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Publikováno v:
Journal of glaucoma. 2(2)
We evaluated the effects of three specific glycosaminoglycan-degrading enzymes, chondroitinase ABC, testicular hyaluronidase, and heparinase, on the intraocular pressure (IOP) and the anterior chamber structures of bovine eyes. The anterior segment o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::67fbb6333aa959579e7fe480c3b2a728
https://pubmed.ncbi.nlm.nih.gov/19920491
https://pubmed.ncbi.nlm.nih.gov/19920491
Publikováno v:
Molecular medicine (Cambridge, Mass.). 7(7)
BACKGROUND: Keratoconus is a noninflammatory disease characterized by thinning and scarring of the central portion of the cornea. The etiology is unclear. In this study, we sought to identify mRNAs that are differentially expressed in the stroma of k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7af657e3d8996ea4ac7f6f60e234a7c9
https://pubmed.ncbi.nlm.nih.gov/11683372
https://pubmed.ncbi.nlm.nih.gov/11683372
Publikováno v:
Investigative ophthalmologyvisual science. 42(9)
Keratoconus is a progressive disease that thins and scars the corneal stroma. In keratoconus corneas, levels of degradative enzymes, including lysosomal acid phosphatase (LAP) and cathepsin B, are elevated, and those of the inhibitors alpha1-proteina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9511d123cfa0c36979aa10a25d13ffbc
https://pubmed.ncbi.nlm.nih.gov/11481261
https://pubmed.ncbi.nlm.nih.gov/11481261
Publikováno v:
Investigative ophthalmologyvisual science. 42(1)
To elucidate the roles of Rho-associated protein kinase (ROCK) in regulating intraocular pressure (IOP) and outflow facility in the rabbit eye.A specific ROCK inhibitor Y-27632 was used. The IOP, the outflow facility, and the pupil diameter were dete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3dd26240f616d30063c1e428dac8f241
https://pubmed.ncbi.nlm.nih.gov/11133858
https://pubmed.ncbi.nlm.nih.gov/11133858
Publikováno v:
Investigative ophthalmologyvisual science. 39(7)
Keratoconus is characterized by thinning and scarring of the central region of the cornea. Previous research showed that, in corneas obtained from patients with keratoconus, lysosomal enzyme activities are elevated, whereas levels of protease inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4f451007c43bbe864b118c23f07e2465
https://pubmed.ncbi.nlm.nih.gov/9620070
https://pubmed.ncbi.nlm.nih.gov/9620070
Publikováno v:
Investigative ophthalmologyvisual science. 38(2)
Keratoconus is characterized by thinning and scarring of the central region of the cornea. The authors have shown, in corneas obtained from patients with keratoconus, that lysosomal enzyme activities are elevated, whereas levels of protease inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a9dbeb885f2c707048887beed5cb59cb
https://pubmed.ncbi.nlm.nih.gov/9040486
https://pubmed.ncbi.nlm.nih.gov/9040486
Publikováno v:
Investigative ophthalmologyvisual science. 37(1)
To examine the adhesion of human trabecular meshwork cells with various extracellular matrix (ECM) proteins and to evaluate the roles and distribution of integrin receptors.Cultured human trabecular meshwork cells were added to 96-well plates either
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::30035b2b4b854bcb6e260785674eb727
https://pubmed.ncbi.nlm.nih.gov/8550313
https://pubmed.ncbi.nlm.nih.gov/8550313
Publikováno v:
Investigative ophthalmologyvisual science. 36(5)
To investigate the response of trabecular meshwork cells to phagocytic events.Cultured bovine trabecular meshwork cells were established and exposed to latex microspheres for 40 to 44 hours. After phagocytosis, the cohesiveness of cells to their unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c3628648ed5b10cc0cf1449978c6f7c9
https://pubmed.ncbi.nlm.nih.gov/7706026
https://pubmed.ncbi.nlm.nih.gov/7706026
Publikováno v:
Investigative ophthalmologyvisual science. 35(12)
To compare the levels of alpha 2-macroglobulin, one of the major proteinase inhibitors, in corneas with keratoconus to those in normal human corneas and corneas with other diseases.An immunoperoxidase technique was used to visualize the presence of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a0292d444f511f44860c865b96946f7f
https://pubmed.ncbi.nlm.nih.gov/7525507
https://pubmed.ncbi.nlm.nih.gov/7525507