Zobrazeno 1 - 10
of 15
pro vyhledávání: '"B. A. Keyt"'
Autor:
M. K. Leabman, G. Hernandez, C. M. Ng, J. Tang, D. Pandya, K. C. Hart, K. Li, P. R. Hinton, J. So, I. Qazi, C. Y. Cheah, W. S. Kim, E. Budde, A. K. Gopal, T. Manley, C. H. Takimoto, A. M. Sinclair, S. F. Carroll, B. A. Keyt, M. F. Kotturi
Publikováno v:
HemaSphere, Vol 6, Pp 1161-1162 (2022)
Externí odkaz:
https://doaj.org/article/0b096a9e042e4b0d89131ab7c9e7b9c8
Publikováno v:
British Journal of Haematology. 111:517-523
Publikováno v:
Circulation. 92:3032-3040
Background The thrombolytic properties of a new variant of tissue plasminogen activator (TPA) (T103N, N117Q, KHRR 296-299 AAAA, or TNK-TPA) with longer plasma half-life, greater fibrin specificity, and increased resistance to inhibition by plasminoge
Publikováno v:
British journal of haematology. 111(2)
This study used two mutants of tissue-type plasminogen activator (t-PA) with resistance to inhibitors of fibrinolysis to define the contribution of plasminogen activator inhibitor (PAI)-1 and alpha2-antiplasmin (alpha2-AP) to the control of fibrin ly
Publikováno v:
The Journal of biological chemistry. 273(46)
Vascular endothelial growth factor (VEGF) has been found to have various functions on endothelial cells, the most prominent of which is the induction of proliferation and differentiation. In this report we demonstrate that VEGF or a mutant, selective
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 284(1)
Vascular endothelial growth factor (VEGF) produces beneficial angiogenesis in animal models of coronary and peripheral ischemia. However, intravenous bolus injection of Chinese hamster ovary cell (CHO)-derived VEGF produces adverse effects on hemodyn
Autor:
H W, Christinger, Y A, Muller, L T, Berleau, B A, Keyt, B C, Cunningham, N, Ferrara, A M, de Vos
Publikováno v:
Proteins. 26(3)
Vascular endothelial growth factor (VEGF) is a potent angiogenic factor with a unique specificity for vascular endothelial cells. In addition to its role in vasculogenesis and embryonic angiogenesis, VEGF is implicated in pathologic neovascularizatio
Autor:
G R, Thomas, H, Thibodeaux, C J, Errett, J M, Badillo, D T, Wu, C J, Refino, B A, Keyt, W F, Bennett
Publikováno v:
Thrombosis and haemostasis. 75(6)
Clinical experience suggests that thrombolytic-induced bleeding is associated with systemic activation of the thrombolytic system. Using fibrin specific variants of tissue-type plasminogen activator (t-PA) and making use of the apparent fibrin specif
Publikováno v:
The Journal of biological chemistry. 271(10)
Vascular endothelial growth factor (VEGF) expression in various cell types is induced by hypoxia and other stimuli. VEGF mediates endothelial cell proliferation, angiogenesis, vascular growth, and vascular permeability via the endothelial cell recept
Publikováno v:
Coronary artery disease. 6(9)
We have previously demonstrated that radiolabeled tissue-type plasminogen activation (tPA) in which the plasminogen-activating catalytic site has been inactivated binds avidly to thrombi and can be used for scintigraphic detection of pulmonary thromb