Zobrazeno 1 - 10
of 117
pro vyhledávání: '"B. B. Aggarwal"'
Autor:
B. B. Aggarwal
Publikováno v:
Acta Horticulturae. :33-46
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70a91f21bac248da3ddbbf9e84e0d1f0
https://doi.org/10.17660/actahortic.2009.841.1
https://doi.org/10.17660/actahortic.2009.841.1
Publikováno v:
Leukemia. 17:2196-2201
Epstein-Barr virus (EBV)-immortalized lymphoblastoid cells express high levels of lymphotoxin and use this molecule as an autocrine growth factor. We hypothesized that the EBV-derived latent membrane protein 1 (LMP1) mediates lymphotoxin production b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36e9ee59fcb02d82d588a2e2c918d487
https://doi.org/10.1038/sj.leu.2403130
https://doi.org/10.1038/sj.leu.2403130
Publikováno v:
The Journal of Immunology. 157:2410-2417
Human TNF is a highly pleiotropic cytokine that mediates its effects by binding to two distinct receptors, viz p60 and p80, which transmit their signals independently of each other. Activation of the transcription factor NF-kappa B is one of the earl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a152c18a7189ee40eb955157215c30e9
https://doi.org/10.4049/jimmunol.157.6.2410
https://doi.org/10.4049/jimmunol.157.6.2410
Publikováno v:
The Journal of Immunology. 157:297-304
Previously we have shown that treatment of ML-1a cells with TNF in the presence of cycloheximide triggers apoptosis within 90 min. In the present report we used this system to investigate the role of ceramide in TNF action. We found that while maximu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::296750b29f29ac10a656ce7debaa613a
https://doi.org/10.4049/jimmunol.157.1.297
https://doi.org/10.4049/jimmunol.157.1.297
Autor:
L Zhang, B B Aggarwal
Publikováno v:
The Journal of Immunology. 153:3745-3754
The interaction of different polypeptide growth factors with their cell surface receptors, which are typically rich in cysteine, is modulated by sulfhydryl (SH) reagents. Because the extracellular domain of both human TNFRs are likewise rich in cyste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86bcdada717fe06599f495b068b09f45
https://doi.org/10.4049/jimmunol.153.8.3745
https://doi.org/10.4049/jimmunol.153.8.3745
Publikováno v:
The Journal of Immunology. 153:2248-2257
TNF binds to two distinct receptors designated p60 and p80. Because Abs to the p60 receptor (anti-p60) can mimic TNF, we therefore compared the cellular signaling of TNF with that of anti-p60. We demonstrate both qualitative and quantitative differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30eb918cf081efbda6ab5233a84f3284
https://doi.org/10.4049/jimmunol.153.5.2248
https://doi.org/10.4049/jimmunol.153.5.2248
Autor:
M Higuchi, B B Aggarwal
Publikováno v:
The Journal of Immunology. 152:4017-4025
Two different types of TNF receptors, the p60 receptor with a molecular mass of 60 kDa and the p80 receptor with a mass of 80 kDa, have been identified. TNF exhibits a wide variety of biologic actions, but which receptor is responsible for these biol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a96b898ec660c9031aaabd32e3f98bef
https://doi.org/10.4049/jimmunol.152.8.4017
https://doi.org/10.4049/jimmunol.152.8.4017
Autor:
M Higuchi, B B Aggarwal
Publikováno v:
The Journal of Immunology. 152:3550-3558
As is true for other peptide hormones, TNF causes the down-modulation of its own receptor. The process by which down-regulation occurs and the particular role of each of two recently identified receptors, however, are not understood. In this report w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a741fb70ecc786b2535ad36552ad4a2
https://doi.org/10.4049/jimmunol.152.7.3550
https://doi.org/10.4049/jimmunol.152.7.3550
Publikováno v:
The Journal of Immunology. 144:3789-3794
Monocyte products including TNF and IL-1 can stimulate hemopoietic growth factor production in vitro and in vivo. Endotoxin-resistant C3H/HeJ mice have a cellular defect in the regulation of TNF production and provide a model in which to examine the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f2cf6fe1db87ecfafe9b9d7ecd811da
https://doi.org/10.4049/jimmunol.144.10.3789
https://doi.org/10.4049/jimmunol.144.10.3789
Publikováno v:
Oncogene. 26(52)
Overexpression of epidermal growth factor (EGF) receptor and constitutive activation of nuclear factor-kappaB (NF-kappaB) are frequently encountered in tumor cells. Although EGF has been shown to induce NF-kappaB activation, the mechanism is poorly u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fc693b3c0a692088857a6dc1874deaab
https://pubmed.ncbi.nlm.nih.gov/26473948
https://pubmed.ncbi.nlm.nih.gov/26473948