Zobrazeno 1 - 10
of 50
pro vyhledávání: '"B S, Jayashree"'
Publikováno v:
Advances in Pharmacological Sciences, Vol 2018 (2018)
Alteration of epigenetic enzymes is associated with the pathophysiology of colon cancer with an overexpression of histone deacetylase 8 (HDAC8) enzyme in this tissue. Numerous reports suggest that targeting HDAC8 is a viable strategy for developing n
Externí odkaz:
https://doaj.org/article/66790d98604b42f28941865205594ba5
Autor:
B. S. Jayashree, Aravinda Pai
Publikováno v:
Indian Journal of Pharmaceutical Education and Research. 53:s313-s324
Aim/Background: Chalcones are one of the important class of compounds possessing a wide range of biological properties [Dinmock 1999, Go 2005]. One of the extensive area in research on chalcones is expressed in terms of their ability to act on variou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea78957f8dc7e906bab32505ae4d904e
https://doi.org/10.5530/ijper.53.3s.101
https://doi.org/10.5530/ijper.53.3s.101
Publikováno v:
Mini-Reviews in Organic Chemistry. 16:377-391
Flavonoids constitute a large group of polyphenolic compounds that are known to have antioxidant properties, through their free radical scavenging abilities. They possess a chromone (γ- benzopyrone) moiety, responsible for eliciting many pharmacolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69b9eca62c2f6d22649f6cf1400175c0
https://doi.org/10.2174/1570193x15666180418154510
https://doi.org/10.2174/1570193x15666180418154510
Autor:
Yogendra Nayak, Venkatachalam Hillemane, Vijay Kumar Daroji, B. S. Jayashree, M. K. Unnikrishnan
Publikováno v:
The Scientific World Journal, Vol 2014 (2014)
Benzopyrones are proven antidiabetic drug candidate in diabetic drug discovery. In this view novel synthetic benzopyrone analogues were selected for testing in experimental diabetes. Type 2 diabetes (T2D) was induced in Wistar rats by streptozotocin
Externí odkaz:
https://doaj.org/article/471ec98edabc43e08bd53acf9161f5be
Publikováno v:
Journal of Diabetes and its Complications. 32:524-530
Diabetes is a chronic metabolic disorder that poses a global burden to healthcare. Increasing incidence of diabetes-related complications in the affected population includes a delay in wound healing that often results in non-traumatic limb amputation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6978fc25c0e05ac511d1658b902eaa11
https://doi.org/10.1016/j.jdiacomp.2018.01.015
https://doi.org/10.1016/j.jdiacomp.2018.01.015
Publikováno v:
Acta Crystallographica Section E, Vol 67, Iss 6, Pp o1492-o1492 (2011)
In the title compound, C17H16O2, the dihedral angle between the aromatic rings is 5.12 (13)° and an intramolecular O—H...O hydrogen bond generates an S(6) ring.
Externí odkaz:
https://doaj.org/article/c23fe18d63b64fb792cdcd3308d399c0
Publikováno v:
Acta Crystallographica Section E, Vol 67, Iss 4, Pp o829-o829 (2011)
The molecule of the title compound, C17H16O3, exists in the E conformation with respect to the central C=C bond, is almost planar(r.m.s. deviation = 0.003 Å) and has an intramolecular O—H...O hydrogen bond, which generates an S(6) ring. In the cry
Externí odkaz:
https://doaj.org/article/1fd5803515c446be878601cab05e6f88
Publikováno v:
Acta Crystallographica Section E, Vol 66, Iss 6, Pp o1385-o1385 (2010)
In the structure of the title compound, C15H14O2S, the benzene ring is nearly coplanar with the thiophene ring. The hydroxy group substituted at C2 position is in an antiperiplanar conformation with respect to the phenyl ring. The crystal structure e
Externí odkaz:
https://doaj.org/article/35bc8eea7c0b4c6ebf6708d287731c6f
Publikováno v:
INDIAN DRUGS. 54:7-14
A series of novel flavone-4-oximes were synthesized by the oximation of substituted flavones. The synthesized compounds were characterized by various spectrochemical methods including IR, MS and NMR spectroscopy. Out of the 14 test compounds screened
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::561d770ed3368fb5d997e17f6c53b2ab
https://doi.org/10.53879/id.54.11.11170
https://doi.org/10.53879/id.54.11.11170
Publikováno v:
Research on Chemical Intermediates. 44:901-924
N-Benzyltetrahydropyridinyl-4,6-dimethoxy phenyl-substituted 2′-hydroxychalcones SJC1–15 were synthesized using Claisen–Schmidt condensation, their structures confirmed by spectral analysis, and their anticancer activity evaluated. To support t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b13c2e228a595e56880633c5ac04d533
https://doi.org/10.1007/s11164-017-3143-9
https://doi.org/10.1007/s11164-017-3143-9