Zobrazeno 1 - 10
of 16
pro vyhledávání: '"B. Ben Koff"'
Autor:
Aditya Banerjee, Chia-Yu Kang, Minjun An, B. Ben Koff, Sham Sunder, Anuj Kumar, Livia M. A. Tenuta, Randy B. Stockbridge
Publikováno v:
mBio, Vol 15, Iss 5 (2024)
ABSTRACTMicroorganisms resist fluoride toxicity using fluoride export proteins from one of several different molecular families. Cariogenic species Streptococcus mutans and Candida albicans extrude intracellular fluoride using a CLCF F-/H+ antiporter
Externí odkaz:
https://doaj.org/article/e33318f0947d42c08a2844089bbbc133
Autor:
Ali A. Kermani, Christian B. Macdonald, Olive E. Burata, B. Ben Koff, Akiko Koide, Eric Denbaum, Shohei Koide, Randy B. Stockbridge
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Gdx-Clo is a bacterial transporter from the small multidrug resistance (SMR) family. Here, the authors use solid supported membrane electrophysiology to characterize Gdx-Clo functionally and report crystal structures of Gdx-Clo which confirm the dual
Externí odkaz:
https://doaj.org/article/d4785d992fee4f28884dcfc5aaeb641b
Publikováno v:
eLife, Vol 11 (2022)
Proteins from the bacterial small multidrug resistance (SMR) family are proton-coupled exporters of diverse antiseptics and antimicrobials, including polyaromatic cations and quaternary ammonium compounds. The transport mechanism of the Escherichia c
Externí odkaz:
https://doaj.org/article/cc3ac98bd2e3424682e09d21aa8905a9
Publikováno v:
eLife, Vol 10 (2021)
Fluc family fluoride channels protect microbes against ambient environmental fluoride by undermining the cytoplasmic accumulation of this toxic halide. These proteins are structurally idiosyncratic, and thus the permeation pathway and mechanism have
Externí odkaz:
https://doaj.org/article/c090bf80bcab49db8a9299562aecdb5b
Autor:
B. Ben Koff, Christian B. Macdonald, Shohei Koide, Ali A. Kermani, Eric Denbaum, Akiko Koide, Randy B. Stockbridge, Olive E. Burata
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Nature Communications
Nature Communications
By providing broad resistance to environmental biocides, transporters from the small multidrug resistance (SMR) family drive the spread of multidrug resistance cassettes among bacterial populations. A fundamental understanding of substrate selectivit
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Fluc family fluoride channels protect microbes against ambient environmental fluoride by undermining the cytoplasmic accumulation of this toxic halide. These proteins are structurally idiosyncratic, and thus the permeation pathway and mechanism have
Autor:
Randy B. Stockbridge, Gwo-Yu Chuang, Alexander R. Davis, Benjamin C. McIlwain, Yen-Ting Lai, Louise Chang, Amanda L. Erwin, Tatsiana Bylund, Peter D. Kwong, B. Ben Koff, Melanie D. Ohi
Publikováno v:
J Mol Biol
Structural studies of membrane proteins, especially small membrane proteins, are associated with well-known experimental challenges. Complexation with monoclonal antibody fragments is a common strategy to augment such proteins; however, generating an
Akademický článek
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