Zobrazeno 1 - 10
of 54
pro vyhledávání: '"B. Aupetit-Faisant"'
Autor:
Kathleen M. Curnow, Yves Morel, J. Tourniaire, S. Portrat-Doyen, Leigh Pascoe, O. Richard, Paolo Mulatero, B. Aupetit-Faisant
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 83:4156-4161
Isolated deficiencies in aldosterone biosynthesis are caused by mutations in the CYP11B2 (aldosterone synthase) gene. Patients with this deficiency have impaired aldosterone synthesis, exhibit increased plasma renin activity, secrete increased amount
Autor:
Kathleen M. Curnow, Leigh Pascoe, Pierre Corvol, Xavier Jeunemaitre, Paolo Mulatero, B. Aupetit-Faisant, Celso E. Gomez-Sanchez, Franco Veglio, M. Foekling
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 83:3996-4001
CYP11B1 (11beta-hydroxylase) and CYP11B2 (aldosterone synthase) are 93% identical mitochondrial enzymes that both catalyze 11beta-hydroxylation of steroid hormones. CYP11B2 has the additional 18-hydroxylase and 18-oxidase activities required for conv
Autor:
B. Aupetit-Faisant
Publikováno v:
Journal of Clinical Endocrinology & Metabolism. 76:38-43
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 41:823-826
The authors incubated adrenal mitochondria to study the in vitro action of cortisol and testosterone on the transformation of corticosterone and 18-hydroxycorticosterone into aldosterone. The results show that cortisol at concentrations of 5 x 10(-6)
Autor:
J S, Silvestre, C, Heymes, A, Oubénaïssa, V, Robert, B, Aupetit-Faisant, A, Carayon, B, Swynghedauw, C, Delcayre
Publikováno v:
Archives des maladies du coeur et des vaisseaux. 92(8)
Synthesis of aldosterone (Aldo) and corticosterone (B) has been recently reported in rat heart. However, regulation of this synthesis in pathophysiological states remains unknown. Thus, this study aimed to analyze effects of a one-month myocardial in
Autor:
P, Mulatero, K M, Curnow, B, Aupetit-Faisant, M, Foekling, C, Gomez-Sanchez, F, Veglio, X, Jeunemaitre, P, Corvol, L, Pascoe
CYP11B1 (11beta-hydroxylase) and CYP11B2 (aldosterone synthase) are 93% identical mitochondrial enzymes that both catalyze 11beta-hydroxylation of steroid hormones. CYP11B2 has the additional 18-hydroxylase and 18-oxidase activities required for conv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::58f2a9bd098e9f424a61b7988d32ec7c
http://hdl.handle.net/2318/41859
http://hdl.handle.net/2318/41859
Autor:
B, Chamontin, N, Blanchouin-Emeric, J, Amar, F, Khatibi, I, Vernier, A, Bennet, B, Aupetit-Faisant, M, Salvador
Publikováno v:
Archives des maladies du coeur et des vaisseaux. 89(8)
The purpose of the study was to evaluate the interest of aldosterone precursors assays in arterial hypertension with hypokaliemia and adrenal nodules non due to aldosterone. Seven hypertensive patients, 3 men and 4 women, aged 59.5 +/- 10.1 years wer
Publikováno v:
Bulletin de l'Academie nationale de medecine. 179(7)
Fundamental research performed in the author's laboratory led to the understanding of mechanisms of the mineralocorticoid biosynthetic pathway. Sensitive assays were then developed to allow measurement of the different mineralocorticoid metabolites i
Autor:
X, Jeunemaitre, A, Charru, L, Pascoe, T T, Guyene, B, Aupetit-Faisant, C H, Shackleton, M, Schambelan, P F, Plouin, P, Corvol
Publikováno v:
Presse medicale (Paris, France : 1983). 24(27)
Dexamethasone-sensitive hyperaldosteronism is associated with early onset hypertension and primary hyperaldosteronism. Diagnosis is difficult but can be improved by genetic testing for the mutant gene.We collected the clinical, biological and genetic
Autor:
B Chamontin, J Amar, F Kuttenn, A Warnet, M Assayag, F Tenenbaum, B Aupetit-Faisant, Blanchouin-Emeric N, C Battaglia, A. Tabarin
Publikováno v:
The Journal of clinical endocrinology and metabolism. 80(9)
The aim of this study was to find out whether the dysfunction of aldosterone pathway, previously proposed as a marker of secretory adrenal carcinoma, is also found in nonsecretory adrenal carcinomas, which pose even more difficult diagnostic problems