Zobrazeno 1 - 10
of 20
pro vyhledávání: '"B. Ahmed Abdi"'
Publikováno v:
Annals of the Rheumatic Diseases. 81:713.1-713
BackgroundSystemic sclerosis (SSc) is an immune-mediated connective tissue disease with clinical hallmark of inflammation, vasculopathy and fibrosis resulting in abnormal collagen and intercellular matrix formation in the dermis and internal organ. S
Publikováno v:
Annals of the Rheumatic Diseases. 80:702.2-703
Background:Systemic sclerosis (SSc) is a rare connective tissue disease with abnormalities in vasculopathy, immune dysregulation and fibrosis resulting in skin and internal organ damages. Severity of skin involvement is known to correlate with organ-
Akademický článek
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Akademický článek
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Publikováno v:
Poster Presentations.
Background The enzymes IDO degrades Trp into Kyn and is induced by IFN-gamma/IL-1. Neo is produced by monocytes/macrophages after IFN-gamma stimulation through the enzyme GTPCH and is a biomarker for monitoring immune activation in several diseases [
Autor:
B Ahmed Abdi, CH Ho, Gerry Coghlan, Voon H Ong, Benjamin E. Schreiber, Christopher P. Denton, Svetlana I. Nihtyanova
Publikováno v:
Poster Presentations.
Background Right heart catheterisation (RHC) is an important test for the diagnosis and subclassification of pulmonary hypertension (PH), one of the serious manifestations of systemic sclerosis (SSc). It provides haemodynamic information for diagnosi
Publikováno v:
Abstracts Accepted for Publication.
Background Macrophages and fibroblasts are key effector cell types present in scleroderma tissue 1 . While the effect of scleroderma fibroblast conditioned medium on macrophages has been previously studied 2 , less is known about the effect of sclero
Autor:
H S Rosário, Xu Shiwen, Christopher P. Denton, David Abraham, B Ahmed-Abdi, Richard Stratton, Sara Zafar, Zeinab Taki
Publikováno v:
Rheumatology.
Autor:
S. Nihtyanova, V. Ong, C. Black, C. Denton, P. Lutalo, W. Shattles, H. Jones, R. Nouri, A. Hepburn, M. Chard, N. Horwood, M. Lynn, O. Duke, P. Kiely, L. Zouita, U. Davies, R. Hughes, M. Lloyd, J. Nikitorowicz Buniak, X. Shiwen, D. Abraham, R. Stratton, T. Hugle, P. Schuetz, T. Daikeler, A. Tyndall, M. Matucci-Cerinic, U. A. Walker, J. M. van Laar, J. D. Pauling, V. Flower, N. McHugh, S. Liu, A. Leask, N. Aden, K. Khan, R. Hoyles, S. Bhagat, T. Drummond, C. Goh, R. Busch, F. Hall, P. Meyer, P. Moinzadeh, T. Krieg, M. Hellmich, J. Brinckmann, E. Neumann, U. Mueller-Ladner, A. Kreuter, D. Dumitresco, S. Rosenkranz, N. Hunzelmann, N. Binai, T. Huegle, J. van Laar, S. Sonnylal, A. Tam, J. Norman, B. de Crombrugghe, C. B. Chighizola, P. Luigi Meroni, G. Coghlan, F. Newton, E. C. Derrett-Smith, A. Dooley, R. Baliga, A. Hobbs, R. MacAllister, M. Futema, P. Pantelidis, E. Renzoni, B. E. Schreiber, G. J. Coghlan, A. U. Wells, K. Welsh, C. Fonseca, M. Ponticos, A. Wells, L. Guillevin, B. Schwierin, D. Rosenberg, M. Silkey, S. Parapuram, X. Shi-wen, B. Ahmed Abdi, S. Xu
Publikováno v:
Rheumatology. 50:iii129-iii137
Background: We have previously compared outcome in two groups of systemic sclerosis (SSc) patients with disease onset a decade apart and we reported data on 5 year survival and cumulative incidence of organ disease in a contemporary SSc cohort. The p
Autor:
Robert Lafyatis, B Ahmed-Abdi, Christopher P. Denton, Béla Suki, Joanna Nikitorowicz-Buniak, David Abraham, Matthew D. Layne, Xu Shiwen, Markella Ponticos, Ayuko Takahashi, Barbara D. Smith, Richard Stratton
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 5, p e0126015 (2015)
PLoS ONE, Vol 10, Iss 5, p e0126015 (2015)
In scleroderma (systemic sclerosis, SSc), persistent activation of myofibroblast leads to severe skin and organ fibrosis resistant to therapy. Increased mechanical stiffness in the involved fibrotic tissues is a hallmark clinical feature and a cause