Zobrazeno 1 - 10
of 62
pro vyhledávání: '"B W, Ozanne"'
Autor:
Douglas Fenton-Lee, R C Richards, A Walsh, J R Reeves, A M McNicol, Timothy G. Cooke, B W Ozanne
Publikováno v:
Journal of Histochemistry & Cytochemistry. 42:307-314
We developed a sensitive EGF receptor detection method for frozen tissue sections using biotinylated EGF as the primary reagent. The method was directly compared with an immunohistochemical technique based on an anti-EGF receptor monoclonal antibody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f05efd36f5847b8a5b4b0647a2e578b4
https://doi.org/10.1177/42.3.8308248
https://doi.org/10.1177/42.3.8308248
Publikováno v:
Europe PubMed Central
Scopus-Elsevier
Scopus-Elsevier
The c-fos and c-jun proto-oncogenes encode components of the transcription factor AP-1. To determine whether transformation by the v-fos or v-jun oncogene results in alterations in the level or regulation of this factor, we have characterized AP-1 DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d3eef7a73edc0a8be99006ee2690536
https://doi.org/10.1128/jvi.67.9.5487-5495.1993
https://doi.org/10.1128/jvi.67.9.5487-5495.1993
Autor:
Lindsay C. Spender, Gareth J. Inman, Jonas Larsson, Robert Grosse, B W Ozanne, Y M Fleming, Stefan Karlsson, G J Ferguson
Publikováno v:
Oncogene. 28(7)
Transforming growth factor beta-1 (TGF-beta) acts as both a tumour suppressor and a tumour promoter in a context-dependent manner. The tumour-promoting activities of TGF-beta are likely to result from a combination of Smad and non-Smad signalling pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16fcc47157d2683e74aec2444833972a
https://pubmed.ncbi.nlm.nih.gov/19079344
https://pubmed.ncbi.nlm.nih.gov/19079344
Publikováno v:
The Journal of pathology. 210(3)
HER2 status is routinely tested using immunohistochemistry or FISH following the licensing of a therapeutic agent targeting HER2. However, neither of these methods provides quantitative information relating to the 70-80% of patients with levels of ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dd8d03b60a63ee264206de795b66401
https://pubmed.ncbi.nlm.nih.gov/16981252
https://pubmed.ncbi.nlm.nih.gov/16981252
Publikováno v:
Blood. 90(1)
Human CD23 is a 45-kD type II membrane glycoprotein, which functions as a low-affinity receptor for IgE and as a ligand for the CD21 and CD11b/CD11c differentiation antigens. CD23 is released from the surface of cells as soluble fragments, and a 25-k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1d747e79ab69c1958c0c44a17cd606a7
https://pubmed.ncbi.nlm.nih.gov/9207458
https://pubmed.ncbi.nlm.nih.gov/9207458
Publikováno v:
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 44(11)
The relationship between expression of the c-erbB-2 proto-oncogene and the biology of breast cancer has been investigated widely, most studies using immunohistochemistry in formalin-fixed, paraffin-embedded tissues. This technique is at best semiquan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7396785f9b1e1125c56e7192829f72b8
https://pubmed.ncbi.nlm.nih.gov/8918900
https://pubmed.ncbi.nlm.nih.gov/8918900
Publikováno v:
Cancer research. 56(16)
Epidermal growth factor receptor (EGFR) expression by human breast cancer has been shown to predict poor patient outcome, as has amplification of the c-erbB-2 proto-oncogene. We have developed a quantitative immunohistochemical method for measuring p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::508f1c59a28abcf30e2b3112459030ed
https://pubmed.ncbi.nlm.nih.gov/8706030
https://pubmed.ncbi.nlm.nih.gov/8706030
Publikováno v:
Oncogene. 13(2)
Increased AP-1 DNA-binding activity, in the context of TRE-binding, is not a consequence of Fos transformation. In this report we investigate the possibility of a change in binding site preference by vFosAP-1 compared with AP-1 from an untransformed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3f2d172943c6afc8ac103887b751568e
https://pubmed.ncbi.nlm.nih.gov/8710367
https://pubmed.ncbi.nlm.nih.gov/8710367
Publikováno v:
Oncogene. 11(12)
The recent discovery of the vaccinia virus protein phosphatase VH1, and its mammalian counterparts has highlighted a novel subfamily of protein tyrosine phosphatases that exhibit dual specificity toward phosphotyrosine- and phosphoserine/threonine-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3ec01fe019d106d142aac2fcd31a5e4b
https://pubmed.ncbi.nlm.nih.gov/8545112
https://pubmed.ncbi.nlm.nih.gov/8545112
Publikováno v:
Oncogene. 9(12)
Fos oncoproteins transform cells by functioning as transcription factors. Over-expression of c-fos results in minimal morphological transformation while the two viral isolates, FBJ and FBR v-fos, result in full morphological transformation. Fos-trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f8d400333286f1ab3d06c90a2cdf25b6
https://pubmed.ncbi.nlm.nih.gov/7970719
https://pubmed.ncbi.nlm.nih.gov/7970719