Experimental autoimmune encephalomyelitis in the common marmoset: a translationally relevant model for the cause and course of multiple sclerosis

Autor: B. A. 't Hart

Publikováno v: Primate Biology, Vol 6, Pp 17-58 (2019)

Aging Western societies are facing an increasing prevalence of chronic autoimmune-mediated inflammatory disorders (AIMIDs) for which treatments that are safe and effective are scarce. One of the main reasons for this situation is the lack of animal m

Externí odkaz: https://doaj.org/article/48ac2ee2b87e42eb9a6ffefd4c6893ca

Neurodegeneration meets immunology - A chemical biology perspective

Autor: C. Araman, B. A. ’t Hart

Publikováno v: Araman, C & ’t Hart, B A 2019, ' Neurodegeneration meets immunology – A chemical biology perspective ', Bioorganic and Medicinal Chemistry, vol. 27, no. 9, pp. 1911-1924 . https://doi.org/10.1016/j.bmc.2019.03.038

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33396d8e0f4496eeeedb2cb18e77e648
https://pubmed.ncbi.nlm.nih.gov/30910473

Inhibition of the development of collagen-induced arthritis in rhesus monkeys by a small molecular weight antagonist of CCR5

Autor: E. J. Remarque, Chuan-Chu Chou, B. A. ‘t Hart, Jayaram R. Tagat, Michel P.M. Vierboom, Julie M. Strizki, Catherine Pugliese-Sivo, Steensma Ruo, Paul J. Zavodny, Margreet Jonker, Satwant K. Narula, Stuart W. McCombie, Liesbeth Celebi-Paul

Publikováno v: Arthritis & Rheumatism. 52:627-636

Objective Collagen-induced arthritis (CIA) in the rhesus monkey is a nonhuman primate model of rheumatoid arthritis (RA). The close phylogenetic relationship between humans and the rhesus monkey makes this model useful for the preclinical safety and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6c4058f0b9e8df37959f63d244776a49
https://doi.org/10.1002/art.20850

Targeted delivery of CpG ODN to CD32 on human and monkey plasmacytoid dendritic cells augments IFNalpha secretion

Autor: B. A. ‘t Hart, Gerrit Koopman, Geert C. Mudde, Niels Beenhakker, I. Jolanda M. de Vries, Jurjen Tel

Publikováno v: Immunobiology, 217, 10, pp. 1017-24
Immunobiology, 217, 1017-24

Contains fulltext : 109682.pdf (Publisher’s version ) (Open Access) Atopic diseases are characterized by the presence of Th2 cells. Recent studies, in mice and man, demonstrated that allergen-specific Th2 responses can be shifted to Th0/Th1 respons

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fb98dff2e0286c782477afc694c5e0f
https://hdl.handle.net/2066/109682

Non-human primate models of multiple sclerosis

Autor: H P, Brok, J, Bauer, M, Jonker, E, Blezer, S, Amor, R E, Bontrop, J D, Laman, B A, 't Hart

Publikováno v: Immunological reviews. 183

The phylogenetic proximity between non-human primate species and humans is reflected by a high degree of immunological similarity. Non-human primates therefore provide important experimental models for disorders in the human population that are cause

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::283a807c3f2ef0aa383eee96cf3e6c24
https://pubmed.ncbi.nlm.nih.gov/11782256