Zobrazeno 1 - 5
of 5
pro vyhledávání: '"B R, Fruen"'
Autor:
B. R. Lester, B. R. Fruen
Publikováno v:
Neurochemical Research. 16:913-918
The accumulation of [3H]inositol by mechanically dissociated brain cells and cultured skin fibroblasts from fetal mice was examined. Uptake by both tissues was strongly dependent on temperature and the presence of sodium ions. Brain and fibroblast up
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::586d2716a098fcb1cf255256649024f3
https://doi.org/10.1007/bf00965541
https://doi.org/10.1007/bf00965541
Publikováno v:
Bioscience reports. 21(2)
Malignant hyperthermia (MH) is a pharmacogenetic disorder of skeletal muscle characterized by muscle contracture and life-threatening hypermetabolic crisis following exposure to halogenated anesthetics and depolarizing muscle relaxants during surgery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3e8c28baa4a75cc197e617d837af34ce
https://pubmed.ncbi.nlm.nih.gov/11725864
https://pubmed.ncbi.nlm.nih.gov/11725864
Publikováno v:
The Journal of biological chemistry. 276(17)
As an inhibitor of Ca(2+) release through ryanodine receptor (RYR) channels, the skeletal muscle relaxant dantrolene has proven to be both a valuable experimental probe of intracellular Ca(2+) signaling and a lifesaving treatment for the pharmacogene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e8eea7a18803aa81e29f8c27a6495597
https://pubmed.ncbi.nlm.nih.gov/11278295
https://pubmed.ncbi.nlm.nih.gov/11278295
Publikováno v:
The Journal of biological chemistry. 269(1)
To better understand the mechanisms regulating myoplasmic Ca2+ during muscle activity, we have examined the effect of inorganic phosphate (P(i)) on the ryanodine receptor (RyR) Ca2+ release channel of the sarcoplasmic reticulum (SR). We report that P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c054c2f61c84e0b301504f7f1401fbc0
https://pubmed.ncbi.nlm.nih.gov/8276794
https://pubmed.ncbi.nlm.nih.gov/8276794
Autor:
B R Lester, B R Fruen
Publikováno v:
The Biochemical journal. 270(1)
The inositol metabolism of Down's syndrome (DS, trisomy 21) skin fibroblasts was examined. We report that DS cells accumulated [3H]inositol 2-3-fold faster than did other aneuploid or diploid controls. In contrast, trisomy 21 did not affect the uptak
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd25bba2a2bb3c0eabf1098d19f8717c
https://pubmed.ncbi.nlm.nih.gov/2144418
https://pubmed.ncbi.nlm.nih.gov/2144418