Zobrazeno 1 - 10
of 12
pro vyhledávání: '"B R, Wamhoff"'
Publikováno v:
Circulation Research. 95:981-988
A hallmark of smooth muscle cell (SMC) phenotypic switching in atherosclerotic lesions is suppression of SMC differentiation marker gene expression. Yet little is known regarding the molecular mechanisms that control this process. Here we show that t
Publikováno v:
IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 59(10)
Previous research has demonstrated that acoustic radiation force enhances intravascular microbubble adhesion to blood vessels in the presence of flow for molecular-targeted ultrasound imaging and drug delivery. A prototype acoustic radiation force in
Publikováno v:
2008 IEEE Ultrasonics Symposium.
Millions of stents are implanted worldwide each year in patients with atherosclerotic arteries. Safety concerns relating to drug eluting stents have spurred interest in alternative vessel therapies. We hypothesized that a reporter gene could be deliv
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 28(6)
Objective— We previously demonstrated that upregulation of intermediate-conductance Ca 2+ -activated K + channels (K Ca 3.1) is necessary for mitogen-induced phenotypic modulation in isolated porcine coronary smooth muscle cells (SMCs). The objecti
Publikováno v:
Conditional Mutagenesis: An Approach to Disease Models ISBN: 9783540351085
This chapter will review conditional mouse model systems that have been developed to study gene function in skeletal, cardiac, and vascular smooth muscle cells in vivo with an emphasis on the utility of these models for investigating developmental an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17a5ba43b507ce76cd70cd241c09bf20
https://doi.org/10.1007/978-3-540-35109-2_18
https://doi.org/10.1007/978-3-540-35109-2_18
Publikováno v:
Handbook of experimental pharmacology. (178)
This chapter will review conditional mouse model systems that have been developed to study gene function in skeletal, cardiac, and vascular smooth muscle cells in vivo with an emphasis on the utility of these models for investigating developmental an
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 291(5)
A hallmark of smooth muscle cell (SMC) phenotypic modulation in atherosclerosis and restenosis is suppression of SMC differentiation marker genes, proliferation, and migration. Blockade of intermediate-conductance Ca2+-activated K+channels (IKCa1) ha
Autor:
D K, Bowles, B R, Wamhoff
Publikováno v:
Acta physiologica Scandinavica. 178(2)
Substantial evidence exists supporting the role of chronic exercise in reducing the incidence and severity of coronary vascular disease. Physical inactivity is an independent risk factor for coronary heart disease suggesting that the cardioprotective
Publikováno v:
Journal of vascular research. 39(3)
Atorvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, alters bulk myoplasmic Ca2+ regulation and inhibits phenotypic modulation and proliferation of vascular smooth muscle in culture. Nuclear Ca2+ (Ca(n)) signaling is tightly
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 295(2)
Arterial injury models for coronary artery disease have demonstrated an enhanced expression and function of either the endothelin(A) or endothelin(B) (ET(A) or ET(B)) receptor subtype. We hypothesized that organ culture would enhance the physiologica