Výsledky vyhledávání - "B. C. M. De Winter"

Highly Variable Paracetamol Pharmacokinetics After Multiple Oral Dosing in Frail Older People

Autor: L. T. van der Heijden, P. Mian, J. Hias, B. C. M. de Winter, J. Tournoy, L. Van der Linden, D. Tibboel, K. Walgraeve, J. Flamaing, B. C. P. Koch, K. Allegaert, I. Spriet

Publikováno v: Drugs and Aging, 39(1). ADIS INT LTD
Drugs and Aging, 39(1), 83-95. Adis

Introduction: Paracetamol pharmacokinetics (PK) is highly variable in older fit adults after intravenous administration. Frailty and oral administration likely result in additional variability. The aim was to determine oral paracetamol PK and variabi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d8fd6259e4cc83a2647ac577749560d
https://pure.eur.nl/en/publications/38f8124b-83fb-4250-8342-684e2cebc300

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Body composition is associated with tacrolimus pharmacokinetics in kidney transplant recipients

Autor: M. I. Francke, W. J. Visser, D. Severs, A. M. E. de Mik - van Egmond, D. A. Hesselink, B. C. M. De Winter

Publikováno v: European Journal of Clinical Pharmacology, 78(8), 1273-1287. Springer-Verlag

Purpose A population pharmacokinetic (popPK) model may be used to improve tacrolimus dosing and minimize under- and overexposure in kidney transplant recipients. It is unknown how body composition parameters relate to tacrolimus pharmacokinetics and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71db6696b3e48216c68114e5d781576e
https://pure.eur.nl/en/publications/3bb18425-7a2b-4b83-a50b-e0e164acc040

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Comparison of antipsychotic drug use among Dutch Youth before and after implementation of the Youth Act (2010–2019)

Autor: Y. Bais, R. A. Hermans, C. C. M. Schuiling-Veninga, H. J. Bos, S. M. Kloosterboer, B. C. M. de Winter, M. Simoons, G. C. Dieleman, M. H. J. Hillegers, B. C. P. Koch, B. Dierckx

Publikováno v: European Child and Adolescent Psychiatry. D. Steinkopff-Verlag

Objective The Dutch law on youth care (the Youth Act) was implemented from 2015 onwards. One of the government’s aims by implementing this new policy was de-medicalization of youths by separating youth mental healthcare from the rest of the healthc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9b8f3f6a35ec99867ff288dfe414e26
https://doi.org/10.1007/s00787-022-01949-0

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Comparison of antipsychotic drug use among Dutch Youth before and after implementation of the Youth Act (2010-2019)

Autor: Y, Bais, R A, Hermans, C C M, Schuiling-Veninga, H J, Bos, S M, Kloosterboer, B C M, de Winter, M, Simoons, G C, Dieleman, M H J, Hillegers, B C P, Koch, B, Dierckx

Publikováno v: European childadolescent psychiatry.

The Dutch law on youth care (the Youth Act) was implemented from 2015 onwards. One of the government's aims by implementing this new policy was de-medicalization of youths by separating youth mental healthcare from the rest of the healthcare system.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3e209ad07afe95a5fe611b2a12874977
https://pubmed.ncbi.nlm.nih.gov/35138475

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Personalized immunosuppression in elderly renal transplant recipients

Autor: Laura E J Peeters, T. van Gelder, B. C. M. de Winter, Dennis A. Hesselink, Louise M. Andrews

Publikováno v: Pharmacological Research, 130, 303-307. Academic Press

The number of elderly people has increased considerably over the last decades, due to a rising life expectancy and ageing populations. As a result, an increased number of elderly with end-stage-renal-disease are diagnosed, for which the preferred tre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b74d9badacb08f349243afddd34d8105
https://pure.eur.nl/en/publications/c68d7811-85ee-4c4b-8d73-bef9e219bd86

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Population pharmacokinetics of haloperidol in terminally ill adult patients

Autor: Linda G. Franken, Dick Tibboel, Ron A. A. Mathot, Anniek D. Masman, Frans P. M. Baar, Birgit C. P. Koch, T. van Gelder, B. C. M. de Winter

Publikováno v: European journal of clinical pharmacology, 73(10), 1271-1277. Springer Verlag
European Journal of Clinical Pharmacology, 73(10), 1271-1277. Springer-Verlag
European Journal of Clinical Pharmacology

Purpose: Over 80% of the terminally ill patients experience delirium in their final days. In the treatment of delirium, haloperidol is the drug of choice. Very little is known about the pharmacokinetics of haloperidol in this patient population. We t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffaa46d11f27030276128122acdc99ca
https://doi.org/10.1007/s00228-017-2283-6

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A population pharmacokinetic model to predict the individual starting dose of tacrolimus in adult renal transplant recipients

Autor: T. van Gelder, Nuria Lloberas, B. C. M. de Winter, Louise M. Andrews, Dennis A. Hesselink, J.W. de Fijter, R.H.N. van Schaik, D J A R Moes, Laure Elens

Publikováno v: British Journal of Clinical Pharmacology, 85(3), 601-615
British Journal of Clinical Pharmacology, 85(3), 601-615. Wiley-Blackwell Publishing Ltd
British Journal of Clinical Pharmacology
Dipòsit Digital de la UB
Universidad de Barcelona
British Journal of Clinical Pharmacology, (2018)

Aims The aims of this study were to describe the pharmacokinetics of tacrolimus immediately after kidney transplantation, and to develop a clinical tool for selecting the best starting dose for each patient. Methods Data on tacrolimus exposure were c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0312d35dc9ca49a00933f57582662d88
http://hdl.handle.net/1887/120031

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Population pharmacokinetic modelling of intravenous paracetamol in fit older people displays extensive unexplained variability

Autor: Mirko Petrovic, Klaus T. Olkkola, Karel Allegaert, Dick Tibboel, Paola Mian, B.C.P. Koch, M. J. van Esdonk, Antti Liukas, Isabel Spriet, B. C. M. de Winter

Publikováno v: British Journal of Clinical Pharmacology, 85(1), 126-135. Wiley-Blackwell Publishing Ltd

AIMS: Paracetamol is the analgesic most used by older people. The physiological changes occurring with ageing influence the pharmacokinetics (PK) of paracetamol and its variability. We performed a population PK-analysis to describe the PK of intraven

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73ed749dfe208b871a43c89ad8aa61c7
https://pure.eur.nl/en/publications/ab611c04-4c6a-4161-a657-f822152642ba

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Pharmacokinetic considerations and recommendations in palliative care, with focus on morphine, midazolam and haloperidol

Autor: L. van Zuylen, T. van Gelder, Linda G. Franken, Frans P. M. Baar, Birgit C. P. Koch, H J van Esch, B. C. M. de Winter, Ron A. A. Mathot, Dick Tibboel

Publikováno v: Expert Opinion on Drug Metabolism & Toxicology, 12(6), 669-680. Taylor & Francis Ltd

Introduction: A variety of medications are used for symptom control in palliative care, such as morphine, midazolam and haloperidol. The pharmacokinetics of these drugs may be altered in these patients as a result of physiological changes that occur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ed8c9a3717d913c7c81a116e12c003
https://pure.eur.nl/en/publications/59802145-7eeb-4be7-8225-e7a9000b308b

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