Zobrazeno 1 - 10
of 473
pro vyhledávání: '"B. Bradshaw"'
Autor:
Shreyas Balaji, Taylor J. Woodward, Emily Richter, Arnold Chang, Richard Otiz, Praveen P. Kulkarni, Kaashyap Balaji, Heather B. Bradshaw, Craig F. Ferris
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
The present studies were undertaken to understand the effects of the commonly used nutraceutical PEA on brain function and lipid chemistry. These studies using MRI and broad-scale lipidomics are without precedent in animal or human research. During t
Externí odkaz:
https://doaj.org/article/484aa0118d7f4f92940aac8659ec8a1e
Autor:
Aymen H. Sadaka, Justin Canuel, Marcelo Febo, Clare T. Johnson, Heather B. Bradshaw, Richard Ortiz, Federica Ciumo, Praveen Kulkarni, Michael A. Gitcho, Craig F. Ferris
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
With the recent legalization of inhaled cannabis for medicinal and recreational use, the elderly represents one of the newest, rapidly growing cohorts of cannabis users. To understand the neurobiological effects of cannabis on the aging brain, 19–2
Externí odkaz:
https://doaj.org/article/1339d5ce7288463dbaddb5836778a52b
Autor:
Aymen H. Sadaka, Ana G. Ozuna, Richard J. Ortiz, Praveen Kulkarni, Clare T. Johnson, Heather B. Bradshaw, Bruce S. Cushing, Ai-Ling Li, Andrea G. Hohmann, Craig F. Ferris
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-16 (2021)
Abstract Background The phytocannabinoid cannabidiol (CBD) exhibits anxiolytic activity and has been promoted as a potential treatment for post-traumatic stress disorders. How does CBD interact with the brain to alter behavior? We hypothesized that C
Externí odkaz:
https://doaj.org/article/f485f7eb3333468a9b1e8597a6b74aad
Publikováno v:
BBA Advances, Vol 2, Iss , Pp 100054- (2022)
Maternal cannabis use during lactation may expose developing infants to cannabinoids (CBs) such as ∆-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). CBs modulate lipid signaling molecules in the central nervous system in age- and cell-dependent
Externí odkaz:
https://doaj.org/article/6c288daf76e14bd484f72a0a9da89e0d
Autor:
Daniel I. Brierley, Joe R. Harman, Natasha Giallourou, Emma Leishman, Anna Emily Roashan, Ben A.D. Mellows, Heather B. Bradshaw, Jonathan R. Swann, Ketan Patel, Benjamin J. Whalley, Claire M. Williams
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 10, Iss 4, Pp 844-859 (2019)
Abstract Background Muscle wasting, anorexia, and metabolic dysregulation are common side‐effects of cytotoxic chemotherapy, having a dose‐limiting effect on treatment efficacy, and compromising quality of life and mortality. Extracts of Cannabis
Externí odkaz:
https://doaj.org/article/db29cdbd0a4e4245b9247006c7c1688e
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Endocannabinoids (eCBs) and transient receptor potential (TRP) channels are associated with thermoregulation; however, there are many gaps in the understanding of how these signaling systems work together in responding to changes in temperature. TRPV
Externí odkaz:
https://doaj.org/article/53962555b98a4cdeb8b0a29681a5a59a
Autor:
Takaaki, Sokabe, Heather B, Bradshaw, Makoto, Tominaga, Emma, Leishman, Avinash, Chandel, Craig, Montell
Publikováno v:
Science signaling. 15(755)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7b779efe20acfbab2ef90bcf0b3bab26
https://pubmed.ncbi.nlm.nih.gov/36219683
https://pubmed.ncbi.nlm.nih.gov/36219683
Autor:
Emma Leishman, Phillip E. Kunkler, Meera Manchanda, Kishan Sangani, Jordyn M. Stuart, Gerry S. Oxford, Joyce H. Hurley, Heather B. Bradshaw
Publikováno v:
Neurobiology of Pain, Vol 1, Iss , Pp 28-36 (2017)
Exposure to airborne toxins can trigger headaches, but the mechanisms are not well understood. Some environmental toxins, such as acrolein, activate transient receptor potential ankyrin 1 (TRPA1), a receptor involved in pain sensation that is highly
Externí odkaz:
https://doaj.org/article/08d01adae96f4e5680e682c6fa6bd485
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Derived from arachidonic acid (AA), the endogenous cannabinoid (eCB) 2-arachidonoyl glycerol (2-AG) is a substrate for α/β hydrolase domain-12 (ABHD12). Loss-of-function mutations of ABHD12 are associated with the neurodegenerative disorder polyneu
Externí odkaz:
https://doaj.org/article/dec61f0d1d3d4058acf4818a46ea59b7
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