Zobrazeno 1 - 10
of 2 456
pro vyhledávání: '"B cell Development"'
Publikováno v:
Immunity & Ageing, Vol 21, Iss 1, Pp 1-18 (2024)
Abstract B-1 cells have intricate biology, with distinct function, phenotype and developmental origin from conventional B cells. They generate a B cell receptor with conserved germline characteristics and biased V(D)J recombination, allowing this inn
Externí odkaz:
https://doaj.org/article/f166d4bd8be746d8b5f511186de1f3b5
Autor:
Rens Peeters, Julia Jellusova
Publikováno v:
Molecular Oncology, Vol 18, Iss 7, Pp 1795-1813 (2024)
In recent years, the field of immunometabolism has solidified its position as a prominent area of investigation within the realm of immunological research. An expanding body of scientific literature has unveiled the intricate interplay between energy
Externí odkaz:
https://doaj.org/article/8ef861e4f0f94ec3b6b47a7d1a970824
Autor:
Jia‐Chen Liu, Ke Zhang, Xu Zhang, Fei Guan, Hu Zeng, Masato Kubo, Pamela Lee, Fabio Candotti, Louisa Katherine James, Niels Olsen Saraiva Camara, Kamel Benlagha, Jia‐Hui Lei, Huamei Forsman, Lu Yang, Wei Xiao, Zheng Liu, Chao‐Hong Liu
Publikováno v:
MedComm, Vol 5, Iss 8, Pp n/a-n/a (2024)
Abstract Maturation of the secondary antibody repertoire requires class‐switch recombination (CSR), which switches IgM to other immunoglobulins (Igs), and somatic hypermutation, which promotes the production of high‐affinity antibodies. Following
Externí odkaz:
https://doaj.org/article/b12782f9506642e8a5b259d22218e319
Publikováno v:
Biomedical Journal, Vol 47, Iss 2, Pp 100628- (2024)
Background: DnaJ homolog subfamily A member 3 (DNAJA3), also known as the tumorous imaginal disc (Tid1), is shown to be crucial in T cell development. DNAJA3 functions as a tumor suppressor implicated in lymphocyte development and survival. However,
Externí odkaz:
https://doaj.org/article/5d4e02f893f04093b3559f6246917259
Publikováno v:
Poultry Science, Vol 103, Iss 2, Pp 103294- (2024)
ABSTRACT: The bursa of Fabricius (BF) is pivotal for B lymphocyte ontogenesis. In the present investigation, a novel bursal peptide, designated BP7, was extracted from BF and was found to stimulate colony-forming unit pre-B (CFU pre-B) formation at v
Externí odkaz:
https://doaj.org/article/f297b0fa909a4c2ab97d11942301a94b
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
During lymphocyte development, a diverse repertoire of lymphocyte antigen receptors is produced to battle against pathogens, which is the basis of adaptive immunity. The diversity of the lymphocyte antigen receptors arises primarily from recombinatio
Externí odkaz:
https://doaj.org/article/13665ff9bc6f4d4f8cc3635209c759e5
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
NF-κB signaling is essential to an effective innate and adaptive immune response. Many immune-specific functional and developmental outcomes depend in large on NF-κB. The formidable task of sorting out the mechanisms behind the regulation and outco
Externí odkaz:
https://doaj.org/article/4b40539551e14940ab9c787ee51d00a1
Autor:
Jaya Prakash Chalise, Ali Ehsani, Mengistu Lemecha, Yu-Wen Hung, Guoxiang Zhang, Garrett P. Larson, Keiichi Itakura
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
During B cell development in bone marrow, large precursor B cells (large Pre-B cells) proliferate rapidly, exit the cell cycle, and differentiate into non-proliferative (quiescent) small Pre-B cells. Dysregulation of this process may result in the fa
Externí odkaz:
https://doaj.org/article/74b33e895d8741968fbb75b5886ae35b
Publikováno v:
Biochemistry and Biophysics Reports, Vol 34, Iss , Pp 101451- (2023)
B cell activating factor (BAFF) plays an important role in antibody production through differentiation and maturation of B cells mainly in secondary lymphoid organs. On the other hand, the role of BAFF in the bone marrow, the primary lymphoid organ o
Externí odkaz:
https://doaj.org/article/5cf5c676e48f4bb99b46bc99af9d74a4
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