Zobrazeno 1 - 10
of 14
pro vyhledávání: '"B T Kren"'
Publikováno v:
Journal of Lipid Research, Vol 37, Iss 3, Pp 540-550 (1996)
We recently demonstrated that the formation of delta 22-bile acids is a quantitatively major pathway for normal bile acid synthesis in the adult male Sprague-Dawley rat. This pathway is specific for 7 beta-hydroxy bile acids and, when ursodeoxycholic
Externí odkaz:
https://doaj.org/article/369ca579f77749b888d2ec191d5366d9
Publikováno v:
Current opinion in molecular therapeutics. 3(4)
We are now approaching the reality of success in gene therapy as our knowledge of the genetic basis of disease continues to grow, coupled with improved delivery methods for therapeutic nucleic acid molecules. It is apparent that gene therapy can be d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8846ece5fece17cc1289ac8933821ba2
https://pubmed.ncbi.nlm.nih.gov/11525556
https://pubmed.ncbi.nlm.nih.gov/11525556
Publikováno v:
The Journal of biological chemistry. 274(15)
Chimeric RNA/DNA oligonucleotides have been shown to promote single nucleotide exchange in genomic DNA. A chimeric molecule was designed to introduce an A to C nucleotide conversion at the Ser365 position of the rat factor IX gene. The oligonucleotid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b30fada477190065f37d1d5bcca17dee
https://pubmed.ncbi.nlm.nih.gov/10187800
https://pubmed.ncbi.nlm.nih.gov/10187800
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 7(12)
Liver regeneration (LR) after 70% partial hepatectomy (PH) represents a unique in vivo model of cell cycle and gene regulation. This study was conducted to characterize apoptosis-associated gene expression during LR. The results indicated that transc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::083e9102b520b0c854933eed3584da6b
https://pubmed.ncbi.nlm.nih.gov/8959331
https://pubmed.ncbi.nlm.nih.gov/8959331
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 7(7)
Cyclin genes and their products are important regulatory participants in the eukaryotic cell cycle. It is well established that cyclin B1 protein forms a complex with cyclin-dependent kinase 1 (CDK1), which, when activated, initiates mitosis. We have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d3b6412ce05f914b055176fa659d0bfb
https://pubmed.ncbi.nlm.nih.gov/8809408
https://pubmed.ncbi.nlm.nih.gov/8809408
Publikováno v:
Oncogene. 12(9)
Transforming growth factor-beta1 (TGF-beta1) can induce rapid growth arrest and apoptosis in hepatic cells. Its growth suppressive effects appear to be linked to decreased phosphorylation of the protein product of the retinoblastoma gene, pRb. To cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f2a5bc11f0bf5facba2818d3833a9bb9
https://pubmed.ncbi.nlm.nih.gov/8649852
https://pubmed.ncbi.nlm.nih.gov/8649852
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 6(11)
Protein expression of the retinoblastoma (Rb) tumor suppressor gene product was examined by immunoblot analysis of nuclei isolated from regenerating rat liver after 70% partial hepatectomy (PH). Levels were almost undetectable in quiescent 0-h livers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5c288337445da65b9af2a8cf28a7a3b0
https://pubmed.ncbi.nlm.nih.gov/8562485
https://pubmed.ncbi.nlm.nih.gov/8562485
Publikováno v:
Hepatology (Baltimore, Md.). 22(4 Pt 1)
We examined the effects of feeding deoxycholic acid (1% and 0.4% of diet), alone and in combination with ursodeoxycholic acid, on serum and biliary bile acid concentrations, hepatic morphology, and the activities and steady-state messenger RNA (mRNA)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::28cd39d6f177205c0cf8f7bf271e0890
https://pubmed.ncbi.nlm.nih.gov/7557873
https://pubmed.ncbi.nlm.nih.gov/7557873
Publikováno v:
Hepatology (Baltimore, Md.). 19(5)
This study characterizes the mRNA expression of the retinoblastoma tumor suppressor gene in regenerating rat liver during 96 hr after 70% partial hepatectomy. A 960-bp BglII-OxaNI fragment of murine retinoblastoma cDNA was used to probe Northern blot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a9918a75113a681f88fd037f7640b9bd
https://pubmed.ncbi.nlm.nih.gov/8175144
https://pubmed.ncbi.nlm.nih.gov/8175144
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 5(1)
The growing family of cyclin genes and their products have been identified as important regulatory participants in the eukaryotic cell cycle. Cyclin proteins are currently postulated to act at the G1 restriction point, entry and exit of S phase, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6ded25c27e3fda60800564c8c237ed41
https://pubmed.ncbi.nlm.nih.gov/8123599
https://pubmed.ncbi.nlm.nih.gov/8123599