Zobrazeno 1 - 10
of 25
pro vyhledávání: '"B W O'Neil"'
Autor:
J. M. Gaukroger, G Knowles, Maria Saveria Campo, B. W. O'Neil, G.J. Grindlay, L. M. Chandrachud
Publikováno v:
Journal of General Virology. 77:1577-1583
Prophylactic vaccination of cattle with the N terminus (L2a, aa 11–200) of the minor capsid protein L2 completely prevented bovine papillomavirus type 4 (BPV-4) infection of the alimentary canal. To investigate the mechanisms underlying protection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b1d948c6375ce921461cae246a97032
https://doi.org/10.1099/0022-1317-77-7-1577
https://doi.org/10.1099/0022-1317-77-7-1577
Autor:
A. Armstrong, Reinhard Kirnbauer, John T. Schiller, E. R. Wagner, Maria Saveria Campo, G.J. Grindlay, Gail M. McGarvie, B. W. O'Neil, L. M. Chandrachud, D R Lowy
Publikováno v:
Virology. 219:37-44
Virus-like particles were produced in insect cells containing either the L1 and L2 capsid proteins of bovine papillomavirus type 4 (BPV-4) or only the L1 protein. Both preparations of VLPs proved to be extremely effective prophylactic vaccines. Thirt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8496cdf897ef57cc6282e0a9be4b7948
https://doi.org/10.1006/viro.1996.0220
https://doi.org/10.1006/viro.1996.0220
Publikováno v:
Carcinogenesis. 15:1597-1601
Bovine papillomavirus type 4 (BPV-4) is the aetiological agent of epithelial papillomas of the upper alimentary canal in cattle. These benign tumours can become a focus for transformation to squamous cell carcinomas in animals feeding on bracken fern
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::639d317bd7d2f46aa9f83048d79838c6
https://doi.org/10.1093/carcin/15.8.1597
https://doi.org/10.1093/carcin/15.8.1597
Publikováno v:
Journal of comparative pathology. 129(2-3)
Extensive papillomatosis was identified in a heifer born and raised in Scotland and a steer born and raised in England. In both cases, the papillomas extended from the mouth and tongue to the reticulum. Although cases of florid papillomatosis of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::703cd49652398876e59fd9a835dd6d35
https://pubmed.ncbi.nlm.nih.gov/12921714
https://pubmed.ncbi.nlm.nih.gov/12921714
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 96(2)
Modeling of disease pathogenesis and immunity often is carried out in large animals that are natural targets for pathogens of human or economic relevance. Although murine mAbs are a valuable tool in identifying certain host/pathogen interactions, pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78bee92e102ba87abf28b4032c141da1
https://pubmed.ncbi.nlm.nih.gov/9892686
https://pubmed.ncbi.nlm.nih.gov/9892686
Autor:
Graham Knowles, G.Joan Grindlay, M. Saveria Campo, Fiona Curtis, L. M. Chandrachud, B. W. O'Neil
Publikováno v:
Virology. 234(2)
The first 200 N-terminus amino acids of the L2 capsid protein of BPV-4 (designated L2a) are an effective prophylactic vaccine against BPV-4 infection. Vaccination with L2a induces the production of virus neutralizing antibodies, and when L2a antibodi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33e94d32d019047934861bf145f04d35
https://pubmed.ncbi.nlm.nih.gov/9268157
https://pubmed.ncbi.nlm.nih.gov/9268157
Publikováno v:
Veterinary journal (London, England : 1997). 154(1)
In cattle infection of the upper alimentary canal mucosa by bovine papillomavirus type 4 (BPV-4) results in the development of papillomas which can progress to cancer in animals fed on bracken fern. This paper describes a study of the cellular and su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19e565e31732c5e85773d12ecaa01825
https://pubmed.ncbi.nlm.nih.gov/9265855
https://pubmed.ncbi.nlm.nih.gov/9265855
Publikováno v:
Research in veterinary science. 62(3)
The minor capsid protein L2 of bovine papillomavirus type 4 (BPV-4) is a very effective prophylactic vaccine which induces the production of virus neutralising antibodies and prevents virus-induced papillomatosis. The virus neutralising activity resi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::180b6f81592a8bb48f6eb247b71b805c
https://pubmed.ncbi.nlm.nih.gov/9300551
https://pubmed.ncbi.nlm.nih.gov/9300551
Papillomavirus-induced lesions often regress spontaneously in both humans and animals. Papilloma regression is deemed to be due to a cell-mediated immune response, the nature of which is still ill defined, and is accompanied by immune cell infiltrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64f322502c66c8745e9184c9be974dd8
https://europepmc.org/articles/PMC190935/
https://europepmc.org/articles/PMC190935/
Autor:
L. M. Chandrachud, William F.H. Jarrett, Eric R. Wagner, Gail M. McGarvie, M. Saveria Campo, G.Joan Grindlay, B. W. O'Neil
Publikováno v:
Virology. 211(1)
We have previously shown that cattle vaccinated with L2, the minor structural protein of bovine papillomavirus-4 (BPV-4), do not develop alimentary papillomas upon challenge with BPV-4. Analysis of the B and T cell response in L2-vaccinated animals s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c761ff9b6217092bf468e3f81038cc9c
https://pubmed.ncbi.nlm.nih.gov/7544045
https://pubmed.ncbi.nlm.nih.gov/7544045