Zobrazeno 1 - 10
of 240
pro vyhledávání: '"B. B. Hoffman"'
Autor:
S B, Martins, S, Lai, S, Tu, R, Shankar, S N, Hastings, B B, Hoffman, N, Dipilla, M K, Goldstein
Publikováno v:
AMIA ... Annual Symposium proceedings. AMIA Symposium.
ATHENA-HTN is a clinical decision support system (CDSS) that delivers guideline-based patient-specific recommendations about hypertension management at the time of clinical decision-making. The ATHENA-HTN knowledge is stored in a knowledge-base (KB).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::26ea136aba111f3dc2225ba264f3fac1
https://pubmed.ncbi.nlm.nih.gov/17238399
https://pubmed.ncbi.nlm.nih.gov/17238399
Autor:
A S, Chan, R W, Coleman, S B, Martins, A, Advani, M A, Musen, H B, Bosworth, E Z, Oddone, M G, Shlipak, B B, Hoffman, M K, Goldstein
Publikováno v:
Studies in health technology and informatics. 107(Pt 1)
Measurement of provider adherence to a guideline-based decision support system (DSS) presents a number of important challenges. Establishing a causal relationship between the DSS and change in concordance requires consideration of both the primary in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3fe1ec7854a181a90e04caf3cdbe076c
https://pubmed.ncbi.nlm.nih.gov/15360788
https://pubmed.ncbi.nlm.nih.gov/15360788
Autor:
B B, Hoffman, Z W, Hu
Publikováno v:
The Prostate. Supplement. 9
Smooth muscle cells in vascular tissue, like tissue within the urogenital sinus, undergo growth and proliferation.This review attempts to compare and contrast the mechanisms and controlling factors involved in prostatic and vascular tissue. There is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a8d5d492d9c66cc60c74af52ce59aa20
https://pubmed.ncbi.nlm.nih.gov/11056500
https://pubmed.ncbi.nlm.nih.gov/11056500
Autor:
Z W, Hu, B B, Hoffman
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 126
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b701f0b0dfac73aae06eec3fb586bd59
https://pubmed.ncbi.nlm.nih.gov/10685409
https://pubmed.ncbi.nlm.nih.gov/10685409
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 290(1)
Signaling pathways of many G protein-coupled receptors overlap with those of receptor tyrosine kinases. We have found previously that alpha1-adrenergic receptors stimulate DNA synthesis and cell proliferation in human vascular smooth muscle cells; th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dcdb9950b49ba84398f1ee5ff08e3d1a
https://pubmed.ncbi.nlm.nih.gov/10381756
https://pubmed.ncbi.nlm.nih.gov/10381756
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 289(3)
alpha1-Adrenergic receptors mediate mitogenic responses and increase intracellular free Ca2+ ([Ca2+]i) in vascular smooth muscle cells. Induction of c-fos is a critical early event in cell growth; expression of this gene is regulated by a number of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aa9133e79ab27a6b3667ab7be8e0e8ff
https://pubmed.ncbi.nlm.nih.gov/10336529
https://pubmed.ncbi.nlm.nih.gov/10336529
Autor:
J M, Thomas, B B, Hoffman
Publikováno v:
Molecular pharmacology. 49(5)
Many different types of cells develop increased adenylyl cyclase activity (sensitization) on prior treatment with drugs such as opiates that acutely inhibit the enzyme. We found that human embryonic kidney (HEK) 293 m2 cells, which express the inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5f8893535992f8b5191b1a986fbb69d7
https://pubmed.ncbi.nlm.nih.gov/8622641
https://pubmed.ncbi.nlm.nih.gov/8622641
Publikováno v:
The Journal of biological chemistry. 271(15)
Activation of alpha1 adrenergic receptors stimulates mitogenesis in human vascular smooth muscle cells (HVSMCs). To examine signaling pathways by which activation of alpha1 receptors may induce mitogenesis in HVSMCs, we have found that alpha1 recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d1abc157b217eb11643f130f8114ac0b
https://pubmed.ncbi.nlm.nih.gov/8621543
https://pubmed.ncbi.nlm.nih.gov/8621543
Publikováno v:
Receptorssignal transduction. 6(3-4)
The role of the endothelium in modulating smooth muscle cell growth is unclear. alpha 1 adrenergic receptors activate proto-oncogene expression in smooth muscle. We have now found in rat aorta that carbachol, a muscarinic cholinergic agonist that pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::67965e7ac2a462c64de7e7f0c798fda6
https://pubmed.ncbi.nlm.nih.gov/9259051
https://pubmed.ncbi.nlm.nih.gov/9259051
Publikováno v:
Molecular pharmacology. 48(4)
Alterations in adenylyl cyclase activity in cultured cells after prolonged exposure to drugs such as morphine have been extensively studied as models for drug tolerance and withdrawal. NG108-15 cells develop increased intracellular cAMP concentration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::56203b7a1f55a17b6a8c5e06aff0e44f
https://pubmed.ncbi.nlm.nih.gov/7476883
https://pubmed.ncbi.nlm.nih.gov/7476883