Zobrazeno 1 - 10
of 38
pro vyhledávání: '"B. B. Lorenzetti"'
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 86, Pp 133-136 (1991)
Ammonium salt derivatives of natural allylphenols were synthesized with the purpose of obtaining potential peripheral analgesics. These drugs, by virtue of their physicochemical properties, would not be able to cross the blood brain barrier. Their in
Externí odkaz:
https://doaj.org/article/df3751d9c97d49209185577fd2ffade6
Publikováno v:
British Journal of Pharmacology. 141:1175-1184
1. This study characterises some of the mechanisms and mediators involved in the orofacial nociception triggered by injection of formalin into the upper lip of the rat, by assessing the influence of various treatments on behavioural nociceptive respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4222191eb7f772fdd94a7cb32ee48a18
https://doi.org/10.1038/sj.bjp.0705724
https://doi.org/10.1038/sj.bjp.0705724
Publikováno v:
British Journal of Pharmacology. 126:649-656
The effects of BK agonists and antagonists, and other hyperalgesic/antihyperalgesic drugs were measured (3 h after injection of hyperalgesic drugs) in a model of mechanical hyperalgesia (the end-point of which was indicated by a brief apnoea, the ret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b52e3085ccd7301ca11cfd92bd7bbef2
https://doi.org/10.1038/sj.bjp.0702347
https://doi.org/10.1038/sj.bjp.0702347
Publikováno v:
British Journal of Pharmacology. 126:45-50
1. The effect of interleukin-10 (IL-10) upon the hyperalgesic activities in rats of bradykinin, tumor necrosis factor alpha (TNF alpha), interleukin-1 beta (IL-1 beta), interleukin-6 (IL-6), interleukin-8 (IL-8), prostaglandin E2 (PGE2) and carrageen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3f24c4415ef7fc31f90b0a10a051cd0
https://doi.org/10.1038/sj.bjp.0702266
https://doi.org/10.1038/sj.bjp.0702266
Publikováno v:
British Journal of Pharmacology. 110:1227-1231
1. The hyperalgesic activities in rats of bradykinin, carrageenin and lipopolysaccharide (LPS) were investigated in a model of mechanical hyperalgesia. 2. Bradykinin and carrageenin evoked dose-dependent hyperalgesia with maximum responses of similar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e03794dad5f08a133daf60327b1ac9a
https://doi.org/10.1111/j.1476-5381.1993.tb13946.x
https://doi.org/10.1111/j.1476-5381.1993.tb13946.x
Publikováno v:
British Journal of Pharmacology. 107:660-664
1. The hyperalgesic activities in rats of interleukin-1 beta (IL-1 beta), IL-6, IL-8, tumour necrosis factor alpha (TNF alpha) and carrageenin were investigated. 2. IL-6 activated the previously delineated IL-1/prostaglandin hyperalgesic pathway but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29d3ab38bd51e9f962bdd8e81519760e
https://doi.org/10.1111/j.1476-5381.1992.tb14503.x
https://doi.org/10.1111/j.1476-5381.1992.tb14503.x
Publikováno v:
British Journal of Pharmacology. 106:489-492
1. The hyperalgesic effects of interleukin-1 beta (IL-1 beta) and prostaglandin E2 (PGE2) were measured in rats. 2. Hyperalgesic responses to IL-1 beta were inhibited in a dose-dependent manner by alpha-melanocyte stimulating hormone (alpha-MSH)-rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a855bf53e80db075ee05c90032b5c855
https://doi.org/10.1111/j.1476-5381.1992.tb14361.x
https://doi.org/10.1111/j.1476-5381.1992.tb14361.x
Autor:
Fernando Q. Cunha, Djane Braz Duarte, B B Lorenzetti, Mani Indiana Funez, Sérgio H. Ferreira, Carlos Amílcar Parada, Luiz F. Ferrari, Daniela Sachs
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 105(49)
Previous work from our group showed that intrathecal (i.t.) administration of substances such as glutamate, NMDA, or PGE 2 induced sensitization of the primary nociceptive neuron (PNN hypernociception) that was inhibited by a distal intraplantar (i.p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e094974b169e032858729836c32f49d9
https://pubmed.ncbi.nlm.nih.gov/18799742
https://pubmed.ncbi.nlm.nih.gov/18799742
Publikováno v:
Agents and Actions. 38:C7-C9
Using specific antisera for IL-1 beta and IL-8, as well as cyclooxygenase inhibitors and propranolol, we have demonstrated that these cytokines are responsible for the prostaglandin and sympathetic components of carrageenin-induced hyperalgesia in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e36e1053923aed7d4248c08720f58c7
https://doi.org/10.1007/bf01991120
https://doi.org/10.1007/bf01991120
Publikováno v:
European cytokine network. 12(2)
The effect of interleukin-13 (IL-13) on hyperalgesic responses to intraplantar (i.pl.) injection of carrageenin, E. coli endotoxin (LPS), bradykinin, tumour necrosis factor a (TNF-alpha), interleukin-1 beta (IL-1 beta), interleukin-8 (IL-8) and prost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::668ac470344edce0a3c76cf8b2ebc9dc
https://pubmed.ncbi.nlm.nih.gov/11399514
https://pubmed.ncbi.nlm.nih.gov/11399514