Výsledky vyhledávání

Detection of hog cholera virus and differentiation from other pestiviruses by polymerase chain reaction

Autor: B Wirz, D B Mitchell, J D Tratschin, H K Müller

Publikováno v: Journal of Clinical Microbiology. 31:1148-1154

Reverse transcription coupled with the polymerase chain reaction (RT-PCR) was used for the detection and differentiation of pestiviruses. For this purpose, one primer pair was selected from a highly conserved region of the genome of pestiviruses. Usi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d003f262787d2825f2511a00752066b
https://doi.org/10.1128/jcm.31.5.1148-1154.1993

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A generic log-service supporting fast recovery in distributed fault-tolerant systems

Autor: E. Nett, B. Wirz

Publikováno v: Proceedings 1993 IEEE Workshop on Advances in Parallel and Distributed Systems.

Logs are an important facility for fault-tolerant distributed systems since they allow to reliably store information that is needed to provide a global consistent system state also in the presence of failures. The authors focus on the problem of fast

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e90ab5fe813cc91b9e8a47a0beeb19a1
https://doi.org/10.1109/apads.1993.588858

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4,5-bis(4-fluoroanilino)phthalimide: A selective inhibitor of the epidermal growth factor receptor signal transduction pathway with potent in vivo antitumor activity

Autor: E, Buchdunger, H, Mett, U, Trinks, U, Regenass, M, Müller, T, Meyer, P, Beilstein, B, Wirz, P, Schneider, P, Traxler

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 1(8)

Deregulated signal transduction via the epidermal growth factor (EGF) receptor family of tyrosine protein kinase growth factor receptors is associated with proliferative diseases such as cancer and psoriasis. In an attempt to selectively block signal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f9f8edbee9857254cd5db359729ad966
https://pubmed.ncbi.nlm.nih.gov/9816050

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Measurement of clomipramine, N-desmethyl-clomipramine, imipramine, and dehydroimipramine in biological fluids by selective ion monitoring, and pharmacokinetics of clomipramine

Autor: J P Dubois, W Küng, B Wirz, W Theobald

Publikováno v: Clinical Chemistry. 22:892-897

To quantitatively determine tricyclic antidepressant agents, we used a combined gas chromatograph/mass spectrometer system, and deuterium-labeled internal standards. Recovery exceeds 95% and the coefficient of variation is less than 4% for human whol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::93b6d743629de61d3960ff21bdcaaeac
https://doi.org/10.1093/clinchem/22.6.892

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Reaction of 14CO2 with grignard reagents to form either carboxylic acids or ketones. A novel convenient route to [2-14C] glycerol and [1-14C] Glycolic acid

Autor: W. Küng, B. Wirz

Publikováno v: Journal of Labelled Compounds and Radiopharmaceuticals. 20:635-653

The reaction of CO2 with GRIGNARD reagents carrying an ether grouping in a sterically suitable position can be directed to afford predominantly either the carboxylic acid or the symmetrical ketone. Thus, the magnesiumorganic compounds prepared from c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9a28ca747e04728a1c6f5e47b80cf029
https://doi.org/10.1002/jlcr.2580200510

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Synthesis of carbon-14- and tritium-labelled 4-amino-3- (4-chlorophenyl) -butyric acid (baclofen)

Autor: J. W. Faigle, W. Küng, B. Wirz, E. Kocher

Publikováno v: Journal of Labelled Compounds and Radiopharmaceuticals. 20:213-231

Two preparations of carbon-14 labelled 4-amino-3-(4-chlorophenyl)-butyric acid are described : First, the label is introduced in the 3-position of the butyric acid chain in nine steps, starting from 14CO2. The total radiochemical yield is 30%, calcul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2fd977fd7fe87e15e36d42cca07ab323
https://doi.org/10.1002/jlcr.2580200209

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Synthesis of 14C- and 3H-labelled 4-(4-nitrophenyl)aminophenylisothiocyanate (GO 9333 / CGP 4540; amoscanate

Autor: B. Anjaneyulu, B. Wirz, Kuppuswamy Nagarajan, W. Kueng, R. K. Maller

Publikováno v: Journal of Labelled Compounds and Radiopharmaceuticals. 22:313-327

Amoscanate labelled with carbon-14 on the isothiocyanate carbon atom was prepared in an overall yield of 13% at a specific activity of 4.13 μCi/mg from potassium [14C]thiocyanate. The 4-nitro[U-14C]phenyl ring labelled compound was synthesized in 20

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::791b952fe9766cea75c8faacb678ae16
https://doi.org/10.1002/jlcr.2580220403

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