Zobrazeno 1 - 10
of 33
pro vyhledávání: '"B T, Hinton"'
Autor:
B T, Hinton, T G, Cooper
Publikováno v:
Handbook of experimental pharmacology. (198)
The epididymis is an excellent target for the development of a male contraceptive. This is because the process of sperm maturation occurs in this organ; spermatozoa become motile and are able to recognise and fertilise an egg once they have traversed
Publikováno v:
Journal of andrology. 22(4)
Autor:
R J, Lye, B T, Hinton
Publikováno v:
Asian journal of andrology. 2(1)
Sperm mature and acquire the capacity for fertilization during their transit through the epididymis, however little is known of the molecular events that comprise sperm maturation. Recent advances in transgenic mouse technology hold promise for illum
Autor:
B T, Hinton
Publikováno v:
Journal of andrology. 21(2)
Publikováno v:
Biology of reproduction. 60(3)
Gamma-glutamyl transpeptidase (GGT) mRNA-IV and polyomavirus enhancer activator 3 (PEA3) mRNA are highly expressed in the initial segment of the rat epididymis, and both are regulated by testicular factors. PEA3 protein in rat initial segment nuclear
Publikováno v:
Journal of andrology. 19(1)
Reactive oxygen species (ROS) have a powerful cytotoxic effect on spermatozoa and have been implicated in spermatozoal dysfunction and male infertility. gamma-Glutamyl transpeptidase (GGT) is essential to the metabolism of the antioxidant glutathione
Publikováno v:
Biology of reproduction. 58(1)
The objective of this study was to test the hypothesis that gamma-glutamyl transpeptidase (GGT) catalytic activity and protein level in the initial segment are regulated by testicular factors. In the rat epididymis, levels of GGT catalytic activity w
Autor:
D B, Rudolph, B T, Hinton
Publikováno v:
Journal of andrology. 18(5)
Gamma-glutamyl transpeptidase (GGT) is an enzyme believed to play a role in the protection of maturing spermatozoa in the epididymis. Our previous studies have shown that four GGT mRNAs (I-IV) transcribed from the single-copy rat GGT gene are differe
Publikováno v:
Biology of reproduction. 57(1)
Gamma-glutamyl transpeptidase (GGT) mRNA-IV is highly expressed in the initial segment of the rat epididymis and is regulated by testicular factors. The promoter region for GGT mRNA-IV contains five conserved polyomavirus enhancer activator 3 (PEA3)-
Publikováno v:
Journal of andrology. 17(2)
Sympathetic denervation of the rat cauda epididymidis by surgical removal of the inferior mesenteric ganglion (IMG) results in an excessive accumulation of sperm in the cauda epididymidis as well as significant changes in cauda sperm motility and cau