Zobrazeno 1 - 10
of 14
pro vyhledávání: '"B T Kurien"'
Publikováno v:
The Journal of Immunology. 156:4059-4066
Systemic lupus erythematosus is characterized by the production of Abs to ribonucleoproteins, including Ro (or SS-A) and La (or SS-B). The mechanism by which these autoantibodies arise is unknown. We have immunized rabbits with peptides from the sequ
Autor:
B T, Kurien
Publikováno v:
Singapore medical journal. 47(8)
Publikováno v:
Scandinavian journal of immunology. 56(5)
Antibodies binding the Ro (or SSA) and La (or SBB) proteins are commonly found in a high proportion of sera from patients with systemic lupus erythematosus or Sjögren's syndrome. The mechanism by which these autoantibodies arise is not known. Others
Publikováno v:
Indian journal of biochemistrybiophysics. 38(4)
A simple procedure for the purification of tryptic peptides, prior to mass spectrometric analysis, using polyvinylidene fluoride membrane (PVDF) is described. The sensitivity of mass spectrometric analysis is such that minor impurities in tryptic pep
Publikováno v:
The Journal of rheumatology. 27(1)
To examine a well characterized group of patients with systemic lupus erythematosus (SLE) for anti-calreticulin.The sera of 77 patients with SLE were studied by immunodiffusion, solid phase immunoassay, and immunoblot for antibodies against ribonucle
Autor:
B T, Kurien, R H, Scofield
Publikováno v:
Indian journal of biochemistrybiophysics. 35(6)
For the detection of proteins on sodium dodecyl sulphate-polyacrylamide gel electrophoresis, Coomassie blue is used commonly on account of its simplicity and reliability. In this report we show that enhanced heat, in addition to dramatically decreasi
Publikováno v:
Arthritis and rheumatism. 42(5)
Immunization with peptide fragments of autoantigens may lead to an immune response at both the T and B cell level that is directed not only at the immunogen, but also at the autoantigen from which the peptide came. In addition, a complex multicompone
Autor:
B T, Kurien, R H, Scofield
Publikováno v:
Indian journal of biochemistrybiophysics. 35(1)
Multiple nuclear dot (MND), or pseudocentromere, anti-nuclear antibody (ANA) is an uncommon pattern associated primarily with primary biliary cirrhosis (PBC) and anti-mitochondrial antibody (AMA). A 53 kDa antigen with an apparent molecular mass of 1
Publikováno v:
The Journal of rheumatology. 25(7)
We characterized the development of the anti-centromere antibody in a patient prior to the development of CREST (calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, telangiectasias) symptoms. Sodium dodecyl sulfate-polyacrylamide
Publikováno v:
Journal of clinical immunology. 17(3)
A gel filtration method was developed to estimate the number of conformational epitopes on the 60-kD Ro antigen. Anti-Ro Fab or Fab' was incubated with native Ro antigen at different ratios and the Stokes radius molecular weight of complexes was esti