Zobrazeno 1 - 10
of 694
pro vyhledávání: '"B cell responses"'
Autor:
Santosh Dhakal, Han-Sol Park, Kumba Seddu, John S. Lee, Patrick S. Creisher, Brittany Seibert, Kimberly M. Davis, Isabella R. Hernandez, Robert W. Maul, Sabra L. Klein
Publikováno v:
mBio, Vol 15, Iss 4 (2024)
ABSTRACTAdult females of reproductive age develop greater antibody responses to inactivated influenza vaccines (IIV) than males. How sex, age, and sex steroid concentrations impact B cells and durability of IIV-induced immunity and protection over 4
Externí odkaz:
https://doaj.org/article/9901ea5c319d48a3b41a8ad6886cf06d
Autor:
Jan M. Sobczak, Irena Barkovska, Ina Balke, Dominik A. Rothen, Mona O. Mohsen, Dace Skrastina, Anete Ogrina, Byron Martina, Juris Jansons, Janis Bogans, Monique Vogel, Martin F. Bachmann, Andris Zeltins
Publikováno v:
Vaccines, Vol 12, Iss 6, p 661 (2024)
T help (Th), stimulation of toll-like receptors (pathogen-associated molecular patterns, PAMPs), and antigen organization and repetitiveness (pathogen-associated structural patterns, PASPs) were shown numerous times to be important in driving B-cell
Externí odkaz:
https://doaj.org/article/dd21e3c1a8eb4f19965421a98dc62725
Autor:
Michael Piepenbrink, Fatai Oladunni, Aitor Nogales, Ahmed M. Khalil, Theresa Fitzgerald, Madhubanti Basu, Christopher Fucile, David J. Topham, Alexander F. Rosenberg, Luis Martinez-Sobrido, James J. Kobie
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT Due to antigenic drift and shift of influenza A viruses (IAV) and the tendency to elicit predominantly strain-specific antibodies, humanity remains susceptible to new strains of seasonal IAV and is at risk from viruses with pandemic potentia
Externí odkaz:
https://doaj.org/article/ebdd68412b794cc08dc6d57fed2668bf
Autor:
Dong Wei, Yingying Chen, Xiaoqi Yu, Yang-dian Lai, Wenxin Xu, Ping Ji, Zhitao Yang, Erzhen Chen, Xinxin Zhang, Ying Wang
Publikováno v:
Emerging Microbes and Infections, Vol 11, Iss 1, Pp 2474-2484 (2022)
BBIBP-CorV exerts efficient protection against SARS-CoV-2 infection. However, waning vaccine-induced humoral immune responses after two-dose vaccination have significantly undermined durable immuno-protection. In this study, we have demonstrated that
Externí odkaz:
https://doaj.org/article/a3bfd5f249b44a78a3da13b76772ceff
Autor:
Sharesta Khoenkhoen, Monika Ádori, Darío Solís-Sayago, Juliette Soulier, Jamie Russell, Bruce Beutler, Gabriel K. Pedersen, Gunilla B. Karlsson Hedestam
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Mice lacking the atypical inhibitory kappa B (IκB) protein, IκBNS, a regulator of the NF-κB pathway encoded by the nfkbid gene, display impaired antibody responses to both T cell-independent (TI) and T cell-dependent (TD) antigens. To better under
Externí odkaz:
https://doaj.org/article/36af7d3f9d0c45939da9ec1ad035fe3f
Autor:
Hildegund C. J. Ertl
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Gene transfer using adeno-associated viral (AAV) vectors has made tremendous progress in the last decade and has achieved cures of debilitating diseases such as hemophilia A and B. Nevertheless, progress is still being hampered by immune responses ag
Externí odkaz:
https://doaj.org/article/9c8dd2b53c9e4a8497f17b75a2c1b817
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
Taylor B. Engdahl, James E. Crowe
Publikováno v:
mSphere, Vol 5, Iss 4 (2020)
ABSTRACT Hantaviruses are zoonotic pathogens found in parts of Europe, Asia, South America, and North America, which can cause renal and respiratory failure with fatality rates up to 40%. There are currently no FDA-approved vaccines or therapeutics f
Externí odkaz:
https://doaj.org/article/f24b533fa7524db0a6a533a0318d4b8c