Zobrazeno 1 - 10
of 18
pro vyhledávání: '"B W Pogue"'
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Imaging Cherenkov emission during radiotherapy can provide information on the delivered radiation dose, but is attenuated by optical properties of the tissue. Here the authors derive a correction factor applicable to breast X-ray radiotherapy in huma
Externí odkaz:
https://doaj.org/article/6436cb03709d4353872a69d6c1c2b2ab
Publikováno v:
The Journal of Physical Chemistry B. 127:2289-2301
Autor:
B. W. Pogue, M. S. Patterson
Publikováno v:
Advances in Optical Imaging and Photon Migration.
A multigrid finite difference method for solving the diffusion is used to solve the forward optical imaging problem. Simulations of near-infrared imaging are presented for some simple test objects, using typical soft tissue interaction coefficients.
Autor:
Tayyaba Hasan, Rowland Illing, B. W. Pogue, M. T. Huggett, Marco Novelli, A. Gillams, SP Pereira, S. Mosse, Michael Jermyn, E. Kent, Sg Bown
Publikováno v:
British Journal of Cancer
Background: Patients with pancreatic cancer have a poor prognosis apart from the few suitable for surgery. Photodynamic therapy (PDT) produces localised tissue necrosis but previous studies using the photosensitiser meso-tetrahydroxyphenylchlorin (mT
Autor:
Tayyaba Hasan, B. W. Pogue, E. Kent, S. Mosse, SP Pereira, Sg Bown, A. Gillams, Michael Jermyn, M. T. Huggett
Publikováno v:
SPIE Proceedings.
We undertook a phase I dose-escalation study of verteporfin photodynamic therapy (PDT) in 15 patients with locally advanced pancreatic cancer. Needle placement and laser delivery were technically successful in all patients. Thirteen patients were tre
Autor:
Alice Gillams, B. W. Pogue, M. T. Huggett, R. N. B. Baddeley, GJ Webster, Laurence Lovat, Stephen P. Pereira, Neomal S. Sandanayake, Sg Bown, Tayyaba Hasan
Publikováno v:
SPIE Proceedings.
The diagnosis and treatment of pancreaticobiliary malignancy is of major interest to our group. Building on prior work, we undertook a phase I study of verteporfin photodynamic therapy in patients with locally advanced, unresectable, pancreatic cance
Autor:
Tayyaba Hasan, Sg Bown, B. W. Pogue, Neomal S. Sandanayake, Stephen P. Pereira, M. T. Huggett
Publikováno v:
SPIE Proceedings.
Pancreatic adenocarcinoma ranks as the fourth most common cause of cancer death in the USA. Patients usually present late with advanced disease, limiting attempted curative surgery to 10% of cases. Overall prognosis is poor with one-year survival rat
Autor:
B. W. Pogue, SP Pereira, Sandy Mosse, Michael Jermyn, Tayyaba Hasan, E. Kent, Matthew T. Huggett, Sg Bown, Alice Gillams
Publikováno v:
Pancreatology. 13:e2-e3
Publikováno v:
Photochemistry and photobiology. 74(6)
In this study the endogenous fluorescence signal attributed to reduced nicotinamide adenine dinucleotide (NADH) has been measured in response to photodynamic therapy (PDT)-induced damage. Measurements on cells in vitro have shown that NADH fluorescen
Publikováno v:
Photochemistry and photobiology. 74(5)
Photodynamic therapy (PDT) with verteporfin provides a reliable way to destroy malignant tissues. Changes in the blood flow and oxygen partial pressure (pO2) during verteporfin-PDT were studied here in the tumor tissue of the rat mammary R3230Ac carc