Zobrazeno 1 - 10
of 5 236
pro vyhledávání: '"B cell biology"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Autophagy is a regulated intracellular catabolic process by which invading pathogens, damaged organelles, aggregated proteins, and other macromolecules are degraded in lysosomes. It has been widely appreciated that autophagic activity plays an import
Externí odkaz:
https://doaj.org/article/48adb5ce92cf4133a3f45bd981efb4a6
Autor:
Jiajun Yap, Jimin Yuan, Wan Hwa Ng, Gao Bin Chen, Yuen Rong M. Sim, Kah Chun Goh, Joey Teo, Trixie Y. H. Lim, Shee Min Goay, Jia Hao Jackie Teo, Zhentang Lao, Paula Lam, Kanaga Sabapathy, Jiancheng Hu
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-17 (2023)
Abstract Hairy cell leukemia (HCL) is a B-lymphoma induced by BRAF(V600E) mutation. However, introducing BRAF(V600E) in B-lymphocytes fails to induce hematological malignancy, suggesting that BRAF(V600E) needs concurrent mutations to drive HCL ontoge
Externí odkaz:
https://doaj.org/article/3a07a7fcfb1b4d6f9d06508cc1d554f2
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/405bd5ff5a7148fdbec8d01a44c997f5
Autor:
Harry W. Schroeder
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/29544f6a1e6d4f88969d721525c12b9e
Autor:
Keith Conrad Fernandez, Laura Feeney, Ryan M Smolkin, Wei-Feng Yen, Allysia J Matthews, William Alread, John HJ Petrini, Jayanta Chaudhuri
Publikováno v:
eLife, Vol 11 (2022)
During the development of humoral immunity, activated B lymphocytes undergo vigorous proliferative, transcriptional, metabolic, and DNA remodeling activities; hence, their genomes are constantly exposed to an onslaught of genotoxic agents and process
Externí odkaz:
https://doaj.org/article/c5a7957245bf45f98cfc381bda670cc8
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Hypoxia is a common hallmark of healthy tissues in physiological states or chronically inflamed tissues in pathological states. Mammalian cells sense and adapt to hypoxia mainly through hypoxia-inducible factor (HIF) signaling. Many studies have show
Externí odkaz:
https://doaj.org/article/8cce3c9da0004e1da6d3ea0209edac34
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/c56f98ce10754b8a8905a2f4ecbbf5d8
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Both acute and chronic antibody-mediated allograft rejection (AMR), which are directly mediated by B cells, remain difficult to treat. Long-lived plasma cells (LLPCs) in bone marrow (BM) play a crucial role in the production of the antibodies that in
Externí odkaz:
https://doaj.org/article/c5fa4e1a34a54619aec0b2780aaa5909
Autor:
Su, Dan, Vanhee, Stijn, Soria, Rebeca, Gyllenbäck, Elin Jaensson, Starnes, Linda M., Højfeldt, Martina Kubec, Pedersen, Gabriel K., Yuan, Joan, Daniel, Jeremy A.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2017 Oct . 114(44), E9328-E9337.
Externí odkaz:
https://www.jstor.org/stable/26488887
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