Zobrazeno 1 - 10
of 102
pro vyhledávání: '"B. Arison"'
Autor:
B. Arison, Arlene Dahl-Roshak, Ping Lu, Zhiqiang An, Y. Q. Xia, Lucas Dennis, Jan S. Tkacz, A. Zhang
Publikováno v:
Molecular Genetics and Genomics. 273:207-216
A gene that encodes for a polyketide synthase (PKS) was cloned from the fungus Glarea lozoyensis and characterized. The gene (pks2) consists of four exons interrupted by three introns of 51, 59, and 65 bp, which are clustered at the 5' end. Its predi
Autor:
Avery Rosegay, Ralph Hirschmann, Wenqing Yao, L. Maechler, Paul A. Sprengeler, B. Arison, Amos B. Smith
Publikováno v:
Tetrahedron. 54:7179-7202
The discovery of somatostatin antagonists at one or more receptor subtypes remains an important goal. We therefore undertook the synthesis of the homodetic tricyclic peptide ( 1 ) hoping to cause conformational distortion and thereby achieve this bio
Autor:
B. Arison, R. Hirschmann, J. Salvino, W. C. Shakespeare, P. G. Spoors, A. B. Smith, Kyriacos C. Nicolaou, W. Vale, P. A. Sprengeler, Peter Hamley, M. R. Cascieri, M. A. Cichy, S. Pietranico, E. M. Leahy, C. D. Strader, R. M. Freidinger, C. Donaldson, T. Reisine, K. Raynor, L. Maechler
Publikováno v:
ChemInform. 25
Autor:
L. Maechler, Amos B. Smith, B. Arison, Paul A. Sprengeler, Ralph Hirschmann, Wenqing Yao, Avery Rosegay
Publikováno v:
ChemInform. 29
The discovery of somatostatin antagonists at one or more receptor subtypes remains an important goal. We therefore undertook the synthesis of the homodetic tricyclic peptide ( 1 ) hoping to cause conformational distortion and thereby achieve this bio
Autor:
S, Vickers, A D, Theoharides, B, Arison, S K, Balani, D, Cui, C A, Duncan, J D, Ellis, L M, Gorham, S L, Polsky, T, Prueksaritanont, H G, Ramjit, D E, Slaughter, K P, Vyas
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 27(11)
Tirofiban hydrochloride [L-tyrosine-N-(butylsulfonyl)-O-[4-(4-piperidinebutyl)] monohydrochloride, is a potent and specific fibrinogen receptor antagonist. Radiolabeled tirofiban was synthesized with either (3)H-label incorporated into the phenyl rin
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 26(8)
The metabolism of 3H/14C-labeled 4"-deoxy-4"-epimethylaminoavermectin B1a (MAB1a) benzoate, the major homologue (/=90%) of the avermectin insecticide emamectin benzoate, was studied in laying chickens. Ten Leghorn hens (Gallus domesticus) were orally
Autor:
S, Vickers, C A, Duncan, K P, Vyas, P H, Kari, B, Arison, S R, Prakash, H G, Ramjit, S M, Pitzenberger, G, Stokker, D E, Duggan
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 18(4)
Simvastatin (SV), an analog of lovastatin, is the lactone form of 1', 2', 6', 7', 8', 8a'-hexahydro-3,5-dihydroxy-2', 6'-dimethyl-8' (2", 2"-dimethyl-1"-oxobutoxy)-1'-naphthalene-heptanoic acid (SVA) which lowers plasma cholesterol by inhibiting 3-hy
Autor:
K P, Vyas, P H, Kari, S M, Pitzenberger, R A, Halpin, H G, Ramjit, B, Arison, J S, Murphy, W F, Hoffman, M S, Schwartz, E H, Ulm
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 18(2)
Structures of in vitro microsomal and in vivo metabolites of lovastatin, a new cholesterol-lowering drug, were elucidated with the combined application of HPLC, UV, fast atom bombardment-MS, and NMR spectroscopy. Liver microsomes from rats and mice c
Publikováno v:
Molecular Genetics & Genomics; Apr2005, Vol. 273 Issue 2, p207-216, 10p
Publikováno v:
Planta Medica. 56:623-623