Zobrazeno 1 - 10
of 47
pro vyhledávání: '"B-Lymphocytes/ immunology"'
Autor:
Thomas Korn, Francisco J. Quintana, Matteo Iannacone, Florent Ginhoux, Anne Dejean, Burkhard Becher, Selma Tuzlak, Ari Waisman
Publikováno v:
Nature Immunology
Nature Immunology, 2021, 22 (10), pp.1210-1217. ⟨10.1038/s41590-021-01009-w⟩
Nature Immunology, 2021, 22 (10), pp.1210-1217. ⟨10.1038/s41590-021-01009-w⟩
International audience; When helper T (TH) cell polarization was initially described three decades ago, the TH cell universe grew dramatically. New subsets were described based on their expression of few specific cytokines. Beyond TH1 and TH2 cells,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d1c5e3a4157d8f49697a041438addf5
https://ut3-toulouseinp.hal.science/hal-03694994
https://ut3-toulouseinp.hal.science/hal-03694994
Autor:
Seham Alameer, Tobias Schwerd, Giuseppe Indolfi, Joseph A. Church, Adelheid Cerwenka, Dominic Lenz, Ivo Barić, Jidnyasa Gujar, Thomas Giese, Johann Greil, Christian Staufner, Jens Pahl, Felix Distelmaier, Georg F. Hoffmann, Eberhard Lurz, Nikolas Boy, Anke Dick, Bianca Peters, Ellen Crushell, Holger Prokisch, Christoph Klein, Meena Balasubramanian, Stefan Kölker, Fabian Hauck, Daniele Serranti
Publikováno v:
J. Clin. Immunol., DOI: 10.1007/s10875-021-01110-7 (2021)
Journal of Clinical Immunology
Journal of Clinical Immunology
Purpose Biallelic pathogenic NBAS variants manifest as a multisystem disorder with heterogeneous clinical phenotypes such as recurrent acute liver failure, growth retardation, and susceptibility to infections. This study explores how NBAS-associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7176568d4fc4003562f22a1716e15672
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=62807
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=62807
Autor:
Elodie Belnoue, Floriane Auderset, Paul-Henri Lambert, Claire-Anne Siegrist, Beatris Mastelic-Gavillet
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
Frontiers in immunology, Vol. 11 (2020) P. 580974
Frontiers in Immunology
Frontiers in immunology, Vol. 11 (2020) P. 580974
Novel adjuvants, such as Toll-like receptors (TLRs) agonists, are needed for the development of new formulations able to circumvent limitations of current vaccines. Among TLRs, TLR7/8 agonists represent promising candidates, as they are well describe
Autor:
Joana Cardigos, Catarina Martins, Nuno Alves, Luís Miguel Borrego, Glória Nunes, Carlos F. G. C. Geraldes, José Vaz-Patto, Ana Luísa Papoila, Filipe Barcelos, Jaime Branco, Teresa Lopes
Publikováno v:
Rheumatology international. 38(6)
B-cells play a pivotal role in primary Sjögren's syndrome (pSS) pathogenesis. We aim to (1) evaluate the distribution of B-lymphocyte subpopulations in pSS and Sicca patients, (2) establish cut-off points that discriminate pSS from controls, (3) eva
Autor:
Steven K. H. Foung, Thomas F. Baumert
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology, Frontiers, 2018, 9, ⟨10.3389/fimmu.2018.02577⟩
Frontiers in Immunology, 2018, 9, pp.2577. ⟨10.3389/fimmu.2018.02577⟩
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology, Frontiers, 2018, 9, ⟨10.3389/fimmu.2018.02577⟩
Frontiers in Immunology, 2018, 9, pp.2577. ⟨10.3389/fimmu.2018.02577⟩
Publikováno v:
Nature Reviews Microbiology
Nature Reviews Microbiology, 2015, 13 (3), pp.173-184. ⟨10.1038/nrmicro3415⟩
Nature Reviews Microbiology, Nature Publishing Group, 2015, 13 (3), pp.173-184. ⟨10.1038/nrmicro3415⟩
Nature Reviews Microbiology, 13(3), 173-184. Nature Publishing Group
Nature Reviews Microbiology, 2015, 13 (3), pp.173-184. ⟨10.1038/nrmicro3415⟩
Nature Reviews Microbiology, Nature Publishing Group, 2015, 13 (3), pp.173-184. ⟨10.1038/nrmicro3415⟩
Nature Reviews Microbiology, 13(3), 173-184. Nature Publishing Group
International audience; B cells have long been regarded as simple antibody production units, but are now becoming known as key players in both adaptive and innate immune responses. However, several bacteria, viruses and parasites have evolved the abi
Autor:
Liza Ho, Frédéric Lajaunias, Carolin Dix, Eduardo Martinez-Soria, Lars Nitschke, Shozo Izui, Shuichi Kikuchi, Thomas Moll, R. Michael E. Parkhouse, Marie-Laure Santiago-Raber
Publikováno v:
International Immunology, Vol. 18, No 1 (2006) pp. 59-68
CD22 functions primarily as a negative regulator of B-cell receptor signaling. The Cd22a allele has been proposed as a candidate allele for murine systemic lupus erythematosus. In this study, we explored the possible expression of aberrant forms of C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89cf9c09265b624ad0fea203752ae567
http://doc.rero.ch/record/290776/files/dxh349.pdf
http://doc.rero.ch/record/290776/files/dxh349.pdf
Autor:
David A. Gross, Virginie Vasseur, Séverine Ciré, Muriel Sudres, Bernard Ryffel, Florence Boisgerault, Lea Brault, Véronique Blouin, Christine Le Bec, Sylvie Da Rocha, Anne Galy
Publikováno v:
Molecular Therapy
Molecular Therapy, Cell Press, 2012, 20 (8), pp.1571-81. ⟨10.1038/mt.2012.101⟩
Molecular Therapy, 2012, 20 (8), pp.1571-81. ⟨10.1038/mt.2012.101⟩
Molecular Therapy, Cell Press, 2012, 20 (8), pp.1571-81. ⟨10.1038/mt.2012.101⟩
Molecular Therapy, 2012, 20 (8), pp.1571-81. ⟨10.1038/mt.2012.101⟩
International audience; The administration of recombinant adeno-associated viral vectors (rAAV) for gene transfer induces strong humoral responses through mechanisms that remain incompletely characterized. To investigate the links between innate and
Autor:
Isabelle Angers, Stephen J. Galli, Adam Flaczyk, Salman T. Qureshi, Lothar Vogel, Ingo Spreitzer, Nicolas Gaudenzio, Sonja Wolfheimer, Stefan Schülke, B. Löschner, Mindy Tsai, Stephan Scheurer, Stefan Vieths
Publikováno v:
Allergy
Allergy, Wiley, 2015, 70 (10), pp.1259-1268. ⟨10.1111/all.12675⟩
Allergy, Wiley, 2015, 70 (10), pp.1259-1268. ⟨10.1111/all.12675⟩
Background Monophosphoryl lipid A (MPLA), a nontoxic TLR4 ligand derived from lipopolysaccharide (LPS), is used clinically as an adjuvant in cancer, hepatitis, and malaria vaccines and in allergen-specific immunotherapy. Nevertheless, its cell-activa
Autor:
Eric Espinosa, Nicolas Gaudenzio, Régis Joulia, Salvatore Valitutti, Jodie Lopez, Nicolas Blanchard, Magda Rodrigues
Publikováno v:
Nature Communications
Nature Communications, 2015, 6, pp.6174. ⟨10.1038/ncomms7174⟩
Nature Communications, 2015, 6, pp.6174. ⟨10.1038/ncomms7174⟩
International audience; Mast cells are tissue-resident immune cells that play a key role in inflammation and allergy. Here we show that interaction of mast cells with antibody-targeted cells induces the polarized exocytosis of their granules resultin