Zobrazeno 1 - 10
of 208
pro vyhledávání: '"B. Arredondo"'
Autor:
Sebastian B. Arredondo, Daniel T. Reyes, Andrea Herrera-Soto, Muriel D. Mardones, Nibaldo C. Inestrosa, Lorena Varela-Nallar
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract In Alzheimer´s disease (AD) there is a reduction in hippocampal neurogenesis that has been associated to cognitive deficits. Previously we showed that Andrographolide (ANDRO), the main bioactive component of Andrographis paniculate, induces
Externí odkaz:
https://doaj.org/article/ca4b966c21c9405888f78dead9baf1c9
Autor:
Eva Ramos-Fernández, Macarena S. Arrázola, Carolina A. Oliva, Sebastián B. Arredondo, Lorena Varela-Nallar, Nibaldo C. Inestrosa
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-20 (2021)
Abstract Wnt signaling plays a key role in neurodevelopment and neuronal maturation. Specifically, Wnt5a stimulates postsynaptic assemblies, increases glutamatergic neurotransmission and, through calcium signaling, generates nitric oxide (NO). Trying
Externí odkaz:
https://doaj.org/article/390ac201791347b586eeab76239c7001
Autor:
Sofía Espinoza, Sebastián B. Arredondo, Francisca Barake, Francisco Carvajal, Fernanda G. Guerrero, Fabian Segovia-Miranda, David M. Valenzuela, Ursula Wyneken, Alejandro Rojas-Fernández, Waldo Cerpa, Loreto Massardo, Lorena Varela-Nallar, Alfonso González
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-17 (2020)
Abstract Background Cognitive dysfunction (CD) is common among patients with the autoimmune disease systemic lupus erythematosus (SLE). Anti-ribosomal P autoantibodies associate with this dysfunction and have neuropathogenic effects that are mediated
Externí odkaz:
https://doaj.org/article/706d6d1a38ce4746a112602d79945e18
Autor:
Miguel V. Guerra, Matías I. Cáceres, Andrea Herrera-Soto, Sebastián B. Arredondo, Manuel Varas-Godoy, Brigitte van Zundert, Lorena Varela-Nallar
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2022)
In the dentate gyrus of the adult hippocampus new neurons are generated from neural precursor cells through different stages including proliferation and differentiation of neural progenitor cells and maturation of newborn neurons. These stages are co
Externí odkaz:
https://doaj.org/article/62de9ae5e0b1424193784b28f2923b97
Autor:
Sebastian B. Arredondo, Daniela Valenzuela-Bezanilla, Muriel D. Mardones, Lorena Varela-Nallar
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Neurogenesis persists during adulthood in the dentate gyrus of the hippocampus. Signals provided by the local hippocampal microenvironment support neural stem cell proliferation, differentiation, and maturation of newborn neurons into functional dent
Externí odkaz:
https://doaj.org/article/64293ae60d764ac59effa6232ee3b4f3
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
Sebastian B Arredondo, Daniela Valenzuela-Bezanilla, Sebastian H Santibanez, Lorena Varela-Nallar
Publikováno v:
Stem Cells. 40:630-640
The subgranular zone (SGZ) of the hippocampal dentate gyrus (DG) is a neurogenic niche of the adult brain that contains neural stem cells (NSCs) able to generate excitatory glutamatergic granule neurons, which integrate into the DG circuit and contri
Autor:
Andrea Herrera-Soto, Sebastian B. Arredondo, Lorena Varela-Nallar, Muriel D. Mardones, Daniel T. Reyes, Nibaldo C. Inestrosa
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports
In Alzheimer´s disease (AD) there is a reduction in hippocampal neurogenesis that has been associated to cognitive deficits. Previously we showed that Andrographolide (ANDRO), the main bioactive component of Andrographis paniculate, induces prolifer