Zobrazeno 1 - 10 of 266 pro vyhledávání: '"B Schroer"'
1
Akademický článek
Platelet-derived exerkine CXCL4/platelet factor 4 rejuvenates hippocampal neurogenesis and restores cognitive function in aged mice
Autor: Odette Leiter, David Brici, Stephen J. Fletcher, Xuan Ling Hilary Yong, Jocelyn Widagdo, Nicholas Matigian, Adam B. Schroer, Gregor Bieri, Daniel G. Blackmore, Perry F. Bartlett, Victor Anggono, Saul A. Villeda, Tara L. Walker
Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract The beneficial effects of physical activity on brain ageing are well recognised, with exerkines, factors that are secreted into the circulation in response to exercise, emerging as likely mediators of this response. However, the source and i
Externí odkaz: https://doaj.org/article/d8e83ff214284a649830da1f3c2ec9ee
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2
Akademický článek
The platelet transcriptome and proteome in Alzheimer’s disease and aging: an exploratory cross-sectional study
Autor: Diana M. Bessa de Sousa, Rodolphe Poupardin, Saul A. Villeda, Adam B. Schroer, Thomas Fröhlich, Vanessa Frey, Wolfgang Staffen, Heike Mrowetz, Barbara Altendorfer, Michael S. Unger, Bernhard Iglseder, Bernhard Paulweber, Eugen Trinka, Janne Cadamuro, Martin Drerup, Katharina Schallmoser, Ludwig Aigner, Kathrin M. Kniewallner
Publikováno v: Frontiers in Molecular Biosciences, Vol 10 (2023)
Introduction: Alzheimer’s disease (AD) and aging are associated with platelet hyperactivity. However, the mechanisms underlying abnormal platelet function in AD and aging are yet poorly understood.Methods: To explore the molecular profile of AD and
Externí odkaz: https://doaj.org/article/636238625d2e475984b6becd06a2383c
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3
Akademický článek
Platelets Give a Running Start to Adult Hippocampal Neurogenesis
Autor: Adam B. Schroer, Alana M. Horowitz, Saul A. Villeda
Publikováno v: Stem Cell Reports, Vol 12, Iss 4, Pp 643-646 (2019)
Exercise boosts neural stem and progenitor cell proliferation and differentiation in the dentate gyrus region of the hippocampus. In this issue of Stem Cell Reports, Leiter et al. (2019) identify acute exercise-induced platelet activation and platele
Externí odkaz: https://doaj.org/article/dc6331dac44c46b9ae763d58e8a47bae
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4
Akademický článek
A role for Regulator of G protein Signaling-12 (RGS12) in the balance between myoblast proliferation and differentiation.
Autor: Adam B Schroer, Junaith S Mohamed, Melinda D Willard, Vincent Setola, Emily Oestreich, David P Siderovski
Publikováno v: PLoS ONE, Vol 14, Iss 8, p e0216167 (2019)
Regulators of G Protein Signaling (RGS proteins) inhibit G protein-coupled receptor (GPCR) signaling by accelerating the GTP hydrolysis rate of activated Gα subunits. Some RGS proteins exert additional signal modulatory functions, and RGS12 is one s
Externí odkaz: https://doaj.org/article/91c5797ef9b144e89da277b344d6565d
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6
The stability of tastant detection by mouse lingual chemosensory tissue requires Regulator of G protein Signaling-21 (RGS21)
Autor: Paul D. Chantler, Joshua D Gross, Adam B. Schroer, Kayla W. Branyan, Adam J. Kimple, David P. Siderovski, Aurelie Vandenbeuch
Publikováno v: Chem Senses
The T1R and T2R families of G protein-coupled receptors (GPCRs) initiate tastant perception by signaling via guanine nucleotide exchange and hydrolysis performed by associated heterotrimeric G proteins (Gαβγ). Heterotrimeric G protein signal termi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16261d7e293f641cf2b3263f907eeb90
https://pubmed.ncbi.nlm.nih.gov/34718440
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7
Akademický článek
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