Zobrazeno 1 - 2
of 2
pro vyhledávání: '"B. A. NACLERIO"'
Autor:
G.W. Antognoli, J.T. Shirley, A. Marfat, C.F. Wright, Thomas J. Carty, Frank W. Rusek, J. W. Watson, J. Delehunt, B. A. Naclerio, James F. Eggler, J.S. Pillar, Herbert Sherman, E.G. Andrews, Francis J. Sweeney, K. W. Freiert, R. Breslow, C. J. Mularski, V. L. Cohan, C J Pazoles, Lawrence S. Melvin, L.A. Rappach, John B. Cheng, David B. Damon, Jeanene E. Tickner, Judith L. Collins, P. Reiche, Hiroko Masamune, M. P. Carta, James D. Eskra, Hada William Andrew, R. J. Chambers
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 5:1365-1370
The development of two novel LTD 4 receptor antagonists as clinical candidates for the treatment of asthma is described. The first generation compound, CP-80,798, was found to be a balanced 5-lipoxygenase inhibitor (5-LOI)/LTD 4 antagonist (LTD 4 -A)
Autor:
E. G. ANDREWS, G. W. ANTOGNOLI, R. BRESLOW, M. P. CARTA, T. J. CARTY, R. J. CHAMBERS, J. B. CHENG, V. L. COHAN, J. L. COLLINS, D. B. DAMON, J. DELEHUNT, J. F. EGGLER, J. D. ESKRA, K. W. FREIERT, W. A. HADA, A. MARFAT, H. MASAMUNE, L. S. MELVIN, C. J. MULARSKI, B. A. NACLERIO, et al. et al.
Publikováno v:
ChemInform. 26