Zobrazeno 1 - 10
of 30
pro vyhledávání: '"B S, Zhorov"'
Autor:
B S, Zhorov, D B, Tikhonov
Publikováno v:
Current topics in membranes. 78
Voltage-gated sodium channels are targets for many toxins and medically important drugs. Despite decades of intensive studies in industry and academia, atomic mechanisms of action are still not completely understood. The major cause is a lack of high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4f3361417213ee367f03630c56faa2ad
https://pubmed.ncbi.nlm.nih.gov/27586283
https://pubmed.ncbi.nlm.nih.gov/27586283
Publikováno v:
Zhurnal evoliutsionnoi biokhimii i fiziologii. 52(1)
An integral part of modern evolutionary biology is comparative analysis of structure and function of macromolecules such as proteins. The first and critical step to understand evolution of homologous proteins is their amino acid sequence alignment. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::214e97ea8d4cd4da284fd164134d2d79
https://pubmed.ncbi.nlm.nih.gov/27220237
https://pubmed.ncbi.nlm.nih.gov/27220237
Autor:
E. V. Rozengart, N. E. Basova, B. S. Zhorov, S. N. Moralev, V. S. Saakov, A. A. Suvorov, A. E. Khovanskikh
Publikováno v:
Journal of Evolutionary Biochemistry and Physiology. 39:393-404
Study of spatial structure of biologically active guanidine derivatives by the method of molecular mechanics has shown that in an anticoccidial drug, 1,3-bis ( p-chlorobenzylidenamino)guanidine (Cl-BAG) the most preferable are convolute conformations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::448ff71aa13ca2180181d5996516210c
https://doi.org/10.1023/b:joey.0000010235.00798.98
https://doi.org/10.1023/b:joey.0000010235.00798.98
Autor:
B S, Zhorov
Publikováno v:
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. 97(7)
Ion channels in cell membranes are targets for a multitude of ligands including naturally occurring toxins, illicit drugs, and medications used to manage pain and treat cardiovascular, neurological, autoimmune, and other health disorders. In the past
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b6e517bd4aa3114b0117ae623af4afc0
https://pubmed.ncbi.nlm.nih.gov/21961291
https://pubmed.ncbi.nlm.nih.gov/21961291
Autor:
E V, Rozengart, N E, Basova, B S, Zhorov, S N, Moralev, V S, Saakov, A A, Suvorov, A E, Khovanskikh
Publikováno v:
Zhurnal evoliutsionnoi biokhimii i fiziologii. 39(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d378b4457f7e6f86c19d199b13dfb0cb
https://pubmed.ncbi.nlm.nih.gov/14520894
https://pubmed.ncbi.nlm.nih.gov/14520894
Publikováno v:
Journal of peptide science : an official publication of the European Peptide Society. 6(2)
The biologically relevant conformation of substance P is likely to be dictated by the lipid milieu wherein the hormone would interact with its receptor. Assuming that specific constraints to the hormone structure may be imparted by its interaction wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b5d5b55db7b567b3e3b8fbf691874164
https://pubmed.ncbi.nlm.nih.gov/10718128
https://pubmed.ncbi.nlm.nih.gov/10718128
Autor:
B S, Zhorov, S X, Lin
Publikováno v:
Proteins. 38(4)
17 beta-Estradiol (E2) is a potent stimulator of certain forms of breast cancer. The final step of E2 biosynthesis is catalyzed by the estrogenic 17 beta-hydroxysteroid dehydrogenase (17 beta-HSD1), which is an important target for anti-cancer drugs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bda797bee2c7b6c89120c2d0a8631079
https://pubmed.ncbi.nlm.nih.gov/10707028
https://pubmed.ncbi.nlm.nih.gov/10707028
Publikováno v:
Bioorganicheskaia khimiia. 25(5)
A conformational variability of the collagen triple helix was studied with the methods of molecular mechanics. The Rich-Crick model with one hydrogen bond per tripeptide fragment or the model with two hydrogen bonds per tripeptide fragment were used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5a4da48a6a6732360aaa487ab839366f
https://pubmed.ncbi.nlm.nih.gov/10495892
https://pubmed.ncbi.nlm.nih.gov/10495892
Publikováno v:
Biopolymers. 40(5)
Drastic changes in the CD and fluorescence spectra of oxytocin [cyclo(Cys1-Tyr2-Ile3-Gln4-Asn5-Cys6)-Pro7-Leu8-Gly 9-NH2] occur on binding Ca2+ in trifluoroethanol (Ananthanarayanan and Brimble, preceding paper). To further characterize the conformat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ab6aae852cc4c7ad2732f825b9c85e72
https://pubmed.ncbi.nlm.nih.gov/9062068
https://pubmed.ncbi.nlm.nih.gov/9062068
Publikováno v:
Bioorganicheskaia khimiia. 18(4)
All equilibrium conformations of 12 anti-acetylcholinesterase organophosphorus inhibitors were calculated by the molecular mechanics method. The accessibility of the phosphorus atom of the inhibitors for interactions with the nucleophilic group at th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::13e737f11a9df05790f77b14f054625d
https://pubmed.ncbi.nlm.nih.gov/1503573
https://pubmed.ncbi.nlm.nih.gov/1503573