Zobrazeno 1 - 10
of 10
pro vyhledávání: '"B R Ramazanov"'
Imatinib enchances the sensitivity of gastrointestinal stromal tumors to topoisomerase II inhibitors
Publikováno v:
Успехи молекулярной онкологии, Vol 2, Iss 1, Pp 076-081 (2015)
Objective: to study the sensitivity of gastrointestinal stromal tumors (GISTs) to the topoisomerases type II inhibitors and ability of imatinib to enhance GISTs sensitivity to the chemotherapeutic drugs indicated above.Subjects and Methods. We studie
Externí odkaz:
https://doaj.org/article/38a4a30fa0504f2c97c29df7657fb45c
Autor:
S. V. Boichuk, B. R. Ramazanov, Faina Shakirova, D. E. Tsyplakov, F. V. Deviatov, R. Kh. Zakirov, E. A. Zhitlova, I. F. Akhtiamov
Publikováno v:
Гений oртопедии, Vol 25, Iss 4, Pp 561-568 (2019)
The search for new more effective techniques to repair bone fractures and defects is an urgent task of healthcare. Objective To explore the efficacy of a preparation containing etidronates of lanthanide and calcium ions in regenerative repair of bone
Publikováno v:
Kazan medical journal. 97:245-249
Aim. To study the mechanisms of doxorubicin genotoxic effects in terms of poly-(ADP)-ribose-polymerase (PARP) and the ATM-kinase (Ataxia Telangiectasia Mutated) inhibition in cell lines with different p53 status.Methods. The study was conducted on BJ
Autor:
Sergei Boichuk, A R Galembikova, B R Ramazanov, T. F. Odegova, M. A. Kiselev, N. M. Igidov, S. S. Zykova
Publikováno v:
Pharmaceutical Chemistry Journal. 49:817-820
Recyclization of 5-aryl-2,3-dihydro-2-furandione 3-benzoylhydrazones (I) induced by cyanoacetic ester produced ethyl 2-amino-1-benzamido-4-oxo-5-(2-oxo-2-arylethylidene)-4,5-dihydro-1H-pyrrole-3-carboxylates (IIa-g). The biological activity of the sy
Publikováno v:
Kazan medical journal. 95:888-891
Aim. To assess the expression of various types of DNA repair proteins in gastrointestinal stromal tumors (GISTs) to identify the possible defects in DNA repair pathways and therapeutic targets. Methods. The study was performed on the human fibroblast
Autor:
S V Boychuk, B R Ramazanov
Publikováno v:
Kazan medical journal. 95:307-314
Inherited and acquired abnormalities in DNA damage repair system may lead to cancer and other diseases, as well as to act as one of the key factors determining the patient’s responsiveness to chemo- and radiotherapy. Nowadays, the principles of the
Autor:
Pavel Dunaev, M A Satrutdinov, S V Boychuk, V. A. Anokhin, E A Agafonova, B R Ramazanov, Kh S Khaertynov
Publikováno v:
Kazan medical journal. 94:775-778
Aim. To assess the lymphocyte apoptosis intensity in children with neonatal sepsis. Methods. Lymphocyte apoptosis was assessed in 20 children [of them 16 (80%) prematurely born] with late neonatal sepsis. Bacteriology tests allowed to identify the ca
Publikováno v:
Kazan medical journal. 94:75-79
Aim. To investigate the relationship between PML expression and poly(ADP-ribose)-polymerase (PARP) activity in physiological conditions and at genotoxic stress induced by chemotherapy and ionizing radiation. Methods. The study was conducted on BJ fib
Autor:
B R Ramazanov, Sergei Boichuk, Svetlana Khaibullina, S. S. Zykova, Pavel Dunaev, R R Khusnutdinov, Vincent C. Lombardi, A R Galembikova
Publikováno v:
Anti-cancer drugs. 27(7)
Microtubules are known to be one of the most attractive and validated targets in cancer therapy. However, the clinical use of drugs that affect the dynamic state of microtubules has been hindered by chemoresistance and toxicity issues. Accordingly, t
Autor:
S S, Zykova, S V, Boĭchuk, A R, Galembikova, B R, Ramazanov, I G, Mustafin, N M, Igidov, T F, Odegova
Publikováno v:
Tsitologiia. 56(6)
Some compound refering to the 3-hydroxy-1,5-diaryl-4-pivaloyl-2,5-dihydro-2-pyrrolones have been found to cause an increase in the number of mitotic cells and their subsequent death in vitro. This increased in the number of mitotic cells was not asso