Výsledky vyhledávání - "B-Lymphocyte Subsets/immunology"

Boosting teenagers with acellular pertussis vaccines containing recombinant or chemically inactivated pertussis toxin: A randomized clinical trial

Autor: Saranath Lawpoolsri, Geraldine Blanchard Rohner, Barbara Lemaître, Hong Thai Pham, Indrajeet Kumar Poredi, Claire-Anne Siegrist, Olga Chatzis, Stéphane Grillet, Wassana Wijagkanalan, Pitchaya Boonrak, Elizabeth A. Clutterbuck, Simonetta Viviani, Carole Salomon, Marie Rohr, Jane Spiegel, Pailinrut Chinwangso

Publikováno v: Clinical Infectious Diseases, Vol. 68, No 7 (2019) pp. 1213-1222

Background Protection induced by acellular pertussis (aP) vaccines is partial and short-lived, especially in teenagers, calling for novel immunization strategies. Methods We conducted an investigator-driven proof-of-concept randomized controlled tria

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6ff967b17ce8982576a6fc4b4a07b5d
https://doi.org/10.1093/cid/ciy594

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Antigen Extraction and B Cell Activation Enable Identification of Rare Membrane Antigen Specific Human B Cells

Autor: Maria Zimmermann, Natalie Rose, John M. Lindner, Hyein Kim, Ana Rita Gonçalves, Ilaria Callegari, Mohammedyaseen Syedbasha, Lukas Kaufmann, Adrian Egli, Raija L. P. Lindberg, Ludwig Kappos, Elisabetta Traggiai, Nicholas S. R. Sanderson, Tobias Derfuss

Publikováno v: Frontiers in Immunology, Vol. 10 (2019) P. 829
Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)

Determining antigen specificity is vital for understanding B cell biology and for producing human monoclonal antibodies. We describe here a powerful method for identifying B cells that recognize membrane antigens expressed on cells. The technique dep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffe284d5fb6749a616a0f3ea49f57bab
https://doi.org/10.3389/fimmu.2019.00829

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B2-Lymphocyte responses to oxidative stress-derived antigens contribute to the evolution of nonalcoholic fatty liver disease (NAFLD)

Autor: Gabriele Giudici, Salvatore Sutti, E. Morello, Naresh Naik Ramavath, Michela Emma Burlone, Emanuele Albano, Pascal Schneider, S. Bruzzì, Alberto Toscani, Mario Pirisi, Maurizio Parola, Cristina Bozzola

Publikováno v: Free radical biology & medicine, vol. 124, pp. 249-259

Recent evidence implicates adaptive immunity as a key player in the mechanisms supporting hepatic inflammation during the progression of nonalcoholic fatty liver disease (NAFLD). In these settings, patients with NAFLD often show an increase in the ci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe2c9cf2a9e329d341bc4ad31316a779
https://pubmed.ncbi.nlm.nih.gov/29920340

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Memory B cell compartment constitution and susceptibility to recurrent lower respiratory tract infections in young children

Autor: Arnaud G L'Huillier, Stéphane Grillet, Cécile Delhumeau, Claire-Anne Siegrist, Klara M. Posfay-Barbe, Johan N. Siebert

Publikováno v: Journal of Leukocyte Biology, Vol. 93, No 6 (2013) pp. 951-62

A quantitative or qualitative defect in the memory B cell compartment is not identified in young children with recurrent lower respiratory tract infections. A proportion of children have recurrent LRTIs, mostly as a result of Spn, which persist after

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e25211af475ecaa35245b5f25167d8bb
https://doi.org/10.1189/jlb.0312117

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Comparison of a limiting dilution assay and ELISpot for detection of memory B-cells before and after immunisation with a protein-polysaccharide conjugate vaccine in children

Autor: Geraldine Blanchard-Rohner, Elizabeth A. Clutterbuck, Andrew J. Pollard, Grazia Galli

Publikováno v: Journal of Immunological Methods, Vol. 358, No 1-2 (2010) pp. 46-55

In the present study, the limiting dilution assay (LDA) and the ELISpot are compared in their ability to detect serogroup C meningococcal (MenC)-specific memory B-cells in peripheral blood of 12month old children, after 3-dose priming with serogroup

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ad4e2d3a57660fc39fcb4d156538e15
https://doi.org/10.1016/j.jim.2010.03.014

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CD81 gene defect in humans disrupts CD19 complex formation and leads to antibody deficiency

Autor: Liliane Schandené, Mirjam van der Burg, Françoise Janssen, Brigitte Adams, Menno C. van Zelm, Shoshana Levy, Alina Ferster, Chiung Chi Kuo, Françoise Mascart, Julie Smet, Jacques J.M. van Dongen

Publikováno v: The Journal of clinical investigation, 120 (4
Journal of Clinical Investigation, 120(4), 1265-1274. The American Society for Clinical Investigation

Antibody deficiencies constitute the largest group of symptomatic primary immunodeficiency diseases. In several patients, mutations in CD19 have been found to underlie disease, demonstrating the critical role for the protein encoded by this gene in a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52dda4d7d935bc9b091cd5d3e07346cb
https://pure.eur.nl/en/publications/1de5476c-1ed1-43f0-bdc2-cf1cc50df6d8

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In Vivo Induction of Type 1-Like Regulatory T Cells Using Genetically Modified B Cells Confers Long-Term IL-10-Dependent Antigen-Specific Unresponsiveness

Autor: Wim Janssens, Luc VanderElst, Thierry VandenDriessche, Vincent Carlier, Marinee Chuah, Marc Jacquemin, Jeroen Vanoirbeek, Roxana Roohi Ahangarani, Birgit Weynand, Jean-Marie Saint-Remy

Publikováno v: The Journal of Immunology. 183:8232-8243

Regulatory T cells (Tregs) hold much promise for the therapy of allergy and autoimmunity, but their use is hampered by lack of Ag specificity (natural Tregs) and difficulty to expand in vitro or in vivo (adaptive Tregs). We designed a method for in v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::772ae0e219f6c6858dd4c2d9a9a0dc97
https://doi.org/10.4049/jimmunol.0901777

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Raised immunoglobulin A and circulating T follicular helper cells are linked to the development of food allergy in paediatric liver transplant patients

Autor: A. Minne, Bruno Detry, R. De Bruyne, Frédéric Gottrand, S. Van Biervliet, Philippe Gevaert, Charles Pilette, M. Van Winckel, N. De Ruyck, Bart N. Lambrecht, Melissa Dullaers, Delfien Bogaert, Françoise Smets, S. Vande Velde, Etienne Sokal, Jérémy Vanhelst

Publikováno v: CLINICAL AND EXPERIMENTAL ALLERGY
Clinical and Experimental Allergy
Clinical and Experimental Allergy, Wiley, 2015, Clinical and experimental allergy, 45, pp.1060-1070. ⟨10.1111/cea.12514⟩
Clinical and Experimental Allergy, 45(6), 1060. Wiley-Blackwell
Clinical and Experimental Allergy, 2015, Clinical and experimental allergy, 45, pp.1060-1070. ⟨10.1111/cea.12514⟩
Clinical & Experimental Allergy, 45(6), 1060-1070. Wiley-Blackwell Publishing Ltd

BACKGROUND: Post transplant food allergy (LTFA) is increasingly observed after pediatric liver transplantation (LT). Although the immunopathology of LTFA remains unclear, immunoglobulin (Ig) E seems to be implicated. OBJECTIVE: To study humoral and c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23fe9131ee795a3686c12e76d504d76d
http://hdl.handle.net/20.500.12210/5172

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Differential Activation of Anti-Erythrocyte and Anti-DNA Autoreactive B Lymphocytes by the Yaa Mutation

Autor: Marie-Laure Santiago-Raber, Maria Pihlgren-Bosch, Thomas Moll, Dragan Marinkovic, Shozo Izui, Hirofumi Amano, Eduardo Martinez-Soria

Publikováno v: Journal of Immunology
Journal of Immunology, Vol. 174, No 2 (2005) pp. 702-709

An as-yet-unidentified mutation, Y-linked autoimmune acceleration (Yaa), is responsible for the accelerated development of lupus-like autoimmune syndrome in mice. In view of a possible role for Yaa as a positive regulator of BCR signaling, we have ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa8162c3f66bdbd4ea45d81fd63e7b71
https://doi.org/10.4049/jimmunol.174.2.702

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Differentially Regulated Expression and Function of CD22 in Activated B-1 and B-2 Lymphocytes

Autor: Shozo Izui, R. Michael E. Parkhouse, Thomas Moll, Yves Chicheportiche, Isabelle Semac, Lars Nitschke, Frédéric Lajaunias, Eduardo Martinez-Soria

Publikováno v: Journal of Immunology, Vol. 168, No 12 (2002) pp. 6078-6083
Scopus-Elsevier
CIÊNCIAVITAE

CD22 is a B cell-restricted transmembrane protein that apparently controls signal transduction thresholds initiated through the B cell Ag receptor (BCR) in response to Ag. However, it is still poorly understood how the expression of CD22 is regulated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a33ec62626860cdc3e0f48868372dc40
https://doi.org/10.4049/jimmunol.168.12.6078

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