Zobrazeno 1 - 10
of 31
pro vyhledávání: '"B P Barna"'
Publikováno v:
The Journal of Immunology. 159:812-819
IL-4 is a pleiotrophic cytokine that has been shown to affect cells of the central nervous system. We have demonstrated that IL-4 inhibits DNA synthesis and proliferation in human astroglia expressing IL-4 receptors. In this study, we sought to ident
Publikováno v:
Proceedings of the National Academy of Sciences. 87:5720-5723
We have identified human cultured cell lines that are useful for studying angiotensinogen gene expression and its regulation in the central nervous system. A model cell system of human central nervous system origin expressing angiotensinogen has not
Autor:
T, Komata, Y, Kondo, T, Kanzawa, S, Hirohata, S, Koga, H, Sumiyoshi, S M, Srinivasula, B P, Barna, I M, Germano, M, Takakura, M, Inoue, E S, Alnemri, J W, Shay, S, Kyo, S, Kondo
Publikováno v:
Cancer research. 61(15)
Because the apoptotic pathway is often disrupted in tumor cells, its genetic restoration is a very attractive approach for the treatment of tumors. To treat malignant gliomas with this approach, it would be preferred to restrict induction of apoptosi
Publikováno v:
Cancer research. 60(16)
Malignant gliomas are the most common intracranial tumors and are considered incurable. Therefore, exploration of novel therapeutic modalities is essential. Telomerase is a ribonucleoprotein enzyme that is detected in the vast majority of malignant g
Publikováno v:
Investigative ophthalmologyvisual science. 39(13)
To investigate whether interleukin-1beta-converting enzyme (ICE), a mammalian homologue of the Caenorhabditis elegans cell death gene ced-3, is involved in gamma-irradiation-induced apoptosis (programmed cell death) of human retinoblastoma cells.The
Publikováno v:
Anticancer research. 18(1A)
Clinical hypothyroidism has been associated with prolonged survival in several types of malignancies, but the mechanism of this effect is unknown.In vitro studies of thyroid hormone depletion (via culture in medium containing 5% thyroid hormone-deple
Autor:
S, Kondo, Y, Tanaka, Y, Kondo, Y, Ishizaka, M, Hitomi, T, Haqqi, J, Liu, G H, Barnett, E S, Alnemri, B P, Barna
Publikováno v:
Cancer research. 58(5)
Malignant gliomas are highly aggressive neoplasms that are very resistant to current therapeutic approaches, including irradiation, chemotherapy, and immunotherapy. To improve the prognosis, it is absolutely essential to explore novel modalities of t
Autor:
B P, Barna, G B, Hughes
Publikováno v:
Clinics in laboratory medicine. 17(3)
Involvement of autoimmune mechanisms in sudden-onset, rapidly progressive, bilateral inner ear disease is supported by the following evidence: (1) the inner ear contains immune cells and mediators (immunoglobulins); (2) animal models demonstrate inne
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 159(2)
IL-4 is a pleiotrophic cytokine that has been shown to affect cells of the central nervous system. We have demonstrated that IL-4 inhibits DNA synthesis and proliferation in human astroglia expressing IL-4 receptors. In this study, we sought to ident
Autor:
S, Kondo, T, Morimura, G H, Barnett, Y, Kondo, J W, Peterson, R, Kaakaji, J, Takeuchi, S A, Toms, J, Liu, B, Werbel, B P, Barna
Publikováno v:
Oncogene. 13(8)
Although the molecular events regulating the pathogenesis of malignant astrocytomas remains unclear, the inactivation of tumor suppressor genes may be a key factor. The inactivation of p53 by mutation or deletion, however, is not the only obligatory