Zobrazeno 1 - 10
of 21
pro vyhledávání: '"B R, Avalos"'
Autor:
B R, Avalos
Publikováno v:
Blood. 88:761-777
Publikováno v:
Blood. 84:1790-1801
Macrophage inflammatory protein-1 alpha (MIP-1 alpha) and its human homologue GOS19.1/LD78 are members of the C-C chemokine/intercrine family of secreted proteins. They have proinflammatory properties and also inhibit cell cycle progression of hemato
Autor:
R A, Nash, J H, Antin, C, Karanes, J W, Fay, B R, Avalos, A M, Yeager, D, Przepiorka, S, Davies, F B, Petersen, P, Bartels, D, Buell, W, Fitzsimmons, C, Anasetti, R, Storb, V, Ratanatharathorn
Publikováno v:
Blood. 96(6)
After the transplantation of unmodified marrow from human leukocyte antigen-matched unrelated donors receiving cyclosporine (CSP) and methotrexate (MTX), the incidence of acute graft-versus-host disease (GVHD) is greater than 75%. Tacrolimus is a mac
Autor:
M G, Hunter, B R, Avalos
Publikováno v:
Blood. 95(6)
Patients with severe congenital neutropenia (SCN) are at increased risk for the development of acute myelogenous leukemia (AML). In the subset of patients with SCN that progresses to AML, acquired mutations in the receptor for granulocyte colony-stim
Autor:
M G, Hunter, B R, Avalos
Publikováno v:
Blood. 93(2)
Acquired mutations in the granulocyte colony-stimulating factor receptor (G-CSFR) occur in a subset of patients with severe congenital neutropenia (SCN) who develop acute myelogenous leukemia (AML). These mutations affect one allele and result in hyp
Autor:
M G, Hunter, B R, Avalos
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 160(10)
Activation of both positive and "negative" or anti-proliferative signals has emerged as a common paradigm for regulation of cell growth through cell surface receptors that regulate immune responses. SHP-1 and -2 and the novel 5'-inositol phosphatase
Publikováno v:
Experimental hematology. 25(2)
Activation of the granulocyte colony-stimulating factor receptor (G-CSFR) induces rapid tyrosine phosphorylation of multiple intracellular substrates in proliferating cells and nonproliferating, terminally differentiated neutrophils. The kinases that
Autor:
E A, Copelan, S L, Penza, P J, Elder, P S, Belt, M D, Scholl, D M, Hehmeyer, S A, Ezzone, T P, Bechtel, B R, Avalos
Publikováno v:
Bone marrow transplantation. 18(5)
Between March 1984 and March 1995, 76 patients with advanced acute myelogenous, acute lymphoblastic, or chronic myelogenous leukemia underwent allogeneic marrow transplantation from HLA-identical or one-antigen mismatched sibling or unrelated donors.
Autor:
J L, Klein, B R, Avalos, P, Belt, C A, Taylor, S A, Ezzone, M D, Scholl, J, Fisher, D, Young, E A, Copelan
Publikováno v:
Bone marrow transplantation. 17(4)
Two major problems of unrelated donor transplantation have been an increased incidence of GVHD and graft failure. Even with HLA identity by microlymphocytotoxicity assay and non-reactive MLC, URD marrow transplant recipients have a higher incidence o
Publikováno v:
Blood. 85(11)
The human granulocyte colony-stimulating factor receptor (hG-CSFR) belongs to the cytokine receptor superfamily. As with other members of this family, the cytoplasmic domain of hG-CSFR lacks intrinsic tyrosine kinase activity. To identify critical re