Zobrazeno 1 - 10
of 54
pro vyhledávání: '"B-Cell Linker Protein"'
Akademický článek
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Autor:
Yang Zhou, Ermeng Xiong, Takeshi Tsubata, Masaki Hikida, Rongjian Hong, Ji-Yang Wang, Yanqing Wang, Yue Tang, Qing Min, Rika Ouchida, Nannan Lai, Jun Liu
Publikováno v:
European Journal of Immunology. 49:911-917
The BCR plays a central role in B cell development, survival, activation, and differentiation. We have identified the B cell novel protein 1 (BCNP1) as a new regulator of BCR signaling. BCNP1 contains a pleckstrin homology domain, three proline-rich
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13bfa916945ac27529234c57783f355d
https://doi.org/10.1002/eji.201847985
https://doi.org/10.1002/eji.201847985
Autor:
Qing Han, Rui Han, Ze-Quan Mo, Xue-Ming Dan, Hongyan Sun, Xiao-Chun Luo, Jiu-Le Wang, Yan-Wei Li
Publikováno v:
Fish & Shellfish Immunology. 81:399-407
B-cell linker protein (BLNK) is an adaptor protein that plays a crucial role in the B cell antigen receptor (BCR) signal pathway. To investigate the function of BLNK in teleost fish, we cloned a BLNK ortholog gene from the orange-spotted grouper (Epi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b37b3de3d5551b5d3deeba7400e198c
https://doi.org/10.1016/j.fsi.2018.07.046
https://doi.org/10.1016/j.fsi.2018.07.046
Autor:
Liangliang Mu, Xiaoxue Yin, Kailiang Han, Hairong Wu, Jianmin Ye, Zheng Guo, Liting Wu, Xia Bian
Publikováno v:
Aquaculture. 531:735986
B cell linker protein (BLNK), an adapter of SLP-76 family, plays an extremely important role in B cell receptor (BCR) signaling pathway that regulates proliferation, differentiation, and apoptosis of B cell. BLNK participates in the signal transducti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b68ec2164b51751ecd563538c50c770
https://doi.org/10.1016/j.aquaculture.2020.735986
https://doi.org/10.1016/j.aquaculture.2020.735986
Publikováno v:
Pathology - Research and Practice. 216:152821
This study aimed to investigate the clinicopathological and prognostic impact of B-cell linker (BLNK) protein expression in colorectal cancer (CRC) as its function in CRC remains unexplored. We performed immunohistochemical staining for BLNK using ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ecdcbbe24117f490ec59d4352a98ec1
https://doi.org/10.1016/j.prp.2020.152821
https://doi.org/10.1016/j.prp.2020.152821
Publikováno v:
Acta Biochimica et Biophysica Sinica. 46:526-530
The B-cell linker protein (BLNK) is an adaptor molecule and plays an important role in signal transduction of B-cell receptor (BCR) and pre-B-cell antigen receptor [1,2]. The BLNK contains a conserved C-terminal Src homology 2 (SH2) domain, a proline
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3971b2a2bf0796ffcf8db12bbecc539c
https://doi.org/10.1093/abbs/gmu027
https://doi.org/10.1093/abbs/gmu027
Publikováno v:
Scientific Reports
B cell linker protein (BLNK) is a central linker protein involved in B cell signal transduction in jawed vertebrates. In a previous study, we have reported the identification of a BLNK homolog named Lj-BLNK in lampreys. In this study, a 336 bp cDNA f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5f156fcd603996b518adf436ea9c484
Autor:
Darah Christie, Kathryn Hotke, Kristen M. Sokalski, Joseph Torchia, Rodney P. DeKoter, Jan Piskorz, Li S. Xu, Oren Zarnett, Gobi Thillainadesan
Publikováno v:
Paediatrics Publications
B cell acute lymphoblastic leukemia (B-ALL) is frequently associated with mutations or chromosomal translocations of genes encoding transcription factors. Conditional deletion of genes encoding the E26-transformation-specific transcription factors, P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3e8eac63045e3d64c3eb30db7050a41
https://doi.org/10.4049/jimmunol.1201267
https://doi.org/10.4049/jimmunol.1201267
Autor:
Li Li Chiu, Der-Yuan Chen, Chia Yu Yang, Joung-Liang Lan, Hongbo Hu, Hui Kai Kuo, Xiaohong Wang, Gregory A. Dement, Tse-Hua Tan, Ju Pi Li
Publikováno v:
Journal of Biological Chemistry. 287:11037-11048
Hematopoietic progenitor kinase 1 (HPK1) is a Ste20-like serine/threonine kinase that suppresses immune responses and autoimmunity. B cell receptor (BCR) signaling activates HPK1 by inducing BLNK/HPK1 interaction. Whether HPK1 can reciprocally regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::925efee03229016b24c156dd2883c6dc
https://doi.org/10.1074/jbc.m111.310946
https://doi.org/10.1074/jbc.m111.310946
Autor:
Manabu Futamura, Koki Kabu, Yasuyuki Nakamura, Hiroki Kamino, Hirofumi Arakawa, Noriaki Kitamura
Publikováno v:
Cancer Science. 99:2444-2454
Aneuploidy is a hallmark of human cancers. Although the maintenance of genomic integrity by p53 is important in preventing aneuploidy, its mechanism remains to be elucidated. Here we report evidence that B-cell linker protein (BLNK) mediates the inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95638c2c832a7286808ad9ddef94acde
https://doi.org/10.1111/j.1349-7006.2008.00990.x
https://doi.org/10.1111/j.1349-7006.2008.00990.x