Zobrazeno 1 - 10
of 3 833
pro vyhledávání: '"B West"'
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
IntroductionMany American employers seek to alleviate employee mental health symptoms through resources like employee assistance programs (EAPs), yet these programs are often underutilized. This pilot study explores the design of a behavioral science
Externí odkaz:
https://doaj.org/article/1d07753ef32748c5889914d21d89af2a
Autor:
Vedad Delic, Joshua H. Karp, Maynard Guzman, Gabriel R. Arismendi, Katherine J. Stalnaker, Julia A. Burton, Kathleen E. Murray, Joshua P. Stamos, Kevin D. Beck, Arpine Sokratian, Andrew B. West, Bruce A. Citron
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-16 (2022)
Abstract Population studies have shown that traumatic brain injury (TBI) is associated with an increased risk for Parkinson’s disease (PD) and among U.S. Veterans with a history of TBI this risk is 56% higher. The most common type of TBI is mild (m
Externí odkaz:
https://doaj.org/article/d8fbf686468f4774a37e2ef903cce55a
Autor:
Linda J. vanWeele, Sabra I. Djomehri, Shang Cai, Jane Antony, Shaheen S. Sikandar, Dalong Qian, William H. D. Ho, Robert B. West, Ferenc A. Scheeren, Michael F. Clarke
Publikováno v:
Molecular Oncology, Vol 16, Iss 17, Pp 3128-3145 (2022)
As precision medicine increases the response rate of treatment, tumors frequently bypass inhibition, and reoccur. In order for treatment to be effective long term, the mechanisms enabling treatment adaptation need to be understood. Here, we report a
Externí odkaz:
https://doaj.org/article/8d6bdff9fa234733908de5b2990ded0f
Autor:
Enquan Xu, Ravindra Boddu, Hisham A. Abdelmotilib, Arpine Sokratian, Kaela Kelly, Zhiyong Liu, Nicole Bryant, Sidhanth Chandra, Samantha M. Carlisle, Elliot J. Lefkowitz, Ashley S. Harms, Etty N. Benveniste, Talene A. Yacoubian, Laura A. Volpicelli-Daley, David G. Standaert, Andrew B. West
Publikováno v:
Molecular Neurodegeneration, Vol 17, Iss 1, Pp 1-19 (2022)
Abstract Background Leucine rich repeat kinase 2 (LRRK2) and SNCA are genetically linked to late-onset Parkinson’s disease (PD). Aggregated α-synuclein pathologically defines PD. Recent studies identified elevated LRRK2 expression in pro-inflammat
Externí odkaz:
https://doaj.org/article/650263aba80f4a2ebcfa23775edbadc2
Autor:
Charlotte F. Brzozowski, Baraa A. Hijaz, Vijay Singh, Nolwazi Z. Gcwensa, Kaela Kelly, Edward S. Boyden, Andrew B. West, Deblina Sarkar, Laura A. Volpicelli-Daley
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-18 (2021)
Abstract Pathologic inclusions composed of α-synuclein called Lewy pathology are hallmarks of Parkinson’s Disease (PD). Dominant inherited mutations in leucine rich repeat kinase 2 (LRRK2) are the most common genetic cause of PD. Lewy pathology is
Externí odkaz:
https://doaj.org/article/529d6d304c07412f8ead36c5d416d3e5
Autor:
Darci Phillips, Magdalena Matusiak, Belén Rivero Gutierrez, Salil S. Bhate, Graham L. Barlow, Sizun Jiang, Janos Demeter, Kimberly S. Smythe, Robert H. Pierce, Steven P. Fling, Nirasha Ramchurren, Martin A. Cheever, Yury Goltsev, Robert B. West, Michael S. Khodadoust, Youn H. Kim, Christian M. Schürch, Garry P. Nolan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
PD-1 blockade is effective for only a subset of patients with cutaneous T cell lymphomas. Here, the authors report a spatial biomarker that uses immune and cancer cell topography to predict response to PD-1 blockade in this disease.
Externí odkaz:
https://doaj.org/article/185b95b3ae0241efb2f75ef0ed8fba8c
Publikováno v:
Ecology and Evolution, Vol 11, Iss 17, Pp 11808-11825 (2021)
Abstract In seasonally dry tropical forests, plant functional type can be classified as deciduous low wood density, deciduous high wood density, or evergreen high wood density species. While deciduousness is often associated with drought‐avoidance
Externí odkaz:
https://doaj.org/article/30206e61c3d748b0be0cf0fa5ef7d474
Publikováno v:
JMIR Formative Research, Vol 6, Iss 11, p e42343 (2022)
BackgroundPreventive screenings such as mammograms promote health and detect disease. However, mammogram attendance lags clinical guidelines, with roughly one-quarter of women not completing their recommended mammograms. A scalable digital health int
Externí odkaz:
https://doaj.org/article/f9dd4df1e65c4993b70529b8f8e7b58b
Autor:
James J. Yu, Amy L. Non, Erica C. Heinrich, Wanjun Gu, Joe Alcock, Esteban A. Moya, Elijah S. Lawrence, Michael S. Tift, Katie A. O'Brien, Jay F. Storz, Anthony V. Signore, Jane I. Khudyakov, William K. Milsom, Sean M. Wilson, Cynthia M. Beall, Francisco C. Villafuerte, Tsering Stobdan, Colleen G. Julian, Lorna G. Moore, Mark M. Fuster, Jennifer A. Stokes, Richard Milner, John B. West, Jiao Zhang, John Y. Shyy, Ainash Childebayeva, José Pablo Vázquez-Medina, Luu V. Pham, Omar A. Mesarwi, James E. Hall, Zachary A. Cheviron, Jeremy Sieker, Arlin B. Blood, Jason X. Yuan, Graham R. Scott, Brinda K. Rana, Paul J. Ponganis, Atul Malhotra, Frank L. Powell, Tatum S. Simonson
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The ability to respond rapidly to changes in oxygen tension is critical for many forms of life. Challenges to oxygen homeostasis, specifically in the contexts of evolutionary biology and biomedicine, provide important insights into mechanisms of hypo
Externí odkaz:
https://doaj.org/article/ad6281793d794d10a1e325e2249296a9
Autor:
Rachel E. Adams, Jason B. West
Publikováno v:
Frontiers in Water, Vol 4 (2022)
Across the karst landscape of Quintana Roo, Mexico, plant access to nutrients and water appears limited by generally shallow soil. However, underlying this surface are heterogenous pockets in bedrock and deeper, stable groundwater, suggesting the pot
Externí odkaz:
https://doaj.org/article/cec598b12ad0448fac3cb43dd7802b88