Zobrazeno 1 - 2
of 2
pro vyhledávání: '"B W, Strassle"'
Autor:
G T, Whiteside, J M, Dwyer, J E, Harrison, C E, Beyer, T, Cummons, L, Manzino, L, Mark, G H, Johnston, B W, Strassle, A, Adedoyin, P, Lu, M J, Piesla, C M, Pulicicchio, J C L, Erve, B J, Platt, Z A, Hughes, K E, Rogers, D C, Deecher, E J, Trybulski, J D, Kennedy, P, Zhang, L, Leventhal
Publikováno v:
British journal of pharmacology. 160(5)
Antidepressants, which raise the CNS concentrations of 5-HT and noradrenaline, are frequently used in the treatment of chronic pain; however, it is not known if increasing CNS noradrenaline levels alone is sufficient for efficacy, in part resulting f
Autor:
B, Bingham, P G, Jones, A J, Uveges, S, Kotnis, P, Lu, V A, Smith, S-C, Sun, L, Resnick, M, Chlenov, Y, He, B W, Strassle, T A, Cummons, M J, Piesla, J E, Harrison, G T, Whiteside, J D, Kennedy
Publikováno v:
British journal of pharmacology. 151(7)
Racemic (R,S) AM1241 is a cannabinoid receptor 2 (CB(2))-selective aminoalkylindole with antinociceptive efficacy in animal pain models. The purpose of our studies was to provide a characterization of R,S-AM1241 and its resolved enantiomers in vitro