Zobrazeno 1 - 10
of 773
pro vyhledávání: '"B. Bull"'
Autor:
Yu-Chung Lin, Jennifer D. Brooks, Shelley B. Bull, France Gagnon, Celia M. T. Greenwood, Rayjean J. Hung, Jerald Lawless, Andrew D. Paterson, Lei Sun, Lisa J. Strug, On behalf of the Genetic Epidemiology Committee of the Canadian COVID Genomics Network (CanCOGeN) HostSeq Project
Publikováno v:
Genome Medicine, Vol 12, Iss 1, Pp 1-8 (2020)
Abstract The identification of genetic variation that directly impacts infection susceptibility to SARS-CoV-2 and disease severity of COVID-19 is an important step towards risk stratification, personalized treatment plans, therapeutic, and vaccine de
Externí odkaz:
https://doaj.org/article/3c7133d3fd634af29522cd90bec1df2a
Autor:
Thi H. O. Nguyen, Carolyn A. Cohen, Louise C. Rowntree, Maireid B. Bull, Asmaa Hachim, Katherine Kedzierska, Sophie A. Valkenburg
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
T cell responses are a key cornerstone to viral immunity to drive high-quality antibody responses, establishing memory for recall and for viral clearance. Inefficient recruitment of T cell responses plays a role in the development of severe COVID-19
Externí odkaz:
https://doaj.org/article/bc9ee59db72b419eb4d06a615c8602be
Autor:
Changchang Xu, Shelley B. Bull
Publikováno v:
Statistics in Medicine. 42:2134-2161
Autor:
Jay S. Wunder, Minji J. Lee, Junghyun Nam, Beatrice Y. Lau, Brendan C. Dickson, Dushanthi Pinnaduwage, Shelley B. Bull, Peter C. Ferguson, Andrew Seto, Nalan Gokgoz, Irene L. Andrulis
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Immune checkpoint proteins, such as PD-L1 and PD-1, are important in several cancers; however, their role in osteosarcoma (OSA) and soft tissue sarcoma (STS) remains unclear. Our aims were to determine whether subsets of OSA/STS harbor tumor-infiltra
Externí odkaz:
https://doaj.org/article/0026928f059a4331a52a64db61b3b10a
Publikováno v:
BMC Proceedings, Vol 12, Iss S9, Pp 181-186 (2018)
Abstract Background There has been significant interest in investigating genome-wide and epigenome-wide associations with lipids. Testing at the gene or region level may improve power in such studies. Methods We analyze chromosome 11 cytosine-phospha
Externí odkaz:
https://doaj.org/article/a7eac26c64644f4ba7be8cec1f70f13f
Publikováno v:
Viruses, Vol 13, Iss 9, p 1779 (2021)
Next generation influenza vaccines that target conserved epitopes are becoming a clinical reality but still have challenges to overcome. Universal next generation vaccines are considered a vital tool to combat future pandemic viruses and have the pot
Externí odkaz:
https://doaj.org/article/41e92cf05666478a8a19cda4d1b10f5d
Autor:
Irene L. Andrulis, Shelley B. Bull, Sandrine Tchatchou, Dushanthi Pinnaduwage, Anna Marie Mulligan
We previously observed T-bet+ lymphocytes to be associated with a good prognosis in a cohort of women with familial breast cancer. To validate this finding, we evaluated lymphocyte T-bet expression in an independent unselected prospectively accrued s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc6578dd7afd0745b99d9cd1932a6c43
https://doi.org/10.1158/2326-6066.c.6548386.v1
https://doi.org/10.1158/2326-6066.c.6548386.v1
Autor:
Irene L. Andrulis, Shelley B. Bull, Sandrine Tchatchou, Dushanthi Pinnaduwage, Anna Marie Mulligan
Table S1 gives the relative risks by univariate Cox proportional hazards model of DFS for di- categorization (low, high) of T-bet for several (10, 15, 20, 25, 30) cut points. T-bet-/low was associated with reduced DFS at cut points 15, 25, and 30 as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04ad007b368b7da7099f64f034b344fe
https://doi.org/10.1158/2326-6066.22537297
https://doi.org/10.1158/2326-6066.22537297
Autor:
Irene L. Andrulis, Shelley B. Bull, Sandrine Tchatchou, Dushanthi Pinnaduwage, Anna Marie Mulligan
This figure compares K-M curves of DFS by di- and tri- categorizations of T-bet for several (10, 15, 20, 25,) cut points. It is evident in the three-level KM plots that the absent and low count groups of T-bet are indistinguishable for the cut-points
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::134f69bbbc383ae56f4f12ede19aad6c
https://doi.org/10.1158/2326-6066.22537300
https://doi.org/10.1158/2326-6066.22537300
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