (-)-beta-L
The woodchuck hepatitis virus X gene is important for establishment of virus infection in woodchucks
Autor:
Rob Anderson, P. J. Cote, Rosina Girones, Shuichi Kaneko, W. E. Hornbuckle, Roger H. Miller, Hong-Shu Chen, John L. Gerin, Robert H. Purcell, B. C. Tennant
Publikováno v:
Scopus-Elsevier
All mammalian hepadnaviruses possess a gene, termed X, that encodes a protein capable of transactivating virus gene expression. The X gene overlaps the polymerase and precore genes as well as two newly identified open reading frames (ORFs) termed ORF
Publikováno v:
Molecular and Cellular Biology. 13:659-667
Woodchucks infected with woodchuck hepatitis virus (WHV) and ground squirrels infected with ground squirrel hepatitis virus (GSHV) both develop hepatocellular carcinoma (HCC), but WHV-associated tumors arise more frequently and much earlier in life.
Publikováno v:
Molecular and Cellular Biology. 13:659-667
Woodchucks infected with woodchuck hepatitis virus (WHV) and ground squirrels infected with ground squirrel hepatitis virus (GSHV) both develop hepatocellular carcinoma (HCC), but WHV-associated tumors arise more frequently and much earlier in life.
Publikováno v:
Molecular and Cellular Biology. 12:5336-5344
The woodchuck intronless proto-oncogene N-myc2 was initially discovered as a frequent target site for hepadnavirus integration in hepatocellular carcinoma. N-myc2 possesses characteristics of a functional retroposon derived from the woodchuck N-myc g
Autor:
P J Cote, B E Korba, H Steinberg, C Ramirez-Mejia, B Baldwin, W E Hornbuckle, B C Tennant, J L Gerin
Publikováno v:
The Journal of Immunology. 146:3138-3144
Immunosuppression is known to influence the state of chronic hepatitis B virus infection, and is thought to increase the risk of developing chronic infection in newly exposed individuals. Cyclosporin A (CsA), an immunosuppressive agent that inhibits
Autor:
Paul J. Cote, B C Tennant, John L. Gerin, B Baldwin, T L Brown, Frances V. Wells, Brent E. Korba, H Steinberg
Publikováno v:
Journal of Virology. 64:4499-4506
The kinetic patterns of woodchuck hepatitis virus (WHV) infection were monitored in the pancreas, kidneys, ovaries, and testes. Groups of woodchucks experimentally infected with a standardized inoculum of WHV were sacrificed at different times over a
Autor:
Michael C. Kew, P. J. Cote, B. C. Tennant, W. E. Hornbuckle, Roger H. Miller, Hong-Shu Chen, John L. Gerin, Robert H. Purcell
Publikováno v:
Journal of Virology. 66:5682-5684
A number of naturally occurring hepatitis B virus mutants that cannot synthesize the virus precore protein have been identified. Such mutants have been associated with more severe forms of hepatitis, including fulminant hepatitis. The most common mut
Publikováno v:
Antiviral therapy. 5(2)
Cell culture studies in our laboratory previously demonstrated synergistic antiviral activity for the combinations of lamivudine and a novel recombinant hybrid human alpha B/D interferon (rHu alpha B/D IFN) against hepatitis B virus (HBV) replication