Zobrazeno 1 - 10
of 15
pro vyhledávání: '"B P, Halloran"'
Autor:
C Ma, R Fedorak, G G Kaplan, L A Dieleman, S Devlin, N Stern, K I Kroeker, C Seow, Y Leung, K L Novak, B P Halloran, V Huang, K Wong, S Ghosh, R Panaccione
BACKGROUND: Ustekinumab is a monoclonal antibody targeting the p40 subunit of interleukins 12 and 23. Gastroenterologists have begun to prescribe ustekinumab off-label for treatment of Crohn’s disease (CD) due to promising clinical trials but robus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::391fc1c79560c2c7b2a9995c0e065367
https://europepmc.org/articles/PMC6507693/
https://europepmc.org/articles/PMC6507693/
Autor:
K Madill-Thomsen, S Withecomb, M Parkes, V Jovanovic, J Venner, R Fedorak, P Halloran, B P Halloran
BACKGROUND: The assessment of patients with ulcerative colitis (UC) remains a challenge despite rapidly evolving medical therapy. Current assessment with endoscopic scoring and histopathology lacks the granularity to correlate strongly with response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bd88cdd6dc50e8ea84d9b0d373522f6
https://europepmc.org/articles/PMC6508473/
https://europepmc.org/articles/PMC6508473/
Autor:
B. P. Halloran
Publikováno v:
Journal of Clinical Endocrinology & Metabolism. 81:2192-2197
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23ef8bb2ff0181cdee2093c723681e1d
https://doi.org/10.1210/jc.81.6.2192
https://doi.org/10.1210/jc.81.6.2192
Publikováno v:
Gravitational and space biology bulletin : publication of the American Society for Gravitational and Space Biology. 16(2)
Skeletal unloading leads to decreased bone formation and decreased bone mass. Bone resorption is uncoupled from bone formation, contributing to the bone loss. During space flight bone is lost principally from the bones most loaded in the 1 g environm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::059fce175804dfef8cd05dc9be659f4b
https://pubmed.ncbi.nlm.nih.gov/12959131
https://pubmed.ncbi.nlm.nih.gov/12959131
Publikováno v:
Aviation, space, and environmental medicine. 72(8)
Alterations in bone metabolism may be a particularly serious consequence of spaceflight and a major obstacle to long-term space exploration. The effects of spaceflight on bone mechanics are unclear. This study examined the effects of spaceflight on b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::213edf2878f11388548ec22c3694e741
https://pubmed.ncbi.nlm.nih.gov/11506233
https://pubmed.ncbi.nlm.nih.gov/11506233
Publikováno v:
Journal of biomedical materials research. 58(3)
Despite the importance of strain in regulating bone metabolism, knowledge of strains induced in bone in vivo during normal activities is limited to short-term studies. Biodegeneration of the bond between gauge and bone is the principle cause of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::200d91772323df1c10c049e47c3b6379
https://pubmed.ncbi.nlm.nih.gov/11319741
https://pubmed.ncbi.nlm.nih.gov/11319741
Publikováno v:
Aviation, space, and environmental medicine. 71(10)
Potential stresses associated with spaceflight include microgravity, acceleration and deceleration forces, a crowded environment and re-adaptation to normal gravity after landing.We hypothesized that spaceflight would result in histological changes i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::37ca463b1f0e8c4986a2bf2acba922df
https://pubmed.ncbi.nlm.nih.gov/11051311
https://pubmed.ncbi.nlm.nih.gov/11051311
Publikováno v:
Gravitational and space biology bulletin : publication of the American Society for Gravitational and Space Biology. 10(2)
Loss of bone during extended space flight has long been a concern that could limit the ability of humans to explore the universe. Surprisingly the available data do not support the concept that weightlessness leads inexorably to a depleted skeleton u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::72aa893f8935eb2acf93394247d97e1f
https://pubmed.ncbi.nlm.nih.gov/11540113
https://pubmed.ncbi.nlm.nih.gov/11540113
Publikováno v:
The Journal of endocrinology. 153(3)
Parathyroid hormone (PTH) release is regulated by extracellular calcium through a Ca2+ receptor (CaR) located on the surface of the parathyroid cell. With advancing age, the serum concentration of PTH increases, and evidence suggests that the calcium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ace2c5b5a485e61eb2176ac40796fa9
https://pubmed.ncbi.nlm.nih.gov/9203998
https://pubmed.ncbi.nlm.nih.gov/9203998
Autor:
B P, Halloran
Publikováno v:
Advances in experimental medicine and biology. 352
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::03a5ce6949775052ea8d97a6a3bef948
https://pubmed.ncbi.nlm.nih.gov/7832052
https://pubmed.ncbi.nlm.nih.gov/7832052