Zobrazeno 1 - 10
of 18
pro vyhledávání: '"B S, Bender"'
Publikováno v:
The Journal of Immunology. 159:3453-3459
Following influenza infection, aged mice have prolonged viral shedding that is presumably due to lower anti-influenza class I-restricted CD8+ CTL activity. To examine alternative viral clearance mechanisms in immunosenescense, we infected young (1.5-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf2e2091f21fd4b435ec4d982b55a7aa
https://doi.org/10.4049/jimmunol.159.7.3453
https://doi.org/10.4049/jimmunol.159.7.3453
Publikováno v:
New England Journal of Medicine. 334:402-404
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6820128f0e9ab431321e9cb060a3e9df
https://doi.org/10.1056/nejm199602083340614
https://doi.org/10.1056/nejm199602083340614
Publikováno v:
The Journal of Experimental Medicine
To investigate the role of CD8+ T lymphocytes in recovery from influenza pneumonia, we used transgenic mice either homozygous (-/-) or heterozygous (+/-) for beta 2-microglobulin (beta 2-M) gene disruption. These mice lack major histocompatibility co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93009a77d473557c721509a86b4f3dfa
https://doi.org/10.1084/jem.175.4.1143
https://doi.org/10.1084/jem.175.4.1143
Publikováno v:
Immunology. 100(4)
Compared with young mice, old mice infected with influenza virus have significantly higher pulmonary viral titres, although these can be reduced significantly with dietary vitamin E supplementation. T helper 1 (Th1) cytokines, especially interferon-g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::474d7f2f50d6d56c6c2054554e9cbb91
https://pubmed.ncbi.nlm.nih.gov/10929076
https://pubmed.ncbi.nlm.nih.gov/10929076
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 159(7)
Following influenza infection, aged mice have prolonged viral shedding that is presumably due to lower anti-influenza class I-restricted CD8+ CTL activity. To examine alternative viral clearance mechanisms in immunosenescense, we infected young (1.5-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::005bfae59e743bde68eac66d47ec2f8b
https://pubmed.ncbi.nlm.nih.gov/9317144
https://pubmed.ncbi.nlm.nih.gov/9317144
Publikováno v:
The Journal of laboratory and clinical medicine. 126(2)
After influenza challenge, aged mice have prolonged viral shedding that correlates with lower splenic cytotoxic T lymphocyte (CTL) activity. To evaluate the age-related pulmonary cell-mediated immune response to influenza, pulmonary lymphocytes were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::26334ebbb0248040ee62b77b97181a89
https://pubmed.ncbi.nlm.nih.gov/7636390
https://pubmed.ncbi.nlm.nih.gov/7636390
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 264(3)
The effects of increased intracellular concentration of cyclic AMP (cAMP) on cellular immune function of young and aged mice were examined by using an in vitro anti-influenza cytotoxic T-lymphocyte (CTL) assay. We found that increasing intracellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9e1936dce8ec23cdd8d1e7c1a152bd2e
https://pubmed.ncbi.nlm.nih.gov/8383747
https://pubmed.ncbi.nlm.nih.gov/8383747
Autor:
B S, Bender
Publikováno v:
The Journal of family practice. 34(4)
The outpatient management of patients infected with human immunodeficiency syndrome is reviewed. Patients with CD4+ cell counts of greater than 0.5 x 10(9)/L (500/mm3) require no specific intervention except vaccination against influenza, pneumococcu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6438ab35ca8dbe62d346878cfe0b725c
https://pubmed.ncbi.nlm.nih.gov/1348266
https://pubmed.ncbi.nlm.nih.gov/1348266
Autor:
B S, Bender, P A, Small
Publikováno v:
Seminars in respiratory infections. 7(1)
Our understanding of the host defense and pathogenesis of influenza has come from parallel studies in animal models and humans. Infection is initiated by deposition of influenza particles on either the upper respiratory tract epithelium or directly i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ea37b90dcb5240a5acfc6b64a204a267
https://pubmed.ncbi.nlm.nih.gov/1609166
https://pubmed.ncbi.nlm.nih.gov/1609166
Publikováno v:
Immunology. 72(4)
Influenza and pneumonia are leading causes of death in the elderly. Cytotoxic T-lymphocyte activity is responsible for viral clearance after infection and declines with age. We hypothesized that following intranasal infection with influenza virus, ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::07e5902f51c8a280a25ec07cb41e2025
https://pubmed.ncbi.nlm.nih.gov/2037313
https://pubmed.ncbi.nlm.nih.gov/2037313