Zobrazeno 1 - 10
of 19
pro vyhledávání: '"B P, Damiano"'
Publikováno v:
Biotechnic & Histochemistry. 85:195-204
We previously reported a sensitive, quantitative immunohistochemical assay using formalin fixed, paraffin embedded rat testicular tissues to assess the degree of proliferation-related toxicity. An indexing scheme was devised based on the percentage o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e582034842f750408fef2e392b8e325
https://doi.org/10.3109/10520290903547778
https://doi.org/10.3109/10520290903547778
Publikováno v:
Biotechnic & Histochemistry. 83:211-220
It is well known that toxicants such as cyclophosphamide and ethanol can have deleterious effects on normal spermatogenesis. End points such as testis weight and sperm counts have been used widely to assess gross structural and functional changes in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20d293843fc6f8d0304943dd1af6915d
https://doi.org/10.1080/10520290802521804
https://doi.org/10.1080/10520290802521804
Publikováno v:
Biochemistry (Moscow). 67:56-64
The serine protease thrombin is well recognized as being pivotal to the maintenance of hemostasis under both normal and pathological conditions. Its cellular actions are mediated through a unique family of protease-activated receptors (PARs). These r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e63c211eacad8afb5cc3b2b375b5623
https://doi.org/10.1023/a:1013900130415
https://doi.org/10.1023/a:1013900130415
Autor:
J-s, Qi, R, Schulingkamp, T J, Parry, R, Colburn, D, Stone, B, Haertlein, L K, Minor, P, Andrade-Gordon, B P, Damiano
Publikováno v:
British journal of pharmacology. 150(4)
While investigating the effects of systemic urotensin II (U-II), a potent vasoactive peptide acting at the UT receptor, we observed ear pinna flushing after systemic administration to conscious rats. In the present study, U-II-induced ear flushing wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8bcca775f29afd602046c2f3678bacbe
https://pubmed.ncbi.nlm.nih.gov/17211454
https://pubmed.ncbi.nlm.nih.gov/17211454
Publikováno v:
Biochemistry. Biokhimiia. 67(1)
The serine protease thrombin is well recognized as being pivotal to the maintenance of hemostasis under both normal and pathological conditions. Its cellular actions are mediated through a unique family of protease-activated receptors (PARs). These r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::89d530f43c01bd56274bcb2aa26e6fdd
https://pubmed.ncbi.nlm.nih.gov/11841340
https://pubmed.ncbi.nlm.nih.gov/11841340
Publikováno v:
Thrombosis and haemostasis. 86(5)
The response to vascular injury is a complex wound healing response involving cell proliferation, migration, remodeling and inflammation. In the present studies we employed a rat balloon angioplasty model of vascular injury to investigate the potenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6b169b6c8bdeea75d19bcce0cbef16f6
https://pubmed.ncbi.nlm.nih.gov/11816724
https://pubmed.ncbi.nlm.nih.gov/11816724
Autor:
P, Andrade-Gordon, C K, Derian, B E, Maryanoff, H C, Zhang, M F, Addo, Cheung Wm, B P, Damiano, M R, D'Andrea, A L, Darrow, L, de Garavilla, A J, Eckardt, E C, Giardino, B J, Haertlein, D F, McComsey
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 298(1)
Human platelets possess two distinct thrombin-activated receptors, PAR-1 (protease-activated receptor-1) and PAR-4, whereas human vascular smooth muscle cells possess only PAR-1. Although such thrombin receptors have been studied extensively in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::18a00983bda7a1b6bd81fc0953668bf9
https://pubmed.ncbi.nlm.nih.gov/11408522
https://pubmed.ncbi.nlm.nih.gov/11408522
Publikováno v:
Thrombosis and haemostasis. 81(5)
Protease-induced cell signaling is mediated by specific receptors such as the emerging family of protease activated receptors (PARs). Since proteases are involved in various aspects of vascular injury, we assessed expression of PAR-2, a protease-acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7e4fc4e2f535b5f21ec6f2170b9e1d36
https://pubmed.ncbi.nlm.nih.gov/10365757
https://pubmed.ncbi.nlm.nih.gov/10365757
Publikováno v:
Canadian journal of physiology and pharmacology. 76(1)
Vascular expression and cellular functions of the thrombin receptor (PAR-1) and protease activated receptor 2 (PAR-2) suggest similar but distinct vascular regulatory roles. The vascular actions of PAR-1 and PAR-2 in vivo were differentiated by monit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3cd9253a4438ede8206439b725b70d9f
https://pubmed.ncbi.nlm.nih.gov/9564545
https://pubmed.ncbi.nlm.nih.gov/9564545
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 279(3)
Thrombin's cellular actions are mediated by a novel G-protein coupled transmembrane receptor. We infused SFLLRN, a peptide that directly activates thrombin receptors, into the left circumflex coronary artery (CFX) of anesthetized dogs to evaluate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::81946781ff63bce7e85df7cbc1746b65
https://pubmed.ncbi.nlm.nih.gov/8968361
https://pubmed.ncbi.nlm.nih.gov/8968361