Zobrazeno 1 - 9
of 9
pro vyhledávání: '"B W, Sharp"'
Publikováno v:
ChemInform. 24
The potent potassium channel opener, 4 , RP 65479, has been synthesised from the key intermediate, 2-(3-pyridyl)cyclohexanone, 8 .
Autor:
B. W. Sharp, M. P. Toft, Hart Terance William, Walsh Roger John Aitchison, D. Guillochon, G. Perrier, B. Vacher
Publikováno v:
ChemInform. 24
The potent, homochiral, potassium channel opener, RP 66471, has been synthesised and shown to possess the (1R, 2S) configuration.
Autor:
I. Warner, Michael B. Hursthouse, Nigel Vicker, D. E. Hibbs, C. J. Hardy, S. M. Fairway, Andrew David Morley, B. W. Sharp, C. P. Adams
Publikováno v:
ChemInform. 27
The total synthesis of the fungal metabolite balanol, a potent inhibitor of protein kinase C, is described. The synthesis includes a novel synthesis of 3-amino-4-hydroxyazepanes via a directed ring expansion of 3-bromopiperidin-4-ones.
Autor:
Hart Terance William, B. W. Sharp, M. P. Toft, B. Vacher, G. Perrier, D. Guillochon, Walsh Roger John Aitchison
Publikováno v:
Tetrahedron Letters. 33:7211-7214
The potent, homochiral, potassium channel opener, RP 66471, has been synthesised and shown to possess the (1R, 2S) configuration.
Publikováno v:
Tetrahedron Letters. 33:5117-5120
The potent potassium channel opener, 4 , RP 65479, has been synthesised from the key intermediate, 2-(3-pyridyl)cyclohexanone, 8 .
Autor:
S. M. Fairway, I. Warner, B. W. Sharp, Nigel Vicker, C. P. Adams, Michael B. Hursthouse, Andrew David Morley, C. J. Hardy, D. E. Hibbs
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :2355
The total synthesis of the fungal metabolite balanol, a potent inhibitor of protein kinase C, is described. The synthesis includes a novel synthesis of 3-amino-4-hydroxyazepanes via a directed ring expansion of 3-bromopiperidin-4-ones.
Publikováno v:
Chemistryindustry. 2
Publikováno v:
Chemischer Informationsdienst. Organische Chemie. 2
Publikováno v:
Journal of the Chemical Society C: Organic. :2449
Pyrido[1,2-b][2,4]benzodiazepin-6(11H)-one and its 1,2,3,4,4a,5-hexahydro-derivative have been prepared. Some chemical properties and reactions of these novel ring systems have been explored.