Zobrazeno 1 - 10
of 156
pro vyhledávání: '"B. Birk"'
Autor:
Rasmus Kjøbsted, Jonas M. Kristensen, Nicolas O. Eskesen, Kohei Kido, Klara Fjorder, Ditte F. Damgaard, Jeppe K. Larsen, Nicoline R. Andersen, Jesper B. Birk, Anders Gudiksen, Jonas T. Treebak, Peter Schjerling, Henriette Pilegaard, Jørgen F. P. Wojtaszewski
Publikováno v:
Kjøbsted, R, Kristensen, J M, Eskesen, N O, Kido, K, Fjorder, K, Damgaard, D F, Larsen, J K, Andersen, N R, Birk, J B, Gudiksen, A, Treebak, J T, Schjerling, P, Pilegaard, H & Wojtaszewski, J 2023, ' TBC1D4-S711 controls skeletal muscle insulin sensitization after exercise and contraction ', Diabetes, vol. 72, no. 7, pp. 857-871 . https://doi.org/10.2337/db22-0666
The ability of insulin to stimulate glucose uptake in skeletal muscle is important for whole-body glycemic control. Insulin-stimulated skeletal muscle glucose uptake is improved in the period after a single bout of exercise and accumulating evidence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a89498ca981548113ae9d2d065d9355c
https://curis.ku.dk/ws/files/344709125/Kjobsted_et_al_Diabetes_2023_TBC1D4_S711A_manuscript_Submitted_version_.pdf
https://curis.ku.dk/ws/files/344709125/Kjobsted_et_al_Diabetes_2023_TBC1D4_S711A_manuscript_Submitted_version_.pdf
Autor:
Amy Zheng, Seong Eun Kwak, Jesper B Birk, Edward B Arias, Dominic Thorley, Jørgen F P Wojtaszewski, Gregory D Cartee
Publikováno v:
The journals of gerontology. Series A, Biological sciences and medical sciences.
AMP-activated protein kinase (AMPK), a highly conserved, heterotrimeric serine/threonine kinase with critical sensory and regulatory functions, is proposed to induce antiaging actions of caloric restriction (CR). Although earlier studies assessed CR
AXIN1 knockout does not alter AMPK/mTORC1 regulation and glucose metabolism in mouse skeletal muscle
Autor:
Thomas E. Jensen, Zhencheng Li, Fabien Le Grand, Anika Offergeld, Jonas R. Knudsen, Jørgen F. P. Wojtaszewski, Peter Schjerling, Carlos Henríquez-Olguín, Jingwen Li, Kaspar W. Persson, Ylva Hellsten, William Jarassier, Jesper B. Birk
Publikováno v:
The Journal of Physiology. 599:3081-3100
Key points Tamoxifen-inducible skeletal muscle-specific AXIN1 knockout (AXIN1 imKO) in mouse does not affect whole-body energy substrate metabolism. AXIN1 imKO does not affect AICAR or insulin-stimulated glucose uptake in adult skeletal muscle AXIN1
Akademický článek
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Autor:
Rasmus Kjøbsted, Jonas M. Kristensen, Jesper B. Birk, Nicolas O. Eskesen, Kohei Kido, Nicoline R. Andersen, Jeppe K. Larsen, Marc Foretz, Benoit Viollet, Flemming Nielsen, Kim Brøsen, Niels Jessen, Ylva Hellsten, Kurt Højlund, Jørgen F.P. Wojtaszewski
SummaryMetformin is an inexpensive oral anti-hyperglycemic agent used worldwide as a first-choice drug for the prevention of type 2 diabetes mellitus (T2DM). Although current view suggests that metformin exerts its anti-hyperglycemic effect by loweri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e95a9495b2bdc5f282894c8631445658
https://doi.org/10.1101/2022.05.22.492936
https://doi.org/10.1101/2022.05.22.492936
Autor:
Grit Elster, Christina Pedersen Bønding, Nanna Skytt Pilmark, Jesper B. Birk, Henriette Pilegaard, Laura Oberholzer, Mark Lyngbæk, Katrine B. Hansen, Niels Frederich Holm, Anne-Kristine Meinild-Lundby, Ida Elkjær, Jonas M. Kristensen, Emil List Larsen, Henrik E. Poulsen, Kristian Karstoft, Christoph Siebenmann, Bente Klarlund Pedersen, Jens Frey Halling, Jørgen F. P. Wojtaszewski
Publikováno v:
Pilmark, N S, Oberholzer, L, Halling, J F, Kristensen, J M, Bønding, C P, Elkjær, I, Lyngbæk, M, Elster, G, Siebenmann, C, Holm, N F, Birk, J B, Larsen, E L, Meinild-Lundby, A-K, Wojtaszewski, J, Pilegaard, H, Poulsen, H, Pedersen, B K, Hansen, K B & Karstoft, K 2022, ' Skeletal muscle adaptations to exercise are not influenced by metformin treatment in humans: secondary analyses of 2 randomised, clinical trials ', Applied Physiology, Nutrition and Metabolism, vol. 47, no. 3, pp. 309-320 . https://doi.org/10.1139/apnm-2021-0194
Metformin and exercise both improve glycemic control, but in vitro studies have indicated that an interaction between metformin and exercise occurs in skeletal muscle, suggesting a blunting effect of metformin on exercise training adaptations. Two st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e72b3fa25c13df8b4484382bf5927e8
https://curis.ku.dk/ws/files/284840726/Pilmark_et_al_Applied_Physiology_Nutrition_and_Metabolism_2021_0194_Accepted_manuscript_.pdf
https://curis.ku.dk/ws/files/284840726/Pilmark_et_al_Applied_Physiology_Nutrition_and_Metabolism_2021_0194_Accepted_manuscript_.pdf
Autor:
P. Wilhelmi, V. Giri, S. Henkes, T. Walk, V. Haake, S. Scholz, W. Busch, M. Barenys, F. Zickgraf, R. Landsiedel, D. Funk-Weyer, B. Birk, B. Flick
Publikováno v:
Toxicology Letters. 368:S252
Akademický článek
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Akademický článek
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Autor:
Rasmus Kjøbsted, Nicolas O. Jørgensen, Ylva Hellsten, Jesper B. Birk, Jørgen F. P. Wojtaszewski, Jeppe Kjærgaard Larsen, Kohei Kido
Publikováno v:
Kjøbsted, R, Kido, K, Larsen, J K, Jørgensen, N O, Birk, J B, Hellsten, Y & Wojtaszewski, J 2021, ' Measurement of insulin-and contraction-stimulated glucose uptake in isolated and incubated mature skeletal muscle from mice ', Journal of Visualized Experiments, no. 171, e61398 . https://doi.org/10.3791/61398
Skeletal muscle is an insulin-responsive tissue and typically takes up most of the glucose that enters the blood after a meal. Moreover, it has been reported that skeletal muscle may increase the extraction of glucose from the blood by up to 50-fold