Zobrazeno 1 - 10
of 54
pro vyhledávání: '"B S, Katzenellenbogen"'
Autor:
Kevin T. O'Byrne, B S Katzenellenbogen, Xiao Feng Li, J A Katzenellenbogen, James E. Bowe, David Sugden
Publikováno v:
Journal of Neuroendocrinology. 15:105-108
Phytoestrogens can produce inhibitory effects on gonadotropin secretion in both animals and humans, although little is known about the mechanisms and the role of direct action on oestrogen receptors (ER) in this process. We examined the effect of cou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4622ff2867e836949a88746b79ad29a1
https://doi.org/10.1046/j.1365-2826.2003.00991.x
https://doi.org/10.1046/j.1365-2826.2003.00991.x
Autor:
J C, Reese, B S, Katzenellenbogen
Publikováno v:
Molecular and Cellular Biology. 12:4531-4538
We describe an assay employing the competitive binding of estrogen receptor (ER) with basal transcription factors on a constitutive promoter (cytomegalovirus-hormone response element[s]-chloramphenicol acetyltransferase [CMV-(HRE)n-CAT, containing a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60640a2792621fc364da92cc221d759e
https://doi.org/10.1128/mcb.12.10.4531-4538.1992
https://doi.org/10.1128/mcb.12.10.4531-4538.1992
Autor:
M J E Walenkamp, J Wang, B S Katzenellenbogen, Ryan J. Hartmaier, Steffi Oesterreich, Alexandra S. Richter, J.M. Wit
Publikováno v:
Journal of pediatric endocrinologymetabolism : JPEM. 22(8)
Background Premature thelarche is defined as breast development before 8 years of age. This is most often caused by central hormone disregulation and is accompanied by concurrent bone maturation. However, we present a case of premature thelarche with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::508984a38e61183be53d29e9bf58baa1
https://pubmed.ncbi.nlm.nih.gov/19845126
https://pubmed.ncbi.nlm.nih.gov/19845126
Publikováno v:
Journal of neuroendocrinology. 15(2)
Phytoestrogens can produce inhibitory effects on gonadotropin secretion in both animals and humans, although little is known about the mechanisms and the role of direct action on oestrogen receptors (ER) in this process. We examined the effect of cou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c856b9bb33a372652823b9e6c96f7b57
https://pubmed.ncbi.nlm.nih.gov/12535152
https://pubmed.ncbi.nlm.nih.gov/12535152
Autor:
S, Kousteni, T, Bellido, L I, Plotkin, C A, O'Brien, D L, Bodenner, L, Han, K, Han, G B, DiGregorio, J A, Katzenellenbogen, B S, Katzenellenbogen, P K, Roberson, R S, Weinstein, R L, Jilka, S C, Manolagas
Publikováno v:
Cell. 104(5)
The relationship of the classical receptors and their transcriptional activity to nongenotropic effects of steroid hormones is unknown. We demonstrate herein a novel paradigm of sex steroid action on osteoblasts, osteocytes, embryonic fibroblasts, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::996bb4bf240b4b0816c344ce8b8ddf8c
https://pubmed.ncbi.nlm.nih.gov/11257226
https://pubmed.ncbi.nlm.nih.gov/11257226
Triarylpyrazoles with basic side chains: development of pyrazole-based estrogen receptor antagonists
Autor:
S R, Stauffer, Y R, Huang, Z D, Aron, C J, Coletta, J, Sun, B S, Katzenellenbogen, J A, Katzenellenbogen
Publikováno v:
Bioorganicmedicinal chemistry. 9(1)
Recently, we developed a novel triaryl-substituted pyrazole ligand system that has high affinity for the estrogen receptor (ER) (Fink, B. E.: Mortenson, D. S.: Stauffer, S. R.; Aron, Z. D.: Katzenellenbogen, J. A. Chem. Biol. 1999, 6, 205). Subsequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8b5eb549f941c6598fb193498dcafcab
https://pubmed.ncbi.nlm.nih.gov/11197335
https://pubmed.ncbi.nlm.nih.gov/11197335
Autor:
M B, Martin, T F, Franke, G E, Stoica, P, Chambon, B S, Katzenellenbogen, B A, Stoica, M S, McLemore, S E, Olivo, A, Stoica
Publikováno v:
Endocrinology. 141(12)
This study examines whether the serine/threonine protein kinase, Akt, is involved in the cross-talk between epidermal growth factor (EGF) and insulin-related growth factor I (IGF-I) receptors and ER-alpha. Treatment of MCF-7 cells with either EGF or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::79e1d03d15a5ad28bd6dc8741f9e35d5
https://pubmed.ncbi.nlm.nih.gov/11108261
https://pubmed.ncbi.nlm.nih.gov/11108261
Publikováno v:
The Journal of biological chemistry. 274(47)
Estrogen receptor alpha (ERalpha) is a soluble protein that mediates the effects of the gonadal estrogens such as 17beta-estradiol. Upon ligand binding, a cytoplasmic pool of ERalpha translocates to the nucleus, where it acts as a transcription facto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c8fd1d4dc5a574bbbcd4866d58c37db7
https://pubmed.ncbi.nlm.nih.gov/10559241
https://pubmed.ncbi.nlm.nih.gov/10559241
Publikováno v:
Endocrinology. 139(11)
We have studied the two estrogen receptor (ER) subtypes, ER alpha and ER beta, and chimeric constructs with ER alpha and ER beta to examine the bioactivities of these receptors and their responses to estrogen and antiestrogen ligands. Transcriptional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::23f128f2a93e1d6a24366ade5b1a7946
https://pubmed.ncbi.nlm.nih.gov/9794460
https://pubmed.ncbi.nlm.nih.gov/9794460
Publikováno v:
Breast cancer research and treatment. 44(1)
Antiestrogens have proven to be highly effective in the treatment of hormone-responsive breast cancer. However, resistance to antiestrogen therapy often develops. In addition, although tamoxifen-like antiestrogens are largely inhibitory and function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2af831a1f5ad304e1749f0e6f9296e6d
https://pubmed.ncbi.nlm.nih.gov/9164675
https://pubmed.ncbi.nlm.nih.gov/9164675